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Hypomagnesemia in type 2 diabetic Omani patients.

Abstract

OBJECTIVE

To study serum total magnesium (Mg) levels in type 2 diabetic Omani patients, and to find the relation between Mg levels and glycosylated hemoglobin (HbA1c), body mass index (BMI), and age of the patient.

METHODS

This work was carried out at the Bousher Polyclinic, Muscat, Oman from January to October 2008. We compared 34 type 2 diabetic patients with non-diabetic subjects as regards serum total Mg. We assessed diabetic patients in terms of age, gender, HbA1c, BMI, and their medications. Subjects at risk for apparent causes of hypomagnesemia or hypermagnesemia were excluded.

RESULTS

The mean serum total Mg level was 0.92 mmol/L (SD 0.06) in the control subjects, and 0.81 mmol/L (SD 0.08) in the diabetic group, and although almost all our diabetic patients have no hypomagnesemia, their levels of serum total Mg were significantly reduced compared with control subjects. T-test shows that our diabetics have significantly lower total Mg levels with a difference of 0.12 mmol/L (p=0.000) irrespective of age and gender. The Mg levels are positively correlated with age, but no correlation with HbA1c and BMI.

CONCLUSION

Although ionized and intracellular Mg levels are more reliable than total serum Mg in assessing Mg deficiency, low total serum levels of Mg are frequently seen in individuals with type 2 diabetes. Further studies on the role of Mg supplementation in the prevention of type 2 diabetes mellitus and its complications and similar studies in type 1 diabetes mellitus are recommended.

Links

Authors+Show Affiliations

,

Department of Internal Medicie, Bousher Polyclinic, Post Code 118, Muscat, Oman. mag_alosali@yahoo.com

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Source

Saudi medical journal 30:7 2009 Jul pg 897-901

MeSH

Adult
Age Factors
Aged
Body Mass Index
Diabetes Mellitus, Type 2
Female
Glycated Hemoglobin A
Humans
Magnesium
Magnesium Deficiency
Male
Middle Aged
Oman
Regression Analysis
Young Adult

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

19618003

Citation

Al-Osali, Magdi E., et al. "Hypomagnesemia in Type 2 Diabetic Omani Patients." Saudi Medical Journal, vol. 30, no. 7, 2009, pp. 897-901.
Al-Osali ME, Al-Qassabi SS, ElSayed MK. Hypomagnesemia in type 2 diabetic Omani patients. Saudi Med J. 2009;30(7):897-901.
Al-Osali, M. E., Al-Qassabi, S. S., & ElSayed, M. K. (2009). Hypomagnesemia in type 2 diabetic Omani patients. Saudi Medical Journal, 30(7), pp. 897-901.
Al-Osali ME, Al-Qassabi SS, ElSayed MK. Hypomagnesemia in Type 2 Diabetic Omani Patients. Saudi Med J. 2009;30(7):897-901. PubMed PMID: 19618003.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hypomagnesemia in type 2 diabetic Omani patients. AU - Al-Osali,Magdi E, AU - Al-Qassabi,Salim S, AU - ElSayed,Medhat K, PY - 2009/7/21/entrez PY - 2009/7/21/pubmed PY - 2009/10/16/medline SP - 897 EP - 901 JF - Saudi medical journal JO - Saudi Med J VL - 30 IS - 7 N2 - OBJECTIVE: To study serum total magnesium (Mg) levels in type 2 diabetic Omani patients, and to find the relation between Mg levels and glycosylated hemoglobin (HbA1c), body mass index (BMI), and age of the patient. METHODS: This work was carried out at the Bousher Polyclinic, Muscat, Oman from January to October 2008. We compared 34 type 2 diabetic patients with non-diabetic subjects as regards serum total Mg. We assessed diabetic patients in terms of age, gender, HbA1c, BMI, and their medications. Subjects at risk for apparent causes of hypomagnesemia or hypermagnesemia were excluded. RESULTS: The mean serum total Mg level was 0.92 mmol/L (SD 0.06) in the control subjects, and 0.81 mmol/L (SD 0.08) in the diabetic group, and although almost all our diabetic patients have no hypomagnesemia, their levels of serum total Mg were significantly reduced compared with control subjects. T-test shows that our diabetics have significantly lower total Mg levels with a difference of 0.12 mmol/L (p=0.000) irrespective of age and gender. The Mg levels are positively correlated with age, but no correlation with HbA1c and BMI. CONCLUSION: Although ionized and intracellular Mg levels are more reliable than total serum Mg in assessing Mg deficiency, low total serum levels of Mg are frequently seen in individuals with type 2 diabetes. Further studies on the role of Mg supplementation in the prevention of type 2 diabetes mellitus and its complications and similar studies in type 1 diabetes mellitus are recommended. SN - 0379-5284 UR - https://www.unboundmedicine.com/medline/citation/19618003/Hypomagnesemia_in_type_2_diabetic_Omani_patients_ L2 - https://medlineplus.gov/diabetestype2.html DB - PRIME DP - Unbound Medicine ER -