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The ESCHAR trial: should it change practice?
Perspect Vasc Surg Endovasc Ther. 2009 Jun; 21(2):69-72.PV

Abstract

INTRODUCTION

Most leg ulcers are caused by venous disease, the most common cause of venous hypertension being superficial vein incompetence. The ESCHAR trial tested the value of superficial vein surgery combined with compression in the healing and recurrence of venous leg ulcers compared with compression alone.

METHODS

A total of 500 patients with chronic venous leg ulcers, or recently healed ulcers, were randomized to superficial vein surgery and compression or compression alone. Vein surgery was saphenofemoral ligation and great saphenous stripping and phlebectomy or saphenopopliteal ligation and phlebectomy.

RESULTS

Ulcer healing was virtually identical between the 2 groups at 65% at 24 weeks; subgroup analysis failed to show a benefit for surgery to promote ulcer healing. Ulcer recurrence rate was halved in those that underwent surgery regardless of the presence of deep vein incompetence.

CONCLUSION

Superficial vein surgery should be considered in all leg ulcer sufferers to reduce ulcer recurrence rather than accelerate ulcer healing.

Authors+Show Affiliations

BTG International Limited, London, United Kingdom. david.wright@btgplc.com

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19602507

Citation

Wright, David D I.. "The ESCHAR Trial: Should It Change Practice?" Perspectives in Vascular Surgery and Endovascular Therapy, vol. 21, no. 2, 2009, pp. 69-72.
Wright DD. The ESCHAR trial: should it change practice? Perspect Vasc Surg Endovasc Ther. 2009;21(2):69-72.
Wright, D. D. (2009). The ESCHAR trial: should it change practice? Perspectives in Vascular Surgery and Endovascular Therapy, 21(2), 69-72. https://doi.org/10.1177/1531003509337156
Wright DD. The ESCHAR Trial: Should It Change Practice. Perspect Vasc Surg Endovasc Ther. 2009;21(2):69-72. PubMed PMID: 19602507.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The ESCHAR trial: should it change practice? A1 - Wright,David D I, Y1 - 2009/07/14/ PY - 2009/7/16/entrez PY - 2009/7/16/pubmed PY - 2009/11/6/medline SP - 69 EP - 72 JF - Perspectives in vascular surgery and endovascular therapy JO - Perspect Vasc Surg Endovasc Ther VL - 21 IS - 2 N2 - INTRODUCTION: Most leg ulcers are caused by venous disease, the most common cause of venous hypertension being superficial vein incompetence. The ESCHAR trial tested the value of superficial vein surgery combined with compression in the healing and recurrence of venous leg ulcers compared with compression alone. METHODS: A total of 500 patients with chronic venous leg ulcers, or recently healed ulcers, were randomized to superficial vein surgery and compression or compression alone. Vein surgery was saphenofemoral ligation and great saphenous stripping and phlebectomy or saphenopopliteal ligation and phlebectomy. RESULTS: Ulcer healing was virtually identical between the 2 groups at 65% at 24 weeks; subgroup analysis failed to show a benefit for surgery to promote ulcer healing. Ulcer recurrence rate was halved in those that underwent surgery regardless of the presence of deep vein incompetence. CONCLUSION: Superficial vein surgery should be considered in all leg ulcer sufferers to reduce ulcer recurrence rather than accelerate ulcer healing. SN - 1531-0035 UR - https://www.unboundmedicine.com/medline/citation/19602507/The_ESCHAR_trial:_should_it_change_practice L2 - https://medlineplus.gov/leginjuriesanddisorders.html DB - PRIME DP - Unbound Medicine ER -