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Dietary patterns and breast cancer risk in women participating in the Black Women's Health Study.
Am J Clin Nutr 2009; 90(3):621-8AJ

Abstract

BACKGROUND

No studies have examined dietary patterns and breast cancer risk in a large cohort of African American women.

OBJECTIVE

We investigated the association between dietary patterns and breast cancer risk in the Black Women's Health Study.

DESIGN

This is a prospective cohort study of 50,778 participants followed biennially from 1995 through 2007. During 443,742 person-years of follow-up, 1094 incident cases of breast cancer were identified. Factor analysis was used to derive food patterns based on 69 food variables. We used Cox regression models to obtain incident rate ratios (IRRs) for breast cancer in relation to quintiles of each of the 2 dietary patterns, with adjustment for other breast cancer risk factors.

RESULTS

Through factor analysis, we identified 2 dietary patterns: Western (refined grains, processed meat, and sweets) and prudent (whole grains, vegetables, fruit, and fish). The prudent diet was weakly associated with lower breast cancer risk overall; P for trend = 0.06. In analyses stratified by body mass index (BMI; in kg/m(2)), the prudent dietary pattern was associated with a significantly lower risk of breast cancer in women with a BMI <25 (IRR: 0.64; 95% CI: 0.43, 0.93; P for trend = 0.01). The prudent dietary pattern was also associated with a significantly lower risk of breast cancer in premenopausal women (IRR: 0.70; 95% CI: 0.52, 0.96; P for trend = 0.01), and we found a significant inverse association for the prudent dietary pattern and estrogen receptor-negative breast cancer (IRR: 0.52; 95% CI: 0.28, 0.94; P for trend <0.01).

CONCLUSION

Our findings suggest that the prudent dietary pattern may protect against breast cancer in some black women.

Authors+Show Affiliations

National Cancer Institute, Bethesda, MD 20892-7335, USA. collinsta@mail.nih.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

19587089

Citation

Agurs-Collins, Tanya, et al. "Dietary Patterns and Breast Cancer Risk in Women Participating in the Black Women's Health Study." The American Journal of Clinical Nutrition, vol. 90, no. 3, 2009, pp. 621-8.
Agurs-Collins T, Rosenberg L, Makambi K, et al. Dietary patterns and breast cancer risk in women participating in the Black Women's Health Study. Am J Clin Nutr. 2009;90(3):621-8.
Agurs-Collins, T., Rosenberg, L., Makambi, K., Palmer, J. R., & Adams-Campbell, L. (2009). Dietary patterns and breast cancer risk in women participating in the Black Women's Health Study. The American Journal of Clinical Nutrition, 90(3), pp. 621-8. doi:10.3945/ajcn.2009.27666.
Agurs-Collins T, et al. Dietary Patterns and Breast Cancer Risk in Women Participating in the Black Women's Health Study. Am J Clin Nutr. 2009;90(3):621-8. PubMed PMID: 19587089.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary patterns and breast cancer risk in women participating in the Black Women's Health Study. AU - Agurs-Collins,Tanya, AU - Rosenberg,Lynn, AU - Makambi,Kepher, AU - Palmer,Julie R, AU - Adams-Campbell,Lucile, Y1 - 2009/07/08/ PY - 2009/7/10/entrez PY - 2009/7/10/pubmed PY - 2009/9/30/medline SP - 621 EP - 8 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 90 IS - 3 N2 - BACKGROUND: No studies have examined dietary patterns and breast cancer risk in a large cohort of African American women. OBJECTIVE: We investigated the association between dietary patterns and breast cancer risk in the Black Women's Health Study. DESIGN: This is a prospective cohort study of 50,778 participants followed biennially from 1995 through 2007. During 443,742 person-years of follow-up, 1094 incident cases of breast cancer were identified. Factor analysis was used to derive food patterns based on 69 food variables. We used Cox regression models to obtain incident rate ratios (IRRs) for breast cancer in relation to quintiles of each of the 2 dietary patterns, with adjustment for other breast cancer risk factors. RESULTS: Through factor analysis, we identified 2 dietary patterns: Western (refined grains, processed meat, and sweets) and prudent (whole grains, vegetables, fruit, and fish). The prudent diet was weakly associated with lower breast cancer risk overall; P for trend = 0.06. In analyses stratified by body mass index (BMI; in kg/m(2)), the prudent dietary pattern was associated with a significantly lower risk of breast cancer in women with a BMI <25 (IRR: 0.64; 95% CI: 0.43, 0.93; P for trend = 0.01). The prudent dietary pattern was also associated with a significantly lower risk of breast cancer in premenopausal women (IRR: 0.70; 95% CI: 0.52, 0.96; P for trend = 0.01), and we found a significant inverse association for the prudent dietary pattern and estrogen receptor-negative breast cancer (IRR: 0.52; 95% CI: 0.28, 0.94; P for trend <0.01). CONCLUSION: Our findings suggest that the prudent dietary pattern may protect against breast cancer in some black women. SN - 1938-3207 UR - https://www.unboundmedicine.com/medline/citation/19587089/Dietary_patterns_and_breast_cancer_risk_in_women_participating_in_the_Black_Women's_Health_Study_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.3945/ajcn.2009.27666 DB - PRIME DP - Unbound Medicine ER -