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Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci.
Fitoterapia 2010; 81(1):30-4F

Abstract

Polygonum cuspidatum root has been traditionally used for the treatment of dental diseases in Korea. The purpose of this study was to evaluate effects of P. cuspidatum root on the development of dental caries, especially its effects against bacterial viability and caries-inducing factors of Streptococcus mutans and Streptococcus sobrinus. Among methanol extract of P. cuspidatum root and its fraction tested, ethyl acetate fraction, composed of polydatin, resveratrol, anthraglycoside B, and emodin, showed inhibitory effects on glycolytic acid production and glucosyltransferase activity of S. mutans and S. sobrinus in addition to antibacterial activities.

Authors+Show Affiliations

Department of Preventive Dentistry, School of Dentistry, Institute of Oral Bioscience and BK 21 program, Chonbuk National University, Jeonju 561-756, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19616082

Citation

Ban, Suk-Ho, et al. "Effects of a Bio-assay Guided Fraction From Polygonum Cuspidatum Root On the Viability, Acid Production and Glucosyltranferase of Mutans Streptococci." Fitoterapia, vol. 81, no. 1, 2010, pp. 30-4.
Ban SH, Kwon YR, Pandit S, et al. Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci. Fitoterapia. 2010;81(1):30-4.
Ban, S. H., Kwon, Y. R., Pandit, S., Lee, Y. S., Yi, H. K., & Jeon, J. G. (2010). Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci. Fitoterapia, 81(1), pp. 30-4. doi:10.1016/j.fitote.2009.06.019.
Ban SH, et al. Effects of a Bio-assay Guided Fraction From Polygonum Cuspidatum Root On the Viability, Acid Production and Glucosyltranferase of Mutans Streptococci. Fitoterapia. 2010;81(1):30-4. PubMed PMID: 19616082.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci. AU - Ban,Suk-Ho, AU - Kwon,Young-Ran, AU - Pandit,Santosh, AU - Lee,Young-Soo, AU - Yi,Ho-Keun, AU - Jeon,Jae-Gyu, Y1 - 2009/07/15/ PY - 2009/06/23/received PY - 2009/06/28/revised PY - 2009/06/30/accepted PY - 2009/7/21/entrez PY - 2009/7/21/pubmed PY - 2010/2/18/medline SP - 30 EP - 4 JF - Fitoterapia JO - Fitoterapia VL - 81 IS - 1 N2 - Polygonum cuspidatum root has been traditionally used for the treatment of dental diseases in Korea. The purpose of this study was to evaluate effects of P. cuspidatum root on the development of dental caries, especially its effects against bacterial viability and caries-inducing factors of Streptococcus mutans and Streptococcus sobrinus. Among methanol extract of P. cuspidatum root and its fraction tested, ethyl acetate fraction, composed of polydatin, resveratrol, anthraglycoside B, and emodin, showed inhibitory effects on glycolytic acid production and glucosyltransferase activity of S. mutans and S. sobrinus in addition to antibacterial activities. SN - 1873-6971 UR - https://www.unboundmedicine.com/medline/citation/19616082/Effects_of_a_bio_assay_guided_fraction_from_Polygonum_cuspidatum_root_on_the_viability_acid_production_and_glucosyltranferase_of_mutans_streptococci_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0367-326X(09)00162-2 DB - PRIME DP - Unbound Medicine ER -