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Small undifferentiated pancreatic adenocarcinoma which mimics IPMN at imaging.
JOP. 2009 Jul 06; 10(4):406-8.JOP

Abstract

CONTEXT

To present the case of an unusual presentation at imaging of a very small solid undifferentiated pancreatic adenocarcinoma which mimics a side-branch intraductal papillary mucinous neoplasm.

CASE REPORT

The patient came to our hospital for a revaluation of a cystic pancreatic lesion. Ultrasound (US) and contrast-enhanced ultrasound (CEUS) examinations were carried out. A small cystic lesion of about 1.5 cm in diameter was seen in the posterior aspect of the pancreatic uncinate process A very small, solid, vascularized nodule was detected at CEUS within the lesion. Consequently, the patient underwent CT and MRI. MRI confirmed the presence of an intralesional nodule and communication with the main pancreatic duct was demonstrated, suggesting the diagnosis of intraductal papillary mucinous neoplasm with solid intralesional tissue. A pylorus preserving pancreaticoduodenectomy was carried out. An undifferentiated adenocarcinoma having a notable peripheral inflammatory reaction and dilated branch duct was finally diagnosed.

CONCLUSION

To our knowledge, we present for the first time, the case of a very small solid undifferentiated pancreatic adenocarcinoma of the uncinate process which mimicked a side-branch intraductal papillary mucinous neoplasm at imaging. The cystic appearance may be an epiphenomenon of a solid lesion and this possibility has to be considered when one encounters incidental cystic lesions at imaging.

Authors+Show Affiliations

Department of Radiology, G.B. Rossi University Hospital, University of Verona, Italy. mirko.donofrio@univr.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19581744

Citation

D'Onofrio, Mirko, et al. "Small Undifferentiated Pancreatic Adenocarcinoma Which Mimics IPMN at Imaging." JOP : Journal of the Pancreas, vol. 10, no. 4, 2009, pp. 406-8.
D'Onofrio M, Vecchiato F, Gallotti A, et al. Small undifferentiated pancreatic adenocarcinoma which mimics IPMN at imaging. JOP. 2009;10(4):406-8.
D'Onofrio, M., Vecchiato, F., Gallotti, A., Falconi, M., Capelli, P., & Pozzi Mucelli, R. (2009). Small undifferentiated pancreatic adenocarcinoma which mimics IPMN at imaging. JOP : Journal of the Pancreas, 10(4), 406-8.
D'Onofrio M, et al. Small Undifferentiated Pancreatic Adenocarcinoma Which Mimics IPMN at Imaging. JOP. 2009 Jul 6;10(4):406-8. PubMed PMID: 19581744.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Small undifferentiated pancreatic adenocarcinoma which mimics IPMN at imaging. AU - D'Onofrio,Mirko, AU - Vecchiato,Francesca, AU - Gallotti,Anna, AU - Falconi,Massimo, AU - Capelli,Paola, AU - Pozzi Mucelli,Roberto, Y1 - 2009/07/06/ PY - 2009/7/8/entrez PY - 2009/7/8/pubmed PY - 2009/9/29/medline SP - 406 EP - 8 JF - JOP : Journal of the pancreas JO - JOP VL - 10 IS - 4 N2 - CONTEXT: To present the case of an unusual presentation at imaging of a very small solid undifferentiated pancreatic adenocarcinoma which mimics a side-branch intraductal papillary mucinous neoplasm. CASE REPORT: The patient came to our hospital for a revaluation of a cystic pancreatic lesion. Ultrasound (US) and contrast-enhanced ultrasound (CEUS) examinations were carried out. A small cystic lesion of about 1.5 cm in diameter was seen in the posterior aspect of the pancreatic uncinate process A very small, solid, vascularized nodule was detected at CEUS within the lesion. Consequently, the patient underwent CT and MRI. MRI confirmed the presence of an intralesional nodule and communication with the main pancreatic duct was demonstrated, suggesting the diagnosis of intraductal papillary mucinous neoplasm with solid intralesional tissue. A pylorus preserving pancreaticoduodenectomy was carried out. An undifferentiated adenocarcinoma having a notable peripheral inflammatory reaction and dilated branch duct was finally diagnosed. CONCLUSION: To our knowledge, we present for the first time, the case of a very small solid undifferentiated pancreatic adenocarcinoma of the uncinate process which mimicked a side-branch intraductal papillary mucinous neoplasm at imaging. The cystic appearance may be an epiphenomenon of a solid lesion and this possibility has to be considered when one encounters incidental cystic lesions at imaging. SN - 1590-8577 UR - https://www.unboundmedicine.com/medline/citation/19581744/Small_undifferentiated_pancreatic_adenocarcinoma_which_mimics_IPMN_at_imaging_ L2 - https://medlineplus.gov/pancreaticcancer.html DB - PRIME DP - Unbound Medicine ER -