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Treatment of depression in diabetes: an update.
Curr Opin Psychiatry 2009; 22(2):211-7CO

Abstract

PURPOSE OF REVIEW

The combination of depression and diabetes is common and especially harmful because depression has a strong impact on psychosocial as well as medical outcomes in patients with diabetes. Consequently, treatment for depression in diabetes is also aimed at improvement in glycemic control and risk reduction for diabetes complications and mortality. This review provides an overview of all published, randomized controlled trials on the treatment of depression in patients with diabetes and summarizes current, ongoing research.

RECENT FINDINGS

The best results for medical and psychological outcomes were observed for psychological treatments; however, the generalizability of these results is restricted by methodological limitations. Most antidepressants were effective treatments for depression in diabetes but failed to show benefits regarding diabetes-related medical variables. Algorithm-based care, including psychological and psychopharmacological approaches, provides the best scientific evidence for successful depression treatment but not for glycemic control.

SUMMARY

Depression can be treated with antidepressants, psychotherapy or a flexible combination of both with relatively good results that are comparable to those for patients who have depression but not diabetes. Up to now, no single treatment that consistently leads to better medical outcomes in patients with both depression and diabetes has been clearly identified.

Authors+Show Affiliations

Department of Psychosomatic Medicine and Psychotherapy, LWL-Clinic Dortmund/Ruhr-University of Bochum, Dortmund, Germany. mail@dr-frank-petrak.deNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19553878

Citation

Petrak, Frank, and Stephan Herpertz. "Treatment of Depression in Diabetes: an Update." Current Opinion in Psychiatry, vol. 22, no. 2, 2009, pp. 211-7.
Petrak F, Herpertz S. Treatment of depression in diabetes: an update. Curr Opin Psychiatry. 2009;22(2):211-7.
Petrak, F., & Herpertz, S. (2009). Treatment of depression in diabetes: an update. Current Opinion in Psychiatry, 22(2), pp. 211-7. doi:10.1097/YCO.0b013e3283207b45.
Petrak F, Herpertz S. Treatment of Depression in Diabetes: an Update. Curr Opin Psychiatry. 2009;22(2):211-7. PubMed PMID: 19553878.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of depression in diabetes: an update. AU - Petrak,Frank, AU - Herpertz,Stephan, PY - 2009/6/26/entrez PY - 2009/6/26/pubmed PY - 2009/9/26/medline SP - 211 EP - 7 JF - Current opinion in psychiatry JO - Curr Opin Psychiatry VL - 22 IS - 2 N2 - PURPOSE OF REVIEW: The combination of depression and diabetes is common and especially harmful because depression has a strong impact on psychosocial as well as medical outcomes in patients with diabetes. Consequently, treatment for depression in diabetes is also aimed at improvement in glycemic control and risk reduction for diabetes complications and mortality. This review provides an overview of all published, randomized controlled trials on the treatment of depression in patients with diabetes and summarizes current, ongoing research. RECENT FINDINGS: The best results for medical and psychological outcomes were observed for psychological treatments; however, the generalizability of these results is restricted by methodological limitations. Most antidepressants were effective treatments for depression in diabetes but failed to show benefits regarding diabetes-related medical variables. Algorithm-based care, including psychological and psychopharmacological approaches, provides the best scientific evidence for successful depression treatment but not for glycemic control. SUMMARY: Depression can be treated with antidepressants, psychotherapy or a flexible combination of both with relatively good results that are comparable to those for patients who have depression but not diabetes. Up to now, no single treatment that consistently leads to better medical outcomes in patients with both depression and diabetes has been clearly identified. SN - 1473-6578 UR - https://www.unboundmedicine.com/medline/citation/19553878/Treatment_of_depression_in_diabetes:_an_update_ L2 - http://Insights.ovid.com/pubmed?pmid=19553878 DB - PRIME DP - Unbound Medicine ER -