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Evaluation of healing and antimicrobiological effects of herbal therapy on venous leg ulcer: pilot study.
Phytother Res 2010; 24(2):277-82PR

Abstract

Venous leg ulcers represent a significant public health problem that will increase as the population ages. Numerous herbs and their extracts are potentially conducive to wound healing, including the ability to serve as an antimicrobial, antifungal, astringent, etc. A total of 32 patients with venous leg ulcers were randomized into two groups: a group with herbal therapy treatment (PT) (17 patients) and a control group (C) (15 patients). The investigation focused on five controls of parameter changes important for ulcer healing and the control of microbiological flora. Within-treatment analysis of the PT group showed that, following herbal therapy treatment, there was a significant decrease in the scores of surface leg ulcer and venous leg ulcer after week 7 of treatment (p < 0.05). In group C following topical antibiotic treatment there was no significant decrease in the surface leg ulcer. Comparing the results of decreased venous leg ulcer surface of the) PT group with the C group showed a significant difference at p < 0.05 after week 7 of treatment. The number of different types of isolated bacterial species decreased significantly (p < 0.05) after the use of herbal preparations. The results of this pilot study demonstrate the healing and antimicrobiological effects of herbal therapy on non-infected venous leg ulcer.

Authors+Show Affiliations

Clinic of Dermatology and Venereology, Clinical Center Nis, Nis, Serbia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

19610037

Citation

Binić, Ivana, et al. "Evaluation of Healing and Antimicrobiological Effects of Herbal Therapy On Venous Leg Ulcer: Pilot Study." Phytotherapy Research : PTR, vol. 24, no. 2, 2010, pp. 277-82.
Binić I, Janković A, Janković D, et al. Evaluation of healing and antimicrobiological effects of herbal therapy on venous leg ulcer: pilot study. Phytother Res. 2010;24(2):277-82.
Binić, I., Janković, A., Janković, D., Janković, I., & Vrucinić, Z. (2010). Evaluation of healing and antimicrobiological effects of herbal therapy on venous leg ulcer: pilot study. Phytotherapy Research : PTR, 24(2), pp. 277-82. doi:10.1002/ptr.2931.
Binić I, et al. Evaluation of Healing and Antimicrobiological Effects of Herbal Therapy On Venous Leg Ulcer: Pilot Study. Phytother Res. 2010;24(2):277-82. PubMed PMID: 19610037.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of healing and antimicrobiological effects of herbal therapy on venous leg ulcer: pilot study. AU - Binić,Ivana, AU - Janković,Aleksandar, AU - Janković,Dimitrije, AU - Janković,Irena, AU - Vrucinić,Zoran, PY - 2009/7/18/entrez PY - 2009/7/18/pubmed PY - 2010/2/27/medline SP - 277 EP - 82 JF - Phytotherapy research : PTR JO - Phytother Res VL - 24 IS - 2 N2 - Venous leg ulcers represent a significant public health problem that will increase as the population ages. Numerous herbs and their extracts are potentially conducive to wound healing, including the ability to serve as an antimicrobial, antifungal, astringent, etc. A total of 32 patients with venous leg ulcers were randomized into two groups: a group with herbal therapy treatment (PT) (17 patients) and a control group (C) (15 patients). The investigation focused on five controls of parameter changes important for ulcer healing and the control of microbiological flora. Within-treatment analysis of the PT group showed that, following herbal therapy treatment, there was a significant decrease in the scores of surface leg ulcer and venous leg ulcer after week 7 of treatment (p < 0.05). In group C following topical antibiotic treatment there was no significant decrease in the surface leg ulcer. Comparing the results of decreased venous leg ulcer surface of the) PT group with the C group showed a significant difference at p < 0.05 after week 7 of treatment. The number of different types of isolated bacterial species decreased significantly (p < 0.05) after the use of herbal preparations. The results of this pilot study demonstrate the healing and antimicrobiological effects of herbal therapy on non-infected venous leg ulcer. SN - 1099-1573 UR - https://www.unboundmedicine.com/medline/citation/19610037/Evaluation_of_healing_and_antimicrobiological_effects_of_herbal_therapy_on_venous_leg_ulcer:_pilot_study_ L2 - https://doi.org/10.1002/ptr.2931 DB - PRIME DP - Unbound Medicine ER -