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The synthesis of biocompatible and SERS-active gold nanoparticles using chitosan.
Nanotechnology. 2009 Aug 05; 20(31):315602.N

Abstract

In this study we present a clean, nontoxic, environmentally friendly synthesis procedure to generate a large variety of gold nanoparticles (GNPs) by using chitosan, a biocompatible, biodegradable, natural polymer, as reducing and stabilizing agent. The formation of gold-chitosan nanocomposites was characterized by UV-vis absorption spectroscopy, transmission electron microscopy (TEM), x-ray diffraction (XRD) and Raman spectroscopy. The results show that the reaction temperature plays a crucial role in controlling the size, shape and crystalline structure of GNPs. In addition, it is demonstrated that chitosan can perform as a scaffold for the assembly of GNPs, which were successfully applied as substrate for surface-enhanced Raman scattering (SERS). To test the SERS activity, a relevant biological molecule--tryptophan--was adopted as the analyte.

Authors+Show Affiliations

Nanobiophotonics Laboratory, Institute for Interdisciplinary Experimental Research and Faculty of Physics, Babes-Bolyai University, M Kogalniceanu 1, 400084 Cluj-Napoca, Romania. potaramonica@yahoo.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19597258

Citation

Potara, Monica, et al. "The Synthesis of Biocompatible and SERS-active Gold Nanoparticles Using Chitosan." Nanotechnology, vol. 20, no. 31, 2009, p. 315602.
Potara M, Maniu D, Astilean S. The synthesis of biocompatible and SERS-active gold nanoparticles using chitosan. Nanotechnology. 2009;20(31):315602.
Potara, M., Maniu, D., & Astilean, S. (2009). The synthesis of biocompatible and SERS-active gold nanoparticles using chitosan. Nanotechnology, 20(31), 315602. https://doi.org/10.1088/0957-4484/20/31/315602
Potara M, Maniu D, Astilean S. The Synthesis of Biocompatible and SERS-active Gold Nanoparticles Using Chitosan. Nanotechnology. 2009 Aug 5;20(31):315602. PubMed PMID: 19597258.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The synthesis of biocompatible and SERS-active gold nanoparticles using chitosan. AU - Potara,Monica, AU - Maniu,Dana, AU - Astilean,Simion, Y1 - 2009/07/14/ PY - 2009/7/15/entrez PY - 2009/7/15/pubmed PY - 2009/9/15/medline SP - 315602 EP - 315602 JF - Nanotechnology JO - Nanotechnology VL - 20 IS - 31 N2 - In this study we present a clean, nontoxic, environmentally friendly synthesis procedure to generate a large variety of gold nanoparticles (GNPs) by using chitosan, a biocompatible, biodegradable, natural polymer, as reducing and stabilizing agent. The formation of gold-chitosan nanocomposites was characterized by UV-vis absorption spectroscopy, transmission electron microscopy (TEM), x-ray diffraction (XRD) and Raman spectroscopy. The results show that the reaction temperature plays a crucial role in controlling the size, shape and crystalline structure of GNPs. In addition, it is demonstrated that chitosan can perform as a scaffold for the assembly of GNPs, which were successfully applied as substrate for surface-enhanced Raman scattering (SERS). To test the SERS activity, a relevant biological molecule--tryptophan--was adopted as the analyte. SN - 1361-6528 UR - https://www.unboundmedicine.com/medline/citation/19597258/The_synthesis_of_biocompatible_and_SERS_active_gold_nanoparticles_using_chitosan_ L2 - https://doi.org/10.1088/0957-4484/20/31/315602 DB - PRIME DP - Unbound Medicine ER -