Tags

Type your tag names separated by a space and hit enter

Does postprandial coffee intake enhance gastric emptying?: a crossover study using continuous real time 13C breath test (BreathID system).
Hepatogastroenterology. 2009 May-Jun; 56(91-92):918-20.H

Abstract

BACKGROUND/AIMS

Coffee is one of the most popular beverages worldwide, however, few studies have examined the effects of coffee on the gastrointestinal system. The aim of this study was to determine whether there was a correlation between coffee intake and gastric emptying using a novel non-invasive technique for measuring gastric emptying with a continuous real time 13C breath test (BreathID system: Oridion, Israel).

METHODOLOGY

Six healthy male volunteers participated in this randomized, two-way crossover study. The subjects were randomly assigned to receive a test meal (200 kcal per 200 mL) plus postprandial 190 mL black coffee or the test meal alone after fasting overnight. A 13C-acetic acid breath test was continuously performed using the BreathID system, which monitors gastric emptying, for 4 hours after the administration of the test meal. Using Oridion Research Software (beta version), the time for emptying of 50% of the labeled meals (T 1/2) and the analog to the scintigraphy lag time for 10% emptying of the labeled meal (T lag) were calculated. The parameters between two occasions were compared using the Wilcoxon signed-rank test.

RESULTS

After coffee intake the T 1/2 and T lag constant were significantly decreased.

CONCLUSIONS

The decrease in the T 1/2 and T lag suggests the acceleration of gastric emptying. This study showed that postprandial coffee intake enhances gastric emptying, suggesting the potential use of coffee in clinical settings for patients with functional gastrointestinal disorders.

Authors+Show Affiliations

Gastroenterology Division, Yokohama City University School of Medicine, Yokohama, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

19621729

Citation

Akimoto, Keiko, et al. "Does Postprandial Coffee Intake Enhance Gastric Emptying?: a Crossover Study Using Continuous Real Time 13C Breath Test (BreathID System)." Hepato-gastroenterology, vol. 56, no. 91-92, 2009, pp. 918-20.
Akimoto K, Inamori M, Iida H, et al. Does postprandial coffee intake enhance gastric emptying?: a crossover study using continuous real time 13C breath test (BreathID system). Hepatogastroenterology. 2009;56(91-92):918-20.
Akimoto, K., Inamori, M., Iida, H., Endo, H., Akiyama, T., Ikeda, T., Fujita, K., Takahashi, H., Yoneda, M., Goto, A., Abe, Y., Kobayashi, N., Kirikoshi, H., Kubota, K., Saito, S., & Nakajima, A. (2009). Does postprandial coffee intake enhance gastric emptying?: a crossover study using continuous real time 13C breath test (BreathID system). Hepato-gastroenterology, 56(91-92), 918-20.
Akimoto K, et al. Does Postprandial Coffee Intake Enhance Gastric Emptying?: a Crossover Study Using Continuous Real Time 13C Breath Test (BreathID System). Hepatogastroenterology. 2009 May-Jun;56(91-92):918-20. PubMed PMID: 19621729.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does postprandial coffee intake enhance gastric emptying?: a crossover study using continuous real time 13C breath test (BreathID system). AU - Akimoto,Keiko, AU - Inamori,Masahiko, AU - Iida,Hiroshi, AU - Endo,Hiroki, AU - Akiyama,Tomoyuki, AU - Ikeda,Tamon, AU - Fujita,Koji, AU - Takahashi,Hirokazu, AU - Yoneda,Masato, AU - Goto,Ayumu, AU - Abe,Yasunobu, AU - Kobayashi,Noritoshi, AU - Kirikoshi,Hiroyuki, AU - Kubota,Kensuke, AU - Saito,Satoru, AU - Nakajima,Atsushi, PY - 2009/7/23/entrez PY - 2009/7/23/pubmed PY - 2009/9/18/medline SP - 918 EP - 20 JF - Hepato-gastroenterology JO - Hepatogastroenterology VL - 56 IS - 91-92 N2 - BACKGROUND/AIMS: Coffee is one of the most popular beverages worldwide, however, few studies have examined the effects of coffee on the gastrointestinal system. The aim of this study was to determine whether there was a correlation between coffee intake and gastric emptying using a novel non-invasive technique for measuring gastric emptying with a continuous real time 13C breath test (BreathID system: Oridion, Israel). METHODOLOGY: Six healthy male volunteers participated in this randomized, two-way crossover study. The subjects were randomly assigned to receive a test meal (200 kcal per 200 mL) plus postprandial 190 mL black coffee or the test meal alone after fasting overnight. A 13C-acetic acid breath test was continuously performed using the BreathID system, which monitors gastric emptying, for 4 hours after the administration of the test meal. Using Oridion Research Software (beta version), the time for emptying of 50% of the labeled meals (T 1/2) and the analog to the scintigraphy lag time for 10% emptying of the labeled meal (T lag) were calculated. The parameters between two occasions were compared using the Wilcoxon signed-rank test. RESULTS: After coffee intake the T 1/2 and T lag constant were significantly decreased. CONCLUSIONS: The decrease in the T 1/2 and T lag suggests the acceleration of gastric emptying. This study showed that postprandial coffee intake enhances gastric emptying, suggesting the potential use of coffee in clinical settings for patients with functional gastrointestinal disorders. SN - 0172-6390 UR - https://www.unboundmedicine.com/medline/citation/19621729/Does_postprandial_coffee_intake_enhance_gastric_emptying:_a_crossover_study_using_continuous_real_time_13C_breath_test__BreathID_system__ DB - PRIME DP - Unbound Medicine ER -