Tags

Type your tag names separated by a space and hit enter

Effects of a 14-month low-cost maintenance training program in patients with chronic systolic heart failure: a randomized study.
Eur J Cardiovasc Prev Rehabil. 2009 Aug; 16(4):430-7.EJ

Abstract

BACKGROUND

Exercise training is known to be beneficial in chronic heart failure (CHF) patients but there is a lack of studies following patient groups for longer duration with maintenance training programs to defer deconditioning.

METHODS

Study base consisted of all patients diagnosed with CHF in a 3-year period. Sixty-six patients with systolic CHF (ejection fraction <45, New York Heart Association II-III) were randomized to 12 months of either usual care orhome-based maintenance exercise with group training sessions every 2 weeks after an initial 8-week training program. The primary endpoint was maximum workload; secondary endpoints were 6-min walk test, incremental shuttle walk test, sit-to-stand test, quality of life, and serological markers.

RESULTS

Six patients died and 43 completed the study. The initial 8-week training was associated with small but significant improvement in all of the functional tests. In both groups there was a significant decline in the maximum workload the next 12 months (P=0.03 and P<0.001, respectively) but after an adjustment for difference between groups in baseline characteristics, maintenance intervention reduced the decline in the maximum workload by 8.0 W (95% CI: 3.0-13.0, P=0.002). No effect of maintenance intervention was observed for 6-min walk test, incremental shuttle walk test, sit-to-stand test, or quality of life. After 14 months changes in most markers of inflammation, endothelial damage, and glycemic control were more beneficial in the intervention group.

CONCLUSION

A low-cost maintenance intervention in CHF patients reduced the decline in the maximum workload compared with usual care but not in other measures of physical function. Results suggest beneficial effects of long-term maintenance training on glycemic control, inflammation, and endothelial function.

Authors+Show Affiliations

Department of Cardiology, Bispebjerg University Hospital, Copenhagen, Denmark. eva@prescott.dkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19491687

Citation

Prescott, Eva, et al. "Effects of a 14-month Low-cost Maintenance Training Program in Patients With Chronic Systolic Heart Failure: a Randomized Study." European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, vol. 16, no. 4, 2009, pp. 430-7.
Prescott E, Hjardem-Hansen R, Dela F, et al. Effects of a 14-month low-cost maintenance training program in patients with chronic systolic heart failure: a randomized study. Eur J Cardiovasc Prev Rehabil. 2009;16(4):430-7.
Prescott, E., Hjardem-Hansen, R., Dela, F., Ørkild, B., Teisner, A. S., & Nielsen, H. (2009). Effects of a 14-month low-cost maintenance training program in patients with chronic systolic heart failure: a randomized study. European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups On Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 16(4), 430-7. https://doi.org/10.1097/HJR.0b013e32831e94f8
Prescott E, et al. Effects of a 14-month Low-cost Maintenance Training Program in Patients With Chronic Systolic Heart Failure: a Randomized Study. Eur J Cardiovasc Prev Rehabil. 2009;16(4):430-7. PubMed PMID: 19491687.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of a 14-month low-cost maintenance training program in patients with chronic systolic heart failure: a randomized study. AU - Prescott,Eva, AU - Hjardem-Hansen,Rasmus, AU - Dela,Flemming, AU - Ørkild,Bodil, AU - Teisner,Ane S, AU - Nielsen,Henrik, PY - 2009/6/4/entrez PY - 2009/6/6/pubmed PY - 2009/10/30/medline SP - 430 EP - 7 JF - European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology JO - Eur J Cardiovasc Prev Rehabil VL - 16 IS - 4 N2 - BACKGROUND: Exercise training is known to be beneficial in chronic heart failure (CHF) patients but there is a lack of studies following patient groups for longer duration with maintenance training programs to defer deconditioning. METHODS: Study base consisted of all patients diagnosed with CHF in a 3-year period. Sixty-six patients with systolic CHF (ejection fraction <45, New York Heart Association II-III) were randomized to 12 months of either usual care orhome-based maintenance exercise with group training sessions every 2 weeks after an initial 8-week training program. The primary endpoint was maximum workload; secondary endpoints were 6-min walk test, incremental shuttle walk test, sit-to-stand test, quality of life, and serological markers. RESULTS: Six patients died and 43 completed the study. The initial 8-week training was associated with small but significant improvement in all of the functional tests. In both groups there was a significant decline in the maximum workload the next 12 months (P=0.03 and P<0.001, respectively) but after an adjustment for difference between groups in baseline characteristics, maintenance intervention reduced the decline in the maximum workload by 8.0 W (95% CI: 3.0-13.0, P=0.002). No effect of maintenance intervention was observed for 6-min walk test, incremental shuttle walk test, sit-to-stand test, or quality of life. After 14 months changes in most markers of inflammation, endothelial damage, and glycemic control were more beneficial in the intervention group. CONCLUSION: A low-cost maintenance intervention in CHF patients reduced the decline in the maximum workload compared with usual care but not in other measures of physical function. Results suggest beneficial effects of long-term maintenance training on glycemic control, inflammation, and endothelial function. SN - 1741-8275 UR - https://www.unboundmedicine.com/medline/citation/19491687/Effects_of_a_14_month_low_cost_maintenance_training_program_in_patients_with_chronic_systolic_heart_failure:_a_randomized_study_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=19491687.ui DB - PRIME DP - Unbound Medicine ER -