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Detection and characterization of Enterobacteriaceae producing metallo-beta-lactamases in a tertiary-care hospital in Spain.
Clin Microbiol Infect. 2010 Feb; 16(2):181-3.CM

Abstract

Carbapenem-resistant or intermediate (MIC >or=1 mg/L) clinical isolates (n = 12) of three species of Enterobacteriaceae (Klebsiella pneumoniae, Klebsiella oxytoca and Escherichia coli) were characterized. The isolates harboured integrons containing the VIM-1 metallo-beta-lactamase gene together with other resistance gene cassettes. In particular, the CTX-M-2 gene was detected in four of the K. pneumoniae isolates. The patient population was mostly paediatric and characterized by severe underlying illnesses that involved long-term hospitalization, major surgery and/or immunosuppressive and broad-spectrum antibiotic therapy.

Authors+Show Affiliations

Servicio de Microbiología y Unidad de Investigación, Hospital Universitario La Paz, Paseo de la Castellana, Madrid, Spain.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19624502

Citation

Cendejas, E, et al. "Detection and Characterization of Enterobacteriaceae Producing Metallo-beta-lactamases in a Tertiary-care Hospital in Spain." Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, vol. 16, no. 2, 2010, pp. 181-3.
Cendejas E, Gómez-Gil R, Gómez-Sánchez P, et al. Detection and characterization of Enterobacteriaceae producing metallo-beta-lactamases in a tertiary-care hospital in Spain. Clin Microbiol Infect. 2010;16(2):181-3.
Cendejas, E., Gómez-Gil, R., Gómez-Sánchez, P., & Mingorance, J. (2010). Detection and characterization of Enterobacteriaceae producing metallo-beta-lactamases in a tertiary-care hospital in Spain. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 16(2), 181-3. https://doi.org/10.1111/j.1469-0691.2009.02888.x
Cendejas E, et al. Detection and Characterization of Enterobacteriaceae Producing Metallo-beta-lactamases in a Tertiary-care Hospital in Spain. Clin Microbiol Infect. 2010;16(2):181-3. PubMed PMID: 19624502.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Detection and characterization of Enterobacteriaceae producing metallo-beta-lactamases in a tertiary-care hospital in Spain. AU - Cendejas,E, AU - Gómez-Gil,R, AU - Gómez-Sánchez,P, AU - Mingorance,J, Y1 - 2009/07/14/ PY - 2009/7/24/entrez PY - 2009/7/25/pubmed PY - 2010/3/23/medline SP - 181 EP - 3 JF - Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases JO - Clin Microbiol Infect VL - 16 IS - 2 N2 - Carbapenem-resistant or intermediate (MIC >or=1 mg/L) clinical isolates (n = 12) of three species of Enterobacteriaceae (Klebsiella pneumoniae, Klebsiella oxytoca and Escherichia coli) were characterized. The isolates harboured integrons containing the VIM-1 metallo-beta-lactamase gene together with other resistance gene cassettes. In particular, the CTX-M-2 gene was detected in four of the K. pneumoniae isolates. The patient population was mostly paediatric and characterized by severe underlying illnesses that involved long-term hospitalization, major surgery and/or immunosuppressive and broad-spectrum antibiotic therapy. SN - 1469-0691 UR - https://www.unboundmedicine.com/medline/citation/19624502/Detection_and_characterization_of_Enterobacteriaceae_producing_metallo_beta_lactamases_in_a_tertiary_care_hospital_in_Spain_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1198-743X(14)61543-3 DB - PRIME DP - Unbound Medicine ER -