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Medical treatment of vestibular disorders.
Expert Opin Pharmacother. 2009 Jul; 10(10):1537-48.EO

Abstract

BACKGROUND

The lifelong prevalence of rotatory vertigo is 30%. Despite this high figure, patients with vertigo generally receive either inappropriate or inadequate treatment. However, the majority of vestibular disorders have a benign cause, take a favorable natural course, and respond positively to therapy.

OBJECTIVE

This review puts special emphasis on the medical rather than the physical, operative, or psychotherapeutic treatments available.

METHODS

A selected review of recent reports and studies on the medical treatment of peripheral and central vestibular disorders.

RESULTS/CONCLUSIONS

In vestibular neuritis, recovery of the peripheral vestibular function can be improved by oral corticosteroids; in Menière's disease, there is first evidence that high-dose, long-term administration of betahistine reduces attack frequency; carbamazepine or oxcarbamazepine is the treatment of first choice in vestibular paroxysmia, a disorder mainly caused by neurovascular cross-compression; the potassium channel blocker aminopyridine provides a new therapeutic principle for treatment of downbeat nystagmus, upbeat nystagmus, and episodic ataxia type 2.

Authors+Show Affiliations

Ludwig-Maximilians-University, Institute of Clinical Neuroscience, Marchioninistr. 15, 81377 Munich, Germany. thomas.brandt@med.uni-muenchen.deNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19527184

Citation

Brandt, Thomas, et al. "Medical Treatment of Vestibular Disorders." Expert Opinion On Pharmacotherapy, vol. 10, no. 10, 2009, pp. 1537-48.
Brandt T, Zwergal A, Strupp M. Medical treatment of vestibular disorders. Expert Opin Pharmacother. 2009;10(10):1537-48.
Brandt, T., Zwergal, A., & Strupp, M. (2009). Medical treatment of vestibular disorders. Expert Opinion On Pharmacotherapy, 10(10), 1537-48. https://doi.org/10.1517/14656560902976879
Brandt T, Zwergal A, Strupp M. Medical Treatment of Vestibular Disorders. Expert Opin Pharmacother. 2009;10(10):1537-48. PubMed PMID: 19527184.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Medical treatment of vestibular disorders. AU - Brandt,Thomas, AU - Zwergal,Andreas, AU - Strupp,Michael, PY - 2009/6/17/entrez PY - 2009/6/17/pubmed PY - 2009/10/9/medline SP - 1537 EP - 48 JF - Expert opinion on pharmacotherapy JO - Expert Opin Pharmacother VL - 10 IS - 10 N2 - BACKGROUND: The lifelong prevalence of rotatory vertigo is 30%. Despite this high figure, patients with vertigo generally receive either inappropriate or inadequate treatment. However, the majority of vestibular disorders have a benign cause, take a favorable natural course, and respond positively to therapy. OBJECTIVE: This review puts special emphasis on the medical rather than the physical, operative, or psychotherapeutic treatments available. METHODS: A selected review of recent reports and studies on the medical treatment of peripheral and central vestibular disorders. RESULTS/CONCLUSIONS: In vestibular neuritis, recovery of the peripheral vestibular function can be improved by oral corticosteroids; in Menière's disease, there is first evidence that high-dose, long-term administration of betahistine reduces attack frequency; carbamazepine or oxcarbamazepine is the treatment of first choice in vestibular paroxysmia, a disorder mainly caused by neurovascular cross-compression; the potassium channel blocker aminopyridine provides a new therapeutic principle for treatment of downbeat nystagmus, upbeat nystagmus, and episodic ataxia type 2. SN - 1744-7666 UR - https://www.unboundmedicine.com/medline/citation/19527184/Medical_treatment_of_vestibular_disorders_ L2 - https://www.tandfonline.com/doi/full/10.1517/14656560902976879 DB - PRIME DP - Unbound Medicine ER -