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Suicide attempt characteristics may orientate toward a bipolar disorder in attempters with recurrent depression.
J Affect Disord. 2010 Apr; 122(1-2):53-9.JA

Abstract

BACKGROUND

Identification of patients with a bipolar disorder (BPD) among those presenting a major depressive episode is often difficult, resulting in common misdiagnosis and mistreatment. Our aim was to identify clinical variables unrelated to current depressive episode and relevant to suicidal behavior that may help to improve the detection of BPD in suicide attempters presenting with recurrent major depressive disorder.

METHOD

211 patients suffering from recurrent major depressive disorder or BPD, hospitalized after a suicide attempt (SA), were interviewed by semi-structured interview and validated questionnaires about DSM-IV axis I disorders, SA characteristics and a wide range of personality traits relevant to suicidal vulnerability. Multivariate logistic regression analysis was performed to determine differences between RMDD and BPD attempters.

RESULTS

Logistic regression analysis showed that serious SA and family history of suicide are closely associated with a diagnosis of BPD [respectively OR=2.28, p=0.0195; OR=2.98, p=0.0081]. The presence of both characteristics increase the association with BDP [OR=4.78, p=0.005]. Conversely, when looking for the features associated with a serious SA, BPD was the only associated diagnosis [OR=2.03, p=0.004]. Lastly, affect intensity was higher in BPD samples [OR=2.08, p=0.041].

LIMITATIONS

Retrospective nature of the study, lack of the separate analysis of bipolar subtypes.

CONCLUSION

Serious suicide attempt and a familial history of completed suicide in patients with major depression seem to be a clinical marker of bipolarity. Facing suicide attempters with recurrent depression, clinician should be awareness to these characteristics to detect BPD.

Authors+Show Affiliations

Montpellier 1 University, Montpellier F-34006, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19608282

Citation

Guillaume, Sébastien, et al. "Suicide Attempt Characteristics May Orientate Toward a Bipolar Disorder in Attempters With Recurrent Depression." Journal of Affective Disorders, vol. 122, no. 1-2, 2010, pp. 53-9.
Guillaume S, Jaussent I, Jollant F, et al. Suicide attempt characteristics may orientate toward a bipolar disorder in attempters with recurrent depression. J Affect Disord. 2010;122(1-2):53-9.
Guillaume, S., Jaussent, I., Jollant, F., Rihmer, Z., Malafosse, A., & Courtet, P. (2010). Suicide attempt characteristics may orientate toward a bipolar disorder in attempters with recurrent depression. Journal of Affective Disorders, 122(1-2), 53-9. https://doi.org/10.1016/j.jad.2009.06.006
Guillaume S, et al. Suicide Attempt Characteristics May Orientate Toward a Bipolar Disorder in Attempters With Recurrent Depression. J Affect Disord. 2010;122(1-2):53-9. PubMed PMID: 19608282.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Suicide attempt characteristics may orientate toward a bipolar disorder in attempters with recurrent depression. AU - Guillaume,Sébastien, AU - Jaussent,Isabelle, AU - Jollant,Fabrice, AU - Rihmer,Zoltán, AU - Malafosse,Alain, AU - Courtet,Philippe, Y1 - 2009/07/15/ PY - 2009/03/20/received PY - 2009/06/08/revised PY - 2009/06/08/accepted PY - 2009/7/18/entrez PY - 2009/7/18/pubmed PY - 2010/6/3/medline SP - 53 EP - 9 JF - Journal of affective disorders JO - J Affect Disord VL - 122 IS - 1-2 N2 - BACKGROUND: Identification of patients with a bipolar disorder (BPD) among those presenting a major depressive episode is often difficult, resulting in common misdiagnosis and mistreatment. Our aim was to identify clinical variables unrelated to current depressive episode and relevant to suicidal behavior that may help to improve the detection of BPD in suicide attempters presenting with recurrent major depressive disorder. METHOD: 211 patients suffering from recurrent major depressive disorder or BPD, hospitalized after a suicide attempt (SA), were interviewed by semi-structured interview and validated questionnaires about DSM-IV axis I disorders, SA characteristics and a wide range of personality traits relevant to suicidal vulnerability. Multivariate logistic regression analysis was performed to determine differences between RMDD and BPD attempters. RESULTS: Logistic regression analysis showed that serious SA and family history of suicide are closely associated with a diagnosis of BPD [respectively OR=2.28, p=0.0195; OR=2.98, p=0.0081]. The presence of both characteristics increase the association with BDP [OR=4.78, p=0.005]. Conversely, when looking for the features associated with a serious SA, BPD was the only associated diagnosis [OR=2.03, p=0.004]. Lastly, affect intensity was higher in BPD samples [OR=2.08, p=0.041]. LIMITATIONS: Retrospective nature of the study, lack of the separate analysis of bipolar subtypes. CONCLUSION: Serious suicide attempt and a familial history of completed suicide in patients with major depression seem to be a clinical marker of bipolarity. Facing suicide attempters with recurrent depression, clinician should be awareness to these characteristics to detect BPD. SN - 1573-2517 UR - https://www.unboundmedicine.com/medline/citation/19608282/Suicide_attempt_characteristics_may_orientate_toward_a_bipolar_disorder_in_attempters_with_recurrent_depression_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-0327(09)00264-X DB - PRIME DP - Unbound Medicine ER -