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A lipohydroxyacid-containing shampoo improves scalp condition and quality of life in patients with seborrheic dermatitis and light-to-moderate scalp psoriasis.
J Cosmet Dermatol. 2009 Jun; 8(2):108-13.JC

Abstract

BACKGROUND

Dandruff is a common scalp disorder affecting almost half of the post-pubertal population of any ethnicity and both genders. It is one of the major reasons for patients to consult a dermatologist and it is the cause of significant psychological and social distress.

AIMS

The aim of this open study was to evaluate the benefit of a 4-week treatment with a shampoo containing 0.1% lipohydroxyacid (LHA) and 1.3% salicylic acid on the scalp condition and on the quality of life of 275 volunteers with seborrheic dermatitis (SD) (n = 226) or light-to-moderate scalp psoriasis (SP) (n = 49).

METHODS

The clinical benefit of the treatment was assessed by scoring the following parameters, i.e., severity of the dermatosis, scaling, itching, excoriations, and superficial burning sensation. The impact on the quality of life was assessed using the Scalpdex, a questionnaire specially developed by Chen et al. for patients with scalp dermatitis, which includes 23 questions regarding the symptoms, functioning and emotions affected by scalp dermatosis.

RESULTS

The shampoo used in this study was well tolerated. After a 4-week treatment, dermatologists noticed a significant clinical improvement of all the scalp parameters evaluated (i.e., the composite lesional score was improved in 91% and 77% of the patients with SD or SP respectively). The symptoms, functioning and emotions scores of quality of life were also significantly improved in relation to the improvement of scalp condition.

CONCLUSION

This study not only allowed a better understanding of the SD and SP patient's profile but also demonstrated that the shampoo evaluated is a convenient, efficient, safe, and well-tolerated cosmetic treatment of SD and light-to-moderate SP improving greatly the quality of life of the treated patients.

Authors+Show Affiliations

La Roche-Posay Laboratoire Pharmaceutique, 110 Avenue Henri Barbusse, 92602 Asnières Cedex, France. sseite@dca.loreal.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article

Language

eng

PubMed ID

19527334

Citation

Seité, S, et al. "A Lipohydroxyacid-containing Shampoo Improves Scalp Condition and Quality of Life in Patients With Seborrheic Dermatitis and Light-to-moderate Scalp Psoriasis." Journal of Cosmetic Dermatology, vol. 8, no. 2, 2009, pp. 108-13.
Seité S, Paries J, Reygagne P, et al. A lipohydroxyacid-containing shampoo improves scalp condition and quality of life in patients with seborrheic dermatitis and light-to-moderate scalp psoriasis. J Cosmet Dermatol. 2009;8(2):108-13.
Seité, S., Paries, J., Reygagne, P., Hamidou, Z., Jouanique, C., Perez-Pala, G., & Rougier, A. (2009). A lipohydroxyacid-containing shampoo improves scalp condition and quality of life in patients with seborrheic dermatitis and light-to-moderate scalp psoriasis. Journal of Cosmetic Dermatology, 8(2), 108-13. https://doi.org/10.1111/j.1473-2165.2009.00431.x
Seité S, et al. A Lipohydroxyacid-containing Shampoo Improves Scalp Condition and Quality of Life in Patients With Seborrheic Dermatitis and Light-to-moderate Scalp Psoriasis. J Cosmet Dermatol. 2009;8(2):108-13. PubMed PMID: 19527334.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A lipohydroxyacid-containing shampoo improves scalp condition and quality of life in patients with seborrheic dermatitis and light-to-moderate scalp psoriasis. AU - Seité,S, AU - Paries,J, AU - Reygagne,P, AU - Hamidou,Z, AU - Jouanique,C, AU - Perez-Pala,G, AU - Rougier,A, PY - 2009/6/17/entrez PY - 2009/6/17/pubmed PY - 2009/11/17/medline SP - 108 EP - 13 JF - Journal of cosmetic dermatology JO - J Cosmet Dermatol VL - 8 IS - 2 N2 - BACKGROUND: Dandruff is a common scalp disorder affecting almost half of the post-pubertal population of any ethnicity and both genders. It is one of the major reasons for patients to consult a dermatologist and it is the cause of significant psychological and social distress. AIMS: The aim of this open study was to evaluate the benefit of a 4-week treatment with a shampoo containing 0.1% lipohydroxyacid (LHA) and 1.3% salicylic acid on the scalp condition and on the quality of life of 275 volunteers with seborrheic dermatitis (SD) (n = 226) or light-to-moderate scalp psoriasis (SP) (n = 49). METHODS: The clinical benefit of the treatment was assessed by scoring the following parameters, i.e., severity of the dermatosis, scaling, itching, excoriations, and superficial burning sensation. The impact on the quality of life was assessed using the Scalpdex, a questionnaire specially developed by Chen et al. for patients with scalp dermatitis, which includes 23 questions regarding the symptoms, functioning and emotions affected by scalp dermatosis. RESULTS: The shampoo used in this study was well tolerated. After a 4-week treatment, dermatologists noticed a significant clinical improvement of all the scalp parameters evaluated (i.e., the composite lesional score was improved in 91% and 77% of the patients with SD or SP respectively). The symptoms, functioning and emotions scores of quality of life were also significantly improved in relation to the improvement of scalp condition. CONCLUSION: This study not only allowed a better understanding of the SD and SP patient's profile but also demonstrated that the shampoo evaluated is a convenient, efficient, safe, and well-tolerated cosmetic treatment of SD and light-to-moderate SP improving greatly the quality of life of the treated patients. SN - 1473-2165 UR - https://www.unboundmedicine.com/medline/citation/19527334/A_lipohydroxyacid_containing_shampoo_improves_scalp_condition_and_quality_of_life_in_patients_with_seborrheic_dermatitis_and_light_to_moderate_scalp_psoriasis_ L2 - https://doi.org/10.1111/j.1473-2165.2009.00431.x DB - PRIME DP - Unbound Medicine ER -