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Neuropathology of Lewy body disorders.
Brain Res Bull. 2009 Oct 28; 80(4-5):203-10.BR

Abstract

The spectrum of Lewy body disorders includes not only Parkinson's disease, dementia with Lewy bodies and Parkinson's disease associated dementia but also Lewy body dysphagia and autonomic failure with Lewy bodies. In the last years an increasing number of cases showing Lewy body pathology has been recognised at autopsy. In fact, dementia with Lewy bodies is thought to be the second most frequent degenerative cause of cognitive decline in elderly after Alzheimer's disease, representing about 20% of dementia cases. The clinical diagnosis of dementia with Lewy bodies and of Parkinson's disease dementia is determinant for prognosis and therapeutic management, namely for avoiding increased sensibility to neuroleptics. The recent progress of neuropathology in this field made it possible to define clinical and neuropathological guidelines for the diagnosis. This review briefly describes the most important data of all Lewy body related disorders.

Authors+Show Affiliations

Department of Psychiatry, HUG Belle-Idée, University Hospitals of Geneva, Switzerland. eniko.kovari@hcuge.chNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19576266

Citation

Kövari, Enikö, et al. "Neuropathology of Lewy Body Disorders." Brain Research Bulletin, vol. 80, no. 4-5, 2009, pp. 203-10.
Kövari E, Horvath J, Bouras C. Neuropathology of Lewy body disorders. Brain Res Bull. 2009;80(4-5):203-10.
Kövari, E., Horvath, J., & Bouras, C. (2009). Neuropathology of Lewy body disorders. Brain Research Bulletin, 80(4-5), 203-10. https://doi.org/10.1016/j.brainresbull.2009.06.018
Kövari E, Horvath J, Bouras C. Neuropathology of Lewy Body Disorders. Brain Res Bull. 2009 Oct 28;80(4-5):203-10. PubMed PMID: 19576266.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neuropathology of Lewy body disorders. AU - Kövari,Enikö, AU - Horvath,Judit, AU - Bouras,Constantin, Y1 - 2009/07/01/ PY - 2009/03/31/received PY - 2009/06/18/revised PY - 2009/06/22/accepted PY - 2009/7/7/entrez PY - 2009/7/7/pubmed PY - 2009/11/18/medline SP - 203 EP - 10 JF - Brain research bulletin JO - Brain Res Bull VL - 80 IS - 4-5 N2 - The spectrum of Lewy body disorders includes not only Parkinson's disease, dementia with Lewy bodies and Parkinson's disease associated dementia but also Lewy body dysphagia and autonomic failure with Lewy bodies. In the last years an increasing number of cases showing Lewy body pathology has been recognised at autopsy. In fact, dementia with Lewy bodies is thought to be the second most frequent degenerative cause of cognitive decline in elderly after Alzheimer's disease, representing about 20% of dementia cases. The clinical diagnosis of dementia with Lewy bodies and of Parkinson's disease dementia is determinant for prognosis and therapeutic management, namely for avoiding increased sensibility to neuroleptics. The recent progress of neuropathology in this field made it possible to define clinical and neuropathological guidelines for the diagnosis. This review briefly describes the most important data of all Lewy body related disorders. SN - 1873-2747 UR - https://www.unboundmedicine.com/medline/citation/19576266/Neuropathology_of_Lewy_body_disorders_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0361-9230(09)00200-7 DB - PRIME DP - Unbound Medicine ER -