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Prevalence of symptomatic and asymptomatic peripheral arterial disease and the value of the ankle-brachial index to stratify cardiovascular risk.
Eur J Vasc Endovasc Surg. 2009 Sep; 38(3):305-11.EJ

Abstract

OBJECTIVES

To determine the prevalence of ankle-brachial index (ABI)<0.9 and symptomatic peripheral arterial disease (PAD), association with cardiovascular risk factors (CVRF), and impact of adding ABI measurement to coronary heart disease (CHD) risk screening.

DESIGN

Population-based cross-sectional survey of 6262 participants aged 35-79 in Girona, Spain.

METHODS

Standardized measurements (CVRF, ABI, 10-year CHD risk) and history of intermittent claudication (IC), CHD, and stroke were recorded. ABI<0.9 was considered equivalent to moderate-to-high CHD risk (> or =10%).

RESULTS

ABI<0.9 prevalence was 4.5%. Only 0.62% presented low ABI and IC. Age, current smoker, cardiovascular disease, and uncontrolled hypertension independently associated with ABI<0.9 in both sexes; IC was also associated in men and diabetes in women. Among participants 35-74 free of cardiovascular disease, 6.1% showed moderate-to-high 10-year CHD risk; adding ABI measurement yielded 8.7%. Conversely, the risk function identified 16.8% of these participants as having 10-year CHD risk>10%. In participants 75-79 free of cardiovascular disease, the prevalence of ABI<0.9 (i.e., CHD risk> or =10%) was 11.9%.

CONCLUSIONS

ABI<0.9 is relatively frequent in those 35-79, particularly over 74. However, IC and CHD risk> or =10% indicators are often missing. Adding ABI measurement to CHD-risk screening better identifies moderate-to-high cardiovascular risk patients.

Authors+Show Affiliations

Research on Inflammatory and Cardiovascular Disorders Program (RICAD), Unitat de Lípids i Epidemiologia Cardiovascular (ULEC), Cardiovascular, Epidemiology and Genetics Research Group (EGEC), Institut Municipal d'Investigació Mèdica (IMIM), Barcelona, Spain. rramos.girona.ics@gencat.catNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comment
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19515589

Citation

Ramos, R, et al. "Prevalence of Symptomatic and Asymptomatic Peripheral Arterial Disease and the Value of the Ankle-brachial Index to Stratify Cardiovascular Risk." European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery, vol. 38, no. 3, 2009, pp. 305-11.
Ramos R, Quesada M, Solanas P, et al. Prevalence of symptomatic and asymptomatic peripheral arterial disease and the value of the ankle-brachial index to stratify cardiovascular risk. Eur J Vasc Endovasc Surg. 2009;38(3):305-11.
Ramos, R., Quesada, M., Solanas, P., Subirana, I., Sala, J., Vila, J., Masiá, R., Cerezo, C., Elosua, R., Grau, M., Cordón, F., Juvinyà, D., Fitó, M., Isabel Covas, M., Clarà, A., Angel Muñoz, M., & Marrugat, J. (2009). Prevalence of symptomatic and asymptomatic peripheral arterial disease and the value of the ankle-brachial index to stratify cardiovascular risk. European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery, 38(3), 305-11. https://doi.org/10.1016/j.ejvs.2009.04.013
Ramos R, et al. Prevalence of Symptomatic and Asymptomatic Peripheral Arterial Disease and the Value of the Ankle-brachial Index to Stratify Cardiovascular Risk. Eur J Vasc Endovasc Surg. 2009;38(3):305-11. PubMed PMID: 19515589.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of symptomatic and asymptomatic peripheral arterial disease and the value of the ankle-brachial index to stratify cardiovascular risk. AU - Ramos,R, AU - Quesada,M, AU - Solanas,P, AU - Subirana,I, AU - Sala,J, AU - Vila,J, AU - Masiá,R, AU - Cerezo,C, AU - Elosua,R, AU - Grau,M, AU - Cordón,F, AU - Juvinyà,D, AU - Fitó,M, AU - Isabel Covas,M, AU - Clarà,A, AU - Angel Muñoz,M, AU - Marrugat,J, AU - ,, Y1 - 2009/06/10/ PY - 2009/01/07/received PY - 2009/04/16/accepted PY - 2009/6/12/entrez PY - 2009/6/12/pubmed PY - 2009/8/28/medline SP - 305 EP - 11 JF - European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery JO - Eur J Vasc Endovasc Surg VL - 38 IS - 3 N2 - OBJECTIVES: To determine the prevalence of ankle-brachial index (ABI)<0.9 and symptomatic peripheral arterial disease (PAD), association with cardiovascular risk factors (CVRF), and impact of adding ABI measurement to coronary heart disease (CHD) risk screening. DESIGN: Population-based cross-sectional survey of 6262 participants aged 35-79 in Girona, Spain. METHODS: Standardized measurements (CVRF, ABI, 10-year CHD risk) and history of intermittent claudication (IC), CHD, and stroke were recorded. ABI<0.9 was considered equivalent to moderate-to-high CHD risk (> or =10%). RESULTS: ABI<0.9 prevalence was 4.5%. Only 0.62% presented low ABI and IC. Age, current smoker, cardiovascular disease, and uncontrolled hypertension independently associated with ABI<0.9 in both sexes; IC was also associated in men and diabetes in women. Among participants 35-74 free of cardiovascular disease, 6.1% showed moderate-to-high 10-year CHD risk; adding ABI measurement yielded 8.7%. Conversely, the risk function identified 16.8% of these participants as having 10-year CHD risk>10%. In participants 75-79 free of cardiovascular disease, the prevalence of ABI<0.9 (i.e., CHD risk> or =10%) was 11.9%. CONCLUSIONS: ABI<0.9 is relatively frequent in those 35-79, particularly over 74. However, IC and CHD risk> or =10% indicators are often missing. Adding ABI measurement to CHD-risk screening better identifies moderate-to-high cardiovascular risk patients. SN - 1532-2165 UR - https://www.unboundmedicine.com/medline/citation/19515589/Prevalence_of_symptomatic_and_asymptomatic_peripheral_arterial_disease_and_the_value_of_the_ankle_brachial_index_to_stratify_cardiovascular_risk_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1078-5884(09)00230-5 DB - PRIME DP - Unbound Medicine ER -