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Gender differences in axis I and axis II comorbidity in patients with borderline personality disorder.
Psychopathology. 2009; 42(4):257-63.P

Abstract

BACKGROUND/AIMS

Differences in the clinical presentation of men and women with borderline personality disorder (BPD) are of potential interest for investigations into the neurobiology, genetics, natural history, and treatment response of BPD. The purpose of this study was to investigate gender differences in axis I and axis II comorbidity and in diagnostic criteria in BPD patients.

METHODS

110 women and 49 men with BPD were assessed with the computer-based version of the Munich-Composite International Diagnostic Interview and the Structured Clinical Interview for DSM-IV Personality Disorders. Gender differences were investigated for the following outcomes: (a) lifetime, 12-month and 4-week prevalence of axis I disorders; (b) axis II disorders, and (c) DSM-IV BPD diagnostic criteria.

RESULTS

With regard to lifetime prevalence of axis I disorders, men more often displayed a substance use disorder, in particular alcohol dependency (65 vs. 43%); on the other hand, women more frequently had an affective (94 vs. 82%), anxiety (92 vs. 80%) or eating disorder (35 vs. 18%), in particular anorexia nervosa (21 vs. 4%). Regarding the 12-month prevalence, we found significantly more women suffering from anorexia nervosa (13 vs. 0%). Considering the 4-week prevalence, there were no significant gender differences. With regard to axis II disorders, men had a higher frequency of antisocial personality disorder (57 vs. 26%). Regarding the BPD diagnostic criteria, men more often displayed 'intensive anger' (74 vs. 49%), whereas women more frequently showed 'affective instability' (94 vs. 82%).

CONCLUSION

In this German study, we could replicate and extend the findings from previous US studies, where men and women with BPD showed important differences in their pattern of psychiatric comorbidity. The implications for clinicians and researchers are discussed.

Authors+Show Affiliations

Department of Psychiatry, University of Mainz, Germany. tadic@uni-mainz.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19521142

Citation

Tadić, André, et al. "Gender Differences in Axis I and Axis II Comorbidity in Patients With Borderline Personality Disorder." Psychopathology, vol. 42, no. 4, 2009, pp. 257-63.
Tadić A, Wagner S, Hoch J, et al. Gender differences in axis I and axis II comorbidity in patients with borderline personality disorder. Psychopathology. 2009;42(4):257-63.
Tadić, A., Wagner, S., Hoch, J., Başkaya, O., von Cube, R., Skaletz, C., Lieb, K., & Dahmen, N. (2009). Gender differences in axis I and axis II comorbidity in patients with borderline personality disorder. Psychopathology, 42(4), 257-63. https://doi.org/10.1159/000224149
Tadić A, et al. Gender Differences in Axis I and Axis II Comorbidity in Patients With Borderline Personality Disorder. Psychopathology. 2009;42(4):257-63. PubMed PMID: 19521142.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gender differences in axis I and axis II comorbidity in patients with borderline personality disorder. AU - Tadić,André, AU - Wagner,Stefanie, AU - Hoch,Julia, AU - Başkaya,Omur, AU - von Cube,Robert, AU - Skaletz,Christian, AU - Lieb,Klaus, AU - Dahmen,Norbert, Y1 - 2009/06/12/ PY - 2008/06/30/received PY - 2008/11/25/accepted PY - 2009/6/13/entrez PY - 2009/6/13/pubmed PY - 2009/10/6/medline SP - 257 EP - 63 JF - Psychopathology JO - Psychopathology VL - 42 IS - 4 N2 - BACKGROUND/AIMS: Differences in the clinical presentation of men and women with borderline personality disorder (BPD) are of potential interest for investigations into the neurobiology, genetics, natural history, and treatment response of BPD. The purpose of this study was to investigate gender differences in axis I and axis II comorbidity and in diagnostic criteria in BPD patients. METHODS: 110 women and 49 men with BPD were assessed with the computer-based version of the Munich-Composite International Diagnostic Interview and the Structured Clinical Interview for DSM-IV Personality Disorders. Gender differences were investigated for the following outcomes: (a) lifetime, 12-month and 4-week prevalence of axis I disorders; (b) axis II disorders, and (c) DSM-IV BPD diagnostic criteria. RESULTS: With regard to lifetime prevalence of axis I disorders, men more often displayed a substance use disorder, in particular alcohol dependency (65 vs. 43%); on the other hand, women more frequently had an affective (94 vs. 82%), anxiety (92 vs. 80%) or eating disorder (35 vs. 18%), in particular anorexia nervosa (21 vs. 4%). Regarding the 12-month prevalence, we found significantly more women suffering from anorexia nervosa (13 vs. 0%). Considering the 4-week prevalence, there were no significant gender differences. With regard to axis II disorders, men had a higher frequency of antisocial personality disorder (57 vs. 26%). Regarding the BPD diagnostic criteria, men more often displayed 'intensive anger' (74 vs. 49%), whereas women more frequently showed 'affective instability' (94 vs. 82%). CONCLUSION: In this German study, we could replicate and extend the findings from previous US studies, where men and women with BPD showed important differences in their pattern of psychiatric comorbidity. The implications for clinicians and researchers are discussed. SN - 1423-033X UR - https://www.unboundmedicine.com/medline/citation/19521142/Gender_differences_in_axis_I_and_axis_II_comorbidity_in_patients_with_borderline_personality_disorder_ L2 - https://www.karger.com?DOI=10.1159/000224149 DB - PRIME DP - Unbound Medicine ER -