Tags

Type your tag names separated by a space and hit enter

Measurement of common carotid artery intima-media thickness in clinical practice: comparison of B-mode and RF-based technique.
Ultraschall Med 2009; 30(5):459-65UM

Abstract

PURPOSE

The common carotid artery intima-media thickness (CCA-IMT) is usually measured using B-mode ultrasound images. A different approach for CCA-IMT detection is based on radio frequency (RF) multiple M-line analysis.

MATERIALS AND METHODS

The present study explores the relationship between B-mode and RF measurement of CCA-IMT, as well as the reproducibility of both methods in 136 patients recently diagnosed with cardiovascular disease. Within one session, repeated measurements were made in the distal CCA bilaterally, using the B-mode (averaged over 10 mm) and RF technique (averaging 12 M-lines over 14 mm).

RESULTS

The two methods correlate well (Pearson r = 0.765). The CCA-IMT values measured with B-mode and RF were 0.779 +/- 0.196 mm and 0.734 +/- 0.172 mm, respectively. B-mode CCA-IMT is significantly larger than RF CCA-IMT (mean difference of 0.045 mm, SEM 7.8 microm; t = 5.82; p < 0.001). In the multivariate regression analysis, carotid artery stenosis, inhomogeneous IMT and diabetes mellitus were the main predictors of differences between B-mode and RF CCA-IMT. The intrapatient variation for B-mode and RF-based CCA-IMT is comparable (0.05 +/- 0.04 mm and 0.07 +/- 0.05 mm, respectively).

CONCLUSION

CCA-IMT values measured with RF and B-mode have similar reproducibility and exhibit acceptable correlation, but RF CCA-IMT is significantly smaller. The difference between both methods is mainly due to advanced atherosclerosis. Hence, both methods can be used reliably to measure CCA-IMT in clinical practice.

Authors+Show Affiliations

Department of Clinical Neurophysiology, Maastricht University Medical Centre, 6202 AZ Maastricht, Netherlands. fschreuder@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19544231

Citation

Schreuder, F H., et al. "Measurement of Common Carotid Artery Intima-media Thickness in Clinical Practice: Comparison of B-mode and RF-based Technique." Ultraschall in Der Medizin (Stuttgart, Germany : 1980), vol. 30, no. 5, 2009, pp. 459-65.
Schreuder FH, Graf M, Hameleers JM, et al. Measurement of common carotid artery intima-media thickness in clinical practice: comparison of B-mode and RF-based technique. Ultraschall Med. 2009;30(5):459-65.
Schreuder, F. H., Graf, M., Hameleers, J. M., Mess, W. H., & Hoeks, A. P. (2009). Measurement of common carotid artery intima-media thickness in clinical practice: comparison of B-mode and RF-based technique. Ultraschall in Der Medizin (Stuttgart, Germany : 1980), 30(5), pp. 459-65. doi:10.1055/s-0028-1109187.
Schreuder FH, et al. Measurement of Common Carotid Artery Intima-media Thickness in Clinical Practice: Comparison of B-mode and RF-based Technique. Ultraschall Med. 2009;30(5):459-65. PubMed PMID: 19544231.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Measurement of common carotid artery intima-media thickness in clinical practice: comparison of B-mode and RF-based technique. AU - Schreuder,F H, AU - Graf,M, AU - Hameleers,J M, AU - Mess,W H, AU - Hoeks,A P, Y1 - 2009/06/18/ PY - 2009/6/23/entrez PY - 2009/6/23/pubmed PY - 2010/1/14/medline SP - 459 EP - 65 JF - Ultraschall in der Medizin (Stuttgart, Germany : 1980) JO - Ultraschall Med VL - 30 IS - 5 N2 - PURPOSE: The common carotid artery intima-media thickness (CCA-IMT) is usually measured using B-mode ultrasound images. A different approach for CCA-IMT detection is based on radio frequency (RF) multiple M-line analysis. MATERIALS AND METHODS: The present study explores the relationship between B-mode and RF measurement of CCA-IMT, as well as the reproducibility of both methods in 136 patients recently diagnosed with cardiovascular disease. Within one session, repeated measurements were made in the distal CCA bilaterally, using the B-mode (averaged over 10 mm) and RF technique (averaging 12 M-lines over 14 mm). RESULTS: The two methods correlate well (Pearson r = 0.765). The CCA-IMT values measured with B-mode and RF were 0.779 +/- 0.196 mm and 0.734 +/- 0.172 mm, respectively. B-mode CCA-IMT is significantly larger than RF CCA-IMT (mean difference of 0.045 mm, SEM 7.8 microm; t = 5.82; p < 0.001). In the multivariate regression analysis, carotid artery stenosis, inhomogeneous IMT and diabetes mellitus were the main predictors of differences between B-mode and RF CCA-IMT. The intrapatient variation for B-mode and RF-based CCA-IMT is comparable (0.05 +/- 0.04 mm and 0.07 +/- 0.05 mm, respectively). CONCLUSION: CCA-IMT values measured with RF and B-mode have similar reproducibility and exhibit acceptable correlation, but RF CCA-IMT is significantly smaller. The difference between both methods is mainly due to advanced atherosclerosis. Hence, both methods can be used reliably to measure CCA-IMT in clinical practice. SN - 1438-8782 UR - https://www.unboundmedicine.com/medline/citation/19544231/Measurement_of_common_carotid_artery_intima_media_thickness_in_clinical_practice:_comparison_of_B_mode_and_RF_based_technique_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0028-1109187 DB - PRIME DP - Unbound Medicine ER -