Tags

Type your tag names separated by a space and hit enter

Severe early onset hemolysis, elevated liver enzyme, and low platelet-syndrome in 2 subsequent pregnancies: case report and review of the literature.
Arch Gynecol Obstet. 2010 Feb; 281(2):265-8.AG

Abstract

BACKGROUND

Pregnancies after a previous pregnancy complicated by hemolysis, elevated liver enzyme, and low platelet (HELLP) syndrome carry an increased risk of HELLP-syndrome.

CASE REPORT

We report on a 35-year-old patient with both HELLP-syndrome and fatal neonatal outcome in two subsequent pregnancies with delivery by cesarean section in the 26th and 27th gestational weeks, respectively. The children were immediately admitted to the neonatal intensive care unit but died in their postpartum period. Before the second pregnancy testing for antiphospholipid-syndrome revealed normal results.

CONCLUSION

In general, pregnancies after HELLP-syndrome carry increased risks for pregnancy-related complications. Evaluation of the immunologic status and application of immune-globulins could be diagnostic and therapeutic options in our case. Further research is recommended to evaluate the mechanisms of recurrence of HELLP-syndrome.

Links

Aggregator Full Text

Authors+Show Affiliations

Ott J
Department of Obstetrics and Gynecology, Medical University Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. johannes.ott@meduniwien.ac.at
Poschalko G
No affiliation info available
Zeisler H
No affiliation info available

MeSH

AdultCesarean SectionFatal OutcomeFemaleHELLP SyndromeHumansInfant, NewbornMalePregnancyRecurrence

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19593577

Citation

Ott, Johannes, et al. "Severe Early Onset Hemolysis, Elevated Liver Enzyme, and Low Platelet-syndrome in 2 Subsequent Pregnancies: Case Report and Review of the Literature." Archives of Gynecology and Obstetrics, vol. 281, no. 2, 2010, pp. 265-8.
Ott J, Poschalko G, Zeisler H. Severe early onset hemolysis, elevated liver enzyme, and low platelet-syndrome in 2 subsequent pregnancies: case report and review of the literature. Arch Gynecol Obstet. 2010;281(2):265-8.
Ott, J., Poschalko, G., & Zeisler, H. (2010). Severe early onset hemolysis, elevated liver enzyme, and low platelet-syndrome in 2 subsequent pregnancies: case report and review of the literature. Archives of Gynecology and Obstetrics, 281(2), 265-8. https://doi.org/10.1007/s00404-009-1176-z
Ott J, Poschalko G, Zeisler H. Severe Early Onset Hemolysis, Elevated Liver Enzyme, and Low Platelet-syndrome in 2 Subsequent Pregnancies: Case Report and Review of the Literature. Arch Gynecol Obstet. 2010;281(2):265-8. PubMed PMID: 19593577.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Severe early onset hemolysis, elevated liver enzyme, and low platelet-syndrome in 2 subsequent pregnancies: case report and review of the literature. AU - Ott,Johannes, AU - Poschalko,Gunda, AU - Zeisler,Harald, Y1 - 2009/07/11/ PY - 2009/01/24/received PY - 2009/06/25/accepted PY - 2009/7/14/entrez PY - 2009/7/14/pubmed PY - 2010/4/2/medline SP - 265 EP - 8 JF - Archives of gynecology and obstetrics JO - Arch Gynecol Obstet VL - 281 IS - 2 N2 - BACKGROUND: Pregnancies after a previous pregnancy complicated by hemolysis, elevated liver enzyme, and low platelet (HELLP) syndrome carry an increased risk of HELLP-syndrome. CASE REPORT: We report on a 35-year-old patient with both HELLP-syndrome and fatal neonatal outcome in two subsequent pregnancies with delivery by cesarean section in the 26th and 27th gestational weeks, respectively. The children were immediately admitted to the neonatal intensive care unit but died in their postpartum period. Before the second pregnancy testing for antiphospholipid-syndrome revealed normal results. CONCLUSION: In general, pregnancies after HELLP-syndrome carry increased risks for pregnancy-related complications. Evaluation of the immunologic status and application of immune-globulins could be diagnostic and therapeutic options in our case. Further research is recommended to evaluate the mechanisms of recurrence of HELLP-syndrome. SN - 1432-0711 UR - https://www.unboundmedicine.com/medline/citation/19593577/Severe_early_onset_hemolysis_elevated_liver_enzyme_and_low_platelet_syndrome_in_2_subsequent_pregnancies:_case_report_and_review_of_the_literature_ L2 - https://dx.doi.org/10.1007/s00404-009-1176-z DB - PRIME DP - Unbound Medicine ER -