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A rare case of large epididymal cyst in androgen insensitivity syndrome removed laparoscopically.
J Minim Invasive Gynecol. 2009 Jul-Aug; 16(4):504-6.JM

Abstract

Androgen insensitivity syndrome is a disorder of sexual differentiation with 46XY karyotype. The gonad is at risk (33% by 50 years of age) for development of malignant tumors. Hence, gonadectomy is warranted. We present a case of a 22-year-old woman diagnosed with androgen insensitivity syndrome during investigation of primary amenorrhea. Ultrasonography showed intraabdominally-located gonads, with a large, nontender cyst of 9.2 x 5.6 x 5.4 cm size, with limited mobility, to the right of the midline. There was also a partial septum, with a wall thickness of 1 to 2 mm and containing clear fluid. Because of suspicion of malignancy, complete surgery including laparoscopic peritoneal cytologic study, gonadectomy, lymphadenectomy, and omentectomy were performed. Histopathologic study showed testis with an epididymal cyst. Formation of epididymal cyst is rare in these cases. The patient did well in the postoperative period. She was put on hormone replacement therapy and is doing well.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. kriplanialka@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19573832

Citation

Kriplani, Alka, et al. "A Rare Case of Large Epididymal Cyst in Androgen Insensitivity Syndrome Removed Laparoscopically." Journal of Minimally Invasive Gynecology, vol. 16, no. 4, 2009, pp. 504-6.
Kriplani A, Savithrisowmya S, Agarwal N, et al. A rare case of large epididymal cyst in androgen insensitivity syndrome removed laparoscopically. J Minim Invasive Gynecol. 2009;16(4):504-6.
Kriplani, A., Savithrisowmya, S., Agarwal, N., Garg, P., Maheswari, D., Ammini, A. C., & Rajan, K. D. (2009). A rare case of large epididymal cyst in androgen insensitivity syndrome removed laparoscopically. Journal of Minimally Invasive Gynecology, 16(4), 504-6. https://doi.org/10.1016/j.jmig.2009.04.013
Kriplani A, et al. A Rare Case of Large Epididymal Cyst in Androgen Insensitivity Syndrome Removed Laparoscopically. J Minim Invasive Gynecol. 2009 Jul-Aug;16(4):504-6. PubMed PMID: 19573832.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A rare case of large epididymal cyst in androgen insensitivity syndrome removed laparoscopically. AU - Kriplani,Alka, AU - Savithrisowmya,S, AU - Agarwal,Nutan, AU - Garg,Pradeep, AU - Maheswari,Deepa, AU - Ammini,A C, AU - Rajan,K D Anand, PY - 2008/11/28/received PY - 2009/04/21/revised PY - 2009/04/26/accepted PY - 2009/7/4/entrez PY - 2009/7/4/pubmed PY - 2009/10/22/medline SP - 504 EP - 6 JF - Journal of minimally invasive gynecology JO - J Minim Invasive Gynecol VL - 16 IS - 4 N2 - Androgen insensitivity syndrome is a disorder of sexual differentiation with 46XY karyotype. The gonad is at risk (33% by 50 years of age) for development of malignant tumors. Hence, gonadectomy is warranted. We present a case of a 22-year-old woman diagnosed with androgen insensitivity syndrome during investigation of primary amenorrhea. Ultrasonography showed intraabdominally-located gonads, with a large, nontender cyst of 9.2 x 5.6 x 5.4 cm size, with limited mobility, to the right of the midline. There was also a partial septum, with a wall thickness of 1 to 2 mm and containing clear fluid. Because of suspicion of malignancy, complete surgery including laparoscopic peritoneal cytologic study, gonadectomy, lymphadenectomy, and omentectomy were performed. Histopathologic study showed testis with an epididymal cyst. Formation of epididymal cyst is rare in these cases. The patient did well in the postoperative period. She was put on hormone replacement therapy and is doing well. SN - 1553-4650 UR - https://www.unboundmedicine.com/medline/citation/19573832/A_rare_case_of_large_epididymal_cyst_in_androgen_insensitivity_syndrome_removed_laparoscopically_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1553-4650(09)00233-7 DB - PRIME DP - Unbound Medicine ER -