Diastereo- and enantioselective Aza-MBH-type reaction of nitroalkenes to N-tosylimines catalyzed by bifunctional organocatalysts.Org Lett. 2009 Aug 06; 11(15):3310-3.OL
Abstract
The first example of diastereo- and enantioselective aza-MBH-type reaction was accomplished by the asymmetric synthesis of beta-nitro-gamma-enamines via a (1R,2R)-diaminocyclohexane thiourea derivative mediated tandem Michael addition and aza-Henry reaction in good yields (up to 95%) and high enantioselectivities (up to 91% ee) and diastereoselectivities (up to 1:99 dr).
Links
Pub Type(s)
Journal Article
Language
eng
PubMed ID
19583199
Citation
Wang, Xiao, et al. "Diastereo- and Enantioselective Aza-MBH-type Reaction of Nitroalkenes to N-tosylimines Catalyzed By Bifunctional Organocatalysts." Organic Letters, vol. 11, no. 15, 2009, pp. 3310-3.
Wang X, Chen YF, Niu LF, et al. Diastereo- and enantioselective Aza-MBH-type reaction of nitroalkenes to N-tosylimines catalyzed by bifunctional organocatalysts. Org Lett. 2009;11(15):3310-3.
Wang, X., Chen, Y. F., Niu, L. F., & Xu, P. F. (2009). Diastereo- and enantioselective Aza-MBH-type reaction of nitroalkenes to N-tosylimines catalyzed by bifunctional organocatalysts. Organic Letters, 11(15), 3310-3. https://doi.org/10.1021/ol9011458
Wang X, et al. Diastereo- and Enantioselective Aza-MBH-type Reaction of Nitroalkenes to N-tosylimines Catalyzed By Bifunctional Organocatalysts. Org Lett. 2009 Aug 6;11(15):3310-3. PubMed PMID: 19583199.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Diastereo- and enantioselective Aza-MBH-type reaction of nitroalkenes to N-tosylimines catalyzed by bifunctional organocatalysts.
AU - Wang,Xiao,
AU - Chen,Yong-Fei,
AU - Niu,Liang-Feng,
AU - Xu,Peng-Fei,
PY - 2009/7/9/entrez
PY - 2009/7/9/pubmed
PY - 2009/7/9/medline
SP - 3310
EP - 3
JF - Organic letters
JO - Org Lett
VL - 11
IS - 15
N2 - The first example of diastereo- and enantioselective aza-MBH-type reaction was accomplished by the asymmetric synthesis of beta-nitro-gamma-enamines via a (1R,2R)-diaminocyclohexane thiourea derivative mediated tandem Michael addition and aza-Henry reaction in good yields (up to 95%) and high enantioselectivities (up to 91% ee) and diastereoselectivities (up to 1:99 dr).
SN - 1523-7052
UR - https://www.unboundmedicine.com/medline/citation/19583199/Diastereo__and_enantioselective_Aza_MBH_type_reaction_of_nitroalkenes_to_N_tosylimines_catalyzed_by_bifunctional_organocatalysts_
L2 - https://doi.org/10.1021/ol9011458
DB - PRIME
DP - Unbound Medicine
ER -
