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Impedance plethysmography in the diagnosis of asymptomatic deep vein thrombosis in hip surgery. A venography-controlled study.
Arch Intern Med. 1991 Nov; 151(11):2167-71.AI

Abstract

We prospectively evaluated the accuracy of computerized impedance plethysmography (CIP) in the diagnosis of asymptomatic deep vein thrombosis (DVT) in 246 consecutive high-risk patients scheduled for hip surgery, with bilateral venography used for comparison. The CIP was performed as a surveillance program every third day. If the CIP remained negative, bilateral venography was performed on postoperative day 10 +/- 1 or on day of treatment 14 +/- 1 in nonoperated-on patients. If the CIP became positive, venography was performed within 24 hours. The sensitivity and specificity of CIP for proximal and distal DVT were 19% (confidence interval [CI], 13% to 24%) and 91% (CI, 87% to 94%), respectively. The positive and negative predictive values were 52% (CI, 38% to 65%) and 70% (CI, 65% to 74%), respectively. The sensitivity and specificity of CIP for proximal DVT were 24% (CI, 13% to 34%) and 90% (CI, 87% to 94%), respectively; the positive and negative predictive values were 31% (CI, 20% to 51%) and 87% (CI, 83% to 90%), respectively. We conclude that, because of its low sensitivity, CIP cannot be used in the surveillance of DVT in high-risk patients or for outcome measurements in clinical trials on DVT prophylaxis.

Authors+Show Affiliations

Department of Medical Semiotics, University of Perugia, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

1953218

Citation

Agnelli, G, et al. "Impedance Plethysmography in the Diagnosis of Asymptomatic Deep Vein Thrombosis in Hip Surgery. a Venography-controlled Study." Archives of Internal Medicine, vol. 151, no. 11, 1991, pp. 2167-71.
Agnelli G, Cosmi B, Ranucci V, et al. Impedance plethysmography in the diagnosis of asymptomatic deep vein thrombosis in hip surgery. A venography-controlled study. Arch Intern Med. 1991;151(11):2167-71.
Agnelli, G., Cosmi, B., Ranucci, V., Renga, C., Mosca, S., Lupattelli, L., Di Filippo, P., Rinonapoli, E., & Nenci, G. G. (1991). Impedance plethysmography in the diagnosis of asymptomatic deep vein thrombosis in hip surgery. A venography-controlled study. Archives of Internal Medicine, 151(11), 2167-71.
Agnelli G, et al. Impedance Plethysmography in the Diagnosis of Asymptomatic Deep Vein Thrombosis in Hip Surgery. a Venography-controlled Study. Arch Intern Med. 1991;151(11):2167-71. PubMed PMID: 1953218.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impedance plethysmography in the diagnosis of asymptomatic deep vein thrombosis in hip surgery. A venography-controlled study. AU - Agnelli,G, AU - Cosmi,B, AU - Ranucci,V, AU - Renga,C, AU - Mosca,S, AU - Lupattelli,L, AU - Di Filippo,P, AU - Rinonapoli,E, AU - Nenci,G G, PY - 1991/11/1/pubmed PY - 1991/11/1/medline PY - 1991/11/1/entrez SP - 2167 EP - 71 JF - Archives of internal medicine JO - Arch Intern Med VL - 151 IS - 11 N2 - We prospectively evaluated the accuracy of computerized impedance plethysmography (CIP) in the diagnosis of asymptomatic deep vein thrombosis (DVT) in 246 consecutive high-risk patients scheduled for hip surgery, with bilateral venography used for comparison. The CIP was performed as a surveillance program every third day. If the CIP remained negative, bilateral venography was performed on postoperative day 10 +/- 1 or on day of treatment 14 +/- 1 in nonoperated-on patients. If the CIP became positive, venography was performed within 24 hours. The sensitivity and specificity of CIP for proximal and distal DVT were 19% (confidence interval [CI], 13% to 24%) and 91% (CI, 87% to 94%), respectively. The positive and negative predictive values were 52% (CI, 38% to 65%) and 70% (CI, 65% to 74%), respectively. The sensitivity and specificity of CIP for proximal DVT were 24% (CI, 13% to 34%) and 90% (CI, 87% to 94%), respectively; the positive and negative predictive values were 31% (CI, 20% to 51%) and 87% (CI, 83% to 90%), respectively. We conclude that, because of its low sensitivity, CIP cannot be used in the surveillance of DVT in high-risk patients or for outcome measurements in clinical trials on DVT prophylaxis. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/1953218/Impedance_plethysmography_in_the_diagnosis_of_asymptomatic_deep_vein_thrombosis_in_hip_surgery__A_venography_controlled_study_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/vol/151/pg/2167 DB - PRIME DP - Unbound Medicine ER -