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Evaluation of toxic elements in scalp hair samples of myocardial infarction patients at different stages as related to controls.
Biol Trace Elem Res 2010; 134(1):1-12BT

Abstract

In the present study, the association of arsenic, cadmium, lead, and nickel between scalp hair samples and mortality from myocardial infarction (MI) patients at first, second, and third heart attack was studied. The biological samples of 130 MI patients (77 male and 53 female) age ranged (45-60 years), were collected and 61 healthy persons of same age group (33 male and 28 female) was selected as control subjects. The toxic elements (TEs) in biological samples were assessed by the electrothermal atomic absorption spectrophotometry prior to microwave-assisted acid digestion. The validity of methodology was checked by the certified human hair reference material (BCR 397). It was observed during the study that 78% of 32 patients of the third MI, age >50 years were expired. In these subjects, the level of As, Cd, Ni, and Pb were increased by 10.6%, 19.5%, 15.7%, and 9.8% in the scalp hair as compared to those who tolerated third MI attack (p = 0.12). The high level of toxic metals may play a role in the development of heart disease in the subjects of this study.

Authors+Show Affiliations

National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan. hassanimranafridi@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19588078

Citation

Afridi, Hassan Imran, et al. "Evaluation of Toxic Elements in Scalp Hair Samples of Myocardial Infarction Patients at Different Stages as Related to Controls." Biological Trace Element Research, vol. 134, no. 1, 2010, pp. 1-12.
Afridi HI, Kazi TG, Kazi N, et al. Evaluation of toxic elements in scalp hair samples of myocardial infarction patients at different stages as related to controls. Biol Trace Elem Res. 2010;134(1):1-12.
Afridi, H. I., Kazi, T. G., Kazi, N., Kandhro, G. A., Baig, J. A., Shah, A. Q., ... Arain, M. B. (2010). Evaluation of toxic elements in scalp hair samples of myocardial infarction patients at different stages as related to controls. Biological Trace Element Research, 134(1), pp. 1-12. doi:10.1007/s12011-009-8450-6.
Afridi HI, et al. Evaluation of Toxic Elements in Scalp Hair Samples of Myocardial Infarction Patients at Different Stages as Related to Controls. Biol Trace Elem Res. 2010;134(1):1-12. PubMed PMID: 19588078.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of toxic elements in scalp hair samples of myocardial infarction patients at different stages as related to controls. AU - Afridi,Hassan Imran, AU - Kazi,Tasneem Gul, AU - Kazi,Naveed, AU - Kandhro,Ghulam Abbas, AU - Baig,Jameel Ahmed, AU - Shah,Abdul Qadir, AU - Jamali,Mohammad Khan, AU - Arain,Mohammad Balal, Y1 - 2009/07/09/ PY - 2009/04/09/received PY - 2009/06/25/accepted PY - 2009/7/10/entrez PY - 2009/7/10/pubmed PY - 2010/5/25/medline SP - 1 EP - 12 JF - Biological trace element research JO - Biol Trace Elem Res VL - 134 IS - 1 N2 - In the present study, the association of arsenic, cadmium, lead, and nickel between scalp hair samples and mortality from myocardial infarction (MI) patients at first, second, and third heart attack was studied. The biological samples of 130 MI patients (77 male and 53 female) age ranged (45-60 years), were collected and 61 healthy persons of same age group (33 male and 28 female) was selected as control subjects. The toxic elements (TEs) in biological samples were assessed by the electrothermal atomic absorption spectrophotometry prior to microwave-assisted acid digestion. The validity of methodology was checked by the certified human hair reference material (BCR 397). It was observed during the study that 78% of 32 patients of the third MI, age >50 years were expired. In these subjects, the level of As, Cd, Ni, and Pb were increased by 10.6%, 19.5%, 15.7%, and 9.8% in the scalp hair as compared to those who tolerated third MI attack (p = 0.12). The high level of toxic metals may play a role in the development of heart disease in the subjects of this study. SN - 1559-0720 UR - https://www.unboundmedicine.com/medline/citation/19588078/Evaluation_of_toxic_elements_in_scalp_hair_samples_of_myocardial_infarction_patients_at_different_stages_as_related_to_controls_ L2 - https://dx.doi.org/10.1007/s12011-009-8450-6 DB - PRIME DP - Unbound Medicine ER -