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Optical coherence tomography is helpful in the diagnosis of foveal hypoplasia.
Acta Ophthalmol. 2010 Jun; 88(4):439-42.AO

Abstract

PURPOSE

To investigate whether optical coherence tomography (OCT) is helpful in the diagnosis of foveal hypoplasia in children.

METHODS

Children with albinism and aniridia were examined with Stratus OCT 3 software 4.0.1 (Carl Zeiss Meditec, Dublin, California, USA). A qualitative examination of the macular area was performed with a 128 A-scans/second-single-scan. Macular thickness was measured quantitatively with an automatic fast macular map protocol. The average thickness/volume of the macula was presented as numerical values and as a false colour code in nine modified early treatment of diabetic retinopathy study (ETDRS) areas (A1-A9). A previously collected control group of children was used for comparison.

RESULTS

Macular thickness in 13 children with albinism and three children with aniridia was measured with OCT. Comparison with healthy children in the same population was performed. Patients with albinism and aniridia had significantly thicker central macula (A1) and foveola than children in the control group.

CONCLUSION

OCT was found to be useful in the diagnosis of foveal hypoplasia in children.

Authors+Show Affiliations

Department of Ophthalmology, University Hospital, Uppsala, Sweden. gerd.holmstrom@ogon.uu.seNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19493249

Citation

Holmström, Gerd, et al. "Optical Coherence Tomography Is Helpful in the Diagnosis of Foveal Hypoplasia." Acta Ophthalmologica, vol. 88, no. 4, 2010, pp. 439-42.
Holmström G, Eriksson U, Hellgren K, et al. Optical coherence tomography is helpful in the diagnosis of foveal hypoplasia. Acta Ophthalmol. 2010;88(4):439-42.
Holmström, G., Eriksson, U., Hellgren, K., & Larsson, E. (2010). Optical coherence tomography is helpful in the diagnosis of foveal hypoplasia. Acta Ophthalmologica, 88(4), 439-42. https://doi.org/10.1111/j.1755-3768.2009.01533.x
Holmström G, et al. Optical Coherence Tomography Is Helpful in the Diagnosis of Foveal Hypoplasia. Acta Ophthalmol. 2010;88(4):439-42. PubMed PMID: 19493249.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Optical coherence tomography is helpful in the diagnosis of foveal hypoplasia. AU - Holmström,Gerd, AU - Eriksson,Urban, AU - Hellgren,Kerstin, AU - Larsson,Eva, Y1 - 2009/06/02/ PY - 2009/6/5/entrez PY - 2009/6/6/pubmed PY - 2010/8/6/medline SP - 439 EP - 42 JF - Acta ophthalmologica JO - Acta Ophthalmol VL - 88 IS - 4 N2 - PURPOSE: To investigate whether optical coherence tomography (OCT) is helpful in the diagnosis of foveal hypoplasia in children. METHODS: Children with albinism and aniridia were examined with Stratus OCT 3 software 4.0.1 (Carl Zeiss Meditec, Dublin, California, USA). A qualitative examination of the macular area was performed with a 128 A-scans/second-single-scan. Macular thickness was measured quantitatively with an automatic fast macular map protocol. The average thickness/volume of the macula was presented as numerical values and as a false colour code in nine modified early treatment of diabetic retinopathy study (ETDRS) areas (A1-A9). A previously collected control group of children was used for comparison. RESULTS: Macular thickness in 13 children with albinism and three children with aniridia was measured with OCT. Comparison with healthy children in the same population was performed. Patients with albinism and aniridia had significantly thicker central macula (A1) and foveola than children in the control group. CONCLUSION: OCT was found to be useful in the diagnosis of foveal hypoplasia in children. SN - 1755-3768 UR - https://www.unboundmedicine.com/medline/citation/19493249/Optical_coherence_tomography_is_helpful_in_the_diagnosis_of_foveal_hypoplasia_ L2 - https://doi.org/10.1111/j.1755-3768.2009.01533.x DB - PRIME DP - Unbound Medicine ER -