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A two-year follow-up study of chronic fatigue syndrome comorbid with psychiatric disorders.
Psychiatry Clin Neurosci. 2009 Jun; 63(3):365-73.PC

Abstract

AIMS

Chronic fatigue syndrome patients often have comorbid psychiatric disorders such as major depressive disorders and anxiety disorders. However, the outcomes of chronic fatigue syndrome and the comorbid psychiatric disorders and the interactions between them are unknown. Therefore, a two-year prospective follow-up study was carried out on chronic fatigue syndrome patients with comorbid psychiatric disorders.

METHODS

A total of 155 patients who met the Japanese case definition of chronic fatigue syndrome were enrolled in this study. Comorbid psychiatric disorders were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders 4th edition criteria. Patients with comorbid psychiatric disorders received psychiatric treatment in addition to medical therapy for chronic fatigue syndrome. Seventy patients participated in a follow-up interview approximately 24 months later.

RESULTS

Of the 70 patients with chronic fatigue syndrome, 33 patients were diagnosed as having comorbid psychiatric disorders including 18 major depressive disorders. Sixteen patients with psychiatric disorders and eight patients with major depressive disorders did not fulfill the criteria of any psychiatric disorders at the follow up. As for chronic fatigue syndrome, nine out of the 70 patients had recovered at the follow up. There is no significant influence of comorbid psychiatric disorders on the outcome of chronic fatigue syndrome.

CONCLUSIONS

Chronic fatigue syndrome patients have a relatively high prevalence of comorbid psychiatric disorders, especially major depressive disorders. The outcomes of chronic fatigue syndrome and psychiatric disorders are independent. Therefore treatment of comorbid psychiatric disorders is necessary in addition to the medical treatment given for chronic fatigue syndrome.

Authors+Show Affiliations

Department of Neuropsychiatry, Osaka City University Graduate School of Medicine, Osaka, Japan. mackham10@yahoo.co.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19566769

Citation

Matsuda, Yasunori, et al. "A Two-year Follow-up Study of Chronic Fatigue Syndrome Comorbid With Psychiatric Disorders." Psychiatry and Clinical Neurosciences, vol. 63, no. 3, 2009, pp. 365-73.
Matsuda Y, Matsui T, Kataoka K, et al. A two-year follow-up study of chronic fatigue syndrome comorbid with psychiatric disorders. Psychiatry Clin Neurosci. 2009;63(3):365-73.
Matsuda, Y., Matsui, T., Kataoka, K., Fukada, R., Fukuda, S., Kuratsune, H., Tajima, S., Yamaguti, K., Kato, Y. H., & Kiriike, N. (2009). A two-year follow-up study of chronic fatigue syndrome comorbid with psychiatric disorders. Psychiatry and Clinical Neurosciences, 63(3), 365-73. https://doi.org/10.1111/j.1440-1819.2009.01954.x
Matsuda Y, et al. A Two-year Follow-up Study of Chronic Fatigue Syndrome Comorbid With Psychiatric Disorders. Psychiatry Clin Neurosci. 2009;63(3):365-73. PubMed PMID: 19566769.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A two-year follow-up study of chronic fatigue syndrome comorbid with psychiatric disorders. AU - Matsuda,Yasunori, AU - Matsui,Tokuzo, AU - Kataoka,Kouhei, AU - Fukada,Ryosuke, AU - Fukuda,Sanae, AU - Kuratsune,Hirohiko, AU - Tajima,Seiki, AU - Yamaguti,Kouzi, AU - Kato,Yukiko Hakariya, AU - Kiriike,Nobuo, PY - 2009/7/2/entrez PY - 2009/7/2/pubmed PY - 2009/9/17/medline SP - 365 EP - 73 JF - Psychiatry and clinical neurosciences JO - Psychiatry Clin Neurosci VL - 63 IS - 3 N2 - AIMS: Chronic fatigue syndrome patients often have comorbid psychiatric disorders such as major depressive disorders and anxiety disorders. However, the outcomes of chronic fatigue syndrome and the comorbid psychiatric disorders and the interactions between them are unknown. Therefore, a two-year prospective follow-up study was carried out on chronic fatigue syndrome patients with comorbid psychiatric disorders. METHODS: A total of 155 patients who met the Japanese case definition of chronic fatigue syndrome were enrolled in this study. Comorbid psychiatric disorders were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders 4th edition criteria. Patients with comorbid psychiatric disorders received psychiatric treatment in addition to medical therapy for chronic fatigue syndrome. Seventy patients participated in a follow-up interview approximately 24 months later. RESULTS: Of the 70 patients with chronic fatigue syndrome, 33 patients were diagnosed as having comorbid psychiatric disorders including 18 major depressive disorders. Sixteen patients with psychiatric disorders and eight patients with major depressive disorders did not fulfill the criteria of any psychiatric disorders at the follow up. As for chronic fatigue syndrome, nine out of the 70 patients had recovered at the follow up. There is no significant influence of comorbid psychiatric disorders on the outcome of chronic fatigue syndrome. CONCLUSIONS: Chronic fatigue syndrome patients have a relatively high prevalence of comorbid psychiatric disorders, especially major depressive disorders. The outcomes of chronic fatigue syndrome and psychiatric disorders are independent. Therefore treatment of comorbid psychiatric disorders is necessary in addition to the medical treatment given for chronic fatigue syndrome. SN - 1440-1819 UR - https://www.unboundmedicine.com/medline/citation/19566769/A_two_year_follow_up_study_of_chronic_fatigue_syndrome_comorbid_with_psychiatric_disorders_ L2 - https://doi.org/10.1111/j.1440-1819.2009.01954.x DB - PRIME DP - Unbound Medicine ER -