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Acute alcohol tolerance on subjective intoxication and simulated driving performance in binge drinkers.
Psychol Addict Behav. 2009 Jun; 23(2):238-47.PA

Abstract

High rates of binge drinking and alcohol-related problems, including drinking and driving, occur among college students. Underlying reasons for the heightened impaired driving rates in this demographic group are not known. The authors hypothesized that acute tolerance to the interoceptive cues of intoxication may contribute to these maladaptive decisions to drive in binge drinkers. Groups of binge-drinking and non-binge-drinking college students (N = 28) attended sessions during which they received a moderate dose of alcohol (0.65 g/kg) or a placebo. The development of acute tolerance to subjective ratings of intoxication and simulated driving performance was assessed by comparing measures taken during the ascending phase and descending phases of the blood alcohol curve. Compared with placebo, alcohol increased ratings of intoxication and impaired multiple aspects of simulated driving performance in both binge and non-binge drinkers. During the descending phase of the blood alcohol curve, binge drinkers showed acute tolerance to alcohol's effect on subjective intoxication, and this effect was accompanied by an increased rating of willingness to drive. By contrast, non-binge drinkers showed no acute tolerance.

Authors+Show Affiliations

Department of Psychology, Northern Kentucky University, Highland Heights, KY 41099, USA. marczinskc1@nku.eduNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19586140

Citation

Marczinski, Cecile A., and Mark T. Fillmore. "Acute Alcohol Tolerance On Subjective Intoxication and Simulated Driving Performance in Binge Drinkers." Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors, vol. 23, no. 2, 2009, pp. 238-47.
Marczinski CA, Fillmore MT. Acute alcohol tolerance on subjective intoxication and simulated driving performance in binge drinkers. Psychol Addict Behav. 2009;23(2):238-47.
Marczinski, C. A., & Fillmore, M. T. (2009). Acute alcohol tolerance on subjective intoxication and simulated driving performance in binge drinkers. Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors, 23(2), 238-47. https://doi.org/10.1037/a0014633
Marczinski CA, Fillmore MT. Acute Alcohol Tolerance On Subjective Intoxication and Simulated Driving Performance in Binge Drinkers. Psychol Addict Behav. 2009;23(2):238-47. PubMed PMID: 19586140.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute alcohol tolerance on subjective intoxication and simulated driving performance in binge drinkers. AU - Marczinski,Cecile A, AU - Fillmore,Mark T, PY - 2009/7/10/entrez PY - 2009/7/10/pubmed PY - 2009/9/19/medline SP - 238 EP - 47 JF - Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors JO - Psychol Addict Behav VL - 23 IS - 2 N2 - High rates of binge drinking and alcohol-related problems, including drinking and driving, occur among college students. Underlying reasons for the heightened impaired driving rates in this demographic group are not known. The authors hypothesized that acute tolerance to the interoceptive cues of intoxication may contribute to these maladaptive decisions to drive in binge drinkers. Groups of binge-drinking and non-binge-drinking college students (N = 28) attended sessions during which they received a moderate dose of alcohol (0.65 g/kg) or a placebo. The development of acute tolerance to subjective ratings of intoxication and simulated driving performance was assessed by comparing measures taken during the ascending phase and descending phases of the blood alcohol curve. Compared with placebo, alcohol increased ratings of intoxication and impaired multiple aspects of simulated driving performance in both binge and non-binge drinkers. During the descending phase of the blood alcohol curve, binge drinkers showed acute tolerance to alcohol's effect on subjective intoxication, and this effect was accompanied by an increased rating of willingness to drive. By contrast, non-binge drinkers showed no acute tolerance. SN - 0893-164X UR - https://www.unboundmedicine.com/medline/citation/19586140/Acute_alcohol_tolerance_on_subjective_intoxication_and_simulated_driving_performance_in_binge_drinkers_ L2 - http://content.apa.org/journals/adb/23/2/238 DB - PRIME DP - Unbound Medicine ER -