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Effects of increased occlusal vertical dimension on daily activity and myosin heavy chain composition in rat jaw muscle.
Arch Oral Biol. 2009 Aug; 54(8):783-9.AO

Abstract

Mammalian skeletal muscles change their contractile-protein phenotype in response to mechanical loading and/or chronic electrical stimulation, implying that the phenotypic changes in masticatory muscles might result from new masticatory-loading conditions. To analyze the effects of increased occlusal vertical dimension (OVD) on daily activities and fibre-type compositions in jaw muscles, we measured the total duration of daily activity (duty time) and the myosin heavy chain (MyHC) compositions in the masseter and digastric muscles of freely moving control and bite-opened rats. In the control state, the duty time of the digastric muscle was higher than that of the masseter muscle at activity levels exceeding 5 and 20% of the day's peak activity. The opposite was true at activity levels exceeding 50 and 80% of the day's peak activity. The MyHCs consisted of a mixture of fast and slow types in the digastric muscle. The masseter consisted of mostly fast-type MyHC. The increment of OVD increased not only the duty time at activity levels exceeding 5, 20, 50 and 80% of the day' peak activity in both muscles but also the proportion of MyHC IIa in the masseter muscle and MyHC I in the digastric muscle at the expense of that of MyHC IIb. These results suggest that the increment of OVD changes masseter and digastric muscles towards slower phenotypes by an increase in their daily activities.

Authors+Show Affiliations

Department of Physiology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan. onuki-y@tsurumi-u.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19524215

Citation

Ohnuki, Yoshiki, et al. "Effects of Increased Occlusal Vertical Dimension On Daily Activity and Myosin Heavy Chain Composition in Rat Jaw Muscle." Archives of Oral Biology, vol. 54, no. 8, 2009, pp. 783-9.
Ohnuki Y, Kawai N, Tanaka E, et al. Effects of increased occlusal vertical dimension on daily activity and myosin heavy chain composition in rat jaw muscle. Arch Oral Biol. 2009;54(8):783-9.
Ohnuki, Y., Kawai, N., Tanaka, E., Langenbach, G. E., Tanne, K., & Saeki, Y. (2009). Effects of increased occlusal vertical dimension on daily activity and myosin heavy chain composition in rat jaw muscle. Archives of Oral Biology, 54(8), 783-9. https://doi.org/10.1016/j.archoralbio.2009.05.008
Ohnuki Y, et al. Effects of Increased Occlusal Vertical Dimension On Daily Activity and Myosin Heavy Chain Composition in Rat Jaw Muscle. Arch Oral Biol. 2009;54(8):783-9. PubMed PMID: 19524215.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of increased occlusal vertical dimension on daily activity and myosin heavy chain composition in rat jaw muscle. AU - Ohnuki,Yoshiki, AU - Kawai,Nobuhiko, AU - Tanaka,Eiji, AU - Langenbach,Geerling E J, AU - Tanne,Kazuo, AU - Saeki,Yasutake, Y1 - 2009/06/12/ PY - 2009/02/05/received PY - 2009/05/01/revised PY - 2009/05/04/accepted PY - 2009/6/16/entrez PY - 2009/6/16/pubmed PY - 2010/4/16/medline SP - 783 EP - 9 JF - Archives of oral biology JO - Arch Oral Biol VL - 54 IS - 8 N2 - Mammalian skeletal muscles change their contractile-protein phenotype in response to mechanical loading and/or chronic electrical stimulation, implying that the phenotypic changes in masticatory muscles might result from new masticatory-loading conditions. To analyze the effects of increased occlusal vertical dimension (OVD) on daily activities and fibre-type compositions in jaw muscles, we measured the total duration of daily activity (duty time) and the myosin heavy chain (MyHC) compositions in the masseter and digastric muscles of freely moving control and bite-opened rats. In the control state, the duty time of the digastric muscle was higher than that of the masseter muscle at activity levels exceeding 5 and 20% of the day's peak activity. The opposite was true at activity levels exceeding 50 and 80% of the day's peak activity. The MyHCs consisted of a mixture of fast and slow types in the digastric muscle. The masseter consisted of mostly fast-type MyHC. The increment of OVD increased not only the duty time at activity levels exceeding 5, 20, 50 and 80% of the day' peak activity in both muscles but also the proportion of MyHC IIa in the masseter muscle and MyHC I in the digastric muscle at the expense of that of MyHC IIb. These results suggest that the increment of OVD changes masseter and digastric muscles towards slower phenotypes by an increase in their daily activities. SN - 1879-1506 UR - https://www.unboundmedicine.com/medline/citation/19524215/Effects_of_increased_occlusal_vertical_dimension_on_daily_activity_and_myosin_heavy_chain_composition_in_rat_jaw_muscle_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003-9969(09)00145-9 DB - PRIME DP - Unbound Medicine ER -