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Linking definition of childhood and adolescent obesity to current health outcomes.
Int J Pediatr Obes. 2010 Apr; 5(2):130-42.IJ

Abstract

OBJECTIVE

To evaluate the ability of body mass index (BMI) and fat location indices to predict clustering of risk factors for cardiovascular and metabolic disorders in children and adolescents.

METHODS

A total of 2 835 children in the 3(rd) (8.2-11.3 years) and 9(th) (14-17.3 years) grade were randomly selected from Denmark, Estonia and Portugal. BMI, waist-circumference (WC) and waist-to-height ratio (WHt) were evaluated. Children were considered to have clustering of risk factors if >or=3 risk factors were present: high levels of total cholesterol, triglyceride, glucose, insulin, blood pressure and low levels of aerobic fitness and HDL-C. The diagnostic accuracy for detecting children at risk was evaluated through receiver operating characteristics analyses, performed separately for boys and girls in the four age groups: 8.2-9.5; 9.5-11.3; 14.0-15.5 and 15.5-17.3 years. Cut-offs producing equal sensitivity and specificity and minimizing misclassifications were derived. Children were classified as overweight and obese based on BMI cut-offs producing equal sensitivity and specificity and minimizing misclassifications, respectively.

RESULTS

The diagnostic accuracy for identifying children at risk, measured by the area under the curve (AUC), of all anthropometric indices were significantly higher than what would be expected by chance (AUC >0.5). BMI cut-offs for overweight had similar sensitivity (58.8% to 75%) and specificity (60% to 71.2%) values, whereas specificity (94.4% to 99.7%) was markedly higher than sensitivity (9.3% to 52.6%) for obesity cut-offs.

CONCLUSION

BMI, WC and WHt can be used to identify children and adolescents aged 8.2-17.3 years with a clustering of cardiovascular risk factors.

Authors+Show Affiliations

Research Unit for Dietary Studies, Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark. AAR@ipm.regionh.dkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19626520

Citation

Adegboye, A R A., et al. "Linking Definition of Childhood and Adolescent Obesity to Current Health Outcomes." International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity, vol. 5, no. 2, 2010, pp. 130-42.
Adegboye AR, Andersen LB, Froberg K, et al. Linking definition of childhood and adolescent obesity to current health outcomes. Int J Pediatr Obes. 2010;5(2):130-42.
Adegboye, A. R., Andersen, L. B., Froberg, K., Sardinha, L. B., & Heitmann, B. L. (2010). Linking definition of childhood and adolescent obesity to current health outcomes. International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity, 5(2), 130-42. https://doi.org/10.3109/17477160903111730
Adegboye AR, et al. Linking Definition of Childhood and Adolescent Obesity to Current Health Outcomes. Int J Pediatr Obes. 2010;5(2):130-42. PubMed PMID: 19626520.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Linking definition of childhood and adolescent obesity to current health outcomes. AU - Adegboye,A R A, AU - Andersen,L B, AU - Froberg,K, AU - Sardinha,L B, AU - Heitmann,B L, PY - 2009/7/24/entrez PY - 2009/7/25/pubmed PY - 2010/9/24/medline SP - 130 EP - 42 JF - International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity JO - Int J Pediatr Obes VL - 5 IS - 2 N2 - OBJECTIVE: To evaluate the ability of body mass index (BMI) and fat location indices to predict clustering of risk factors for cardiovascular and metabolic disorders in children and adolescents. METHODS: A total of 2 835 children in the 3(rd) (8.2-11.3 years) and 9(th) (14-17.3 years) grade were randomly selected from Denmark, Estonia and Portugal. BMI, waist-circumference (WC) and waist-to-height ratio (WHt) were evaluated. Children were considered to have clustering of risk factors if >or=3 risk factors were present: high levels of total cholesterol, triglyceride, glucose, insulin, blood pressure and low levels of aerobic fitness and HDL-C. The diagnostic accuracy for detecting children at risk was evaluated through receiver operating characteristics analyses, performed separately for boys and girls in the four age groups: 8.2-9.5; 9.5-11.3; 14.0-15.5 and 15.5-17.3 years. Cut-offs producing equal sensitivity and specificity and minimizing misclassifications were derived. Children were classified as overweight and obese based on BMI cut-offs producing equal sensitivity and specificity and minimizing misclassifications, respectively. RESULTS: The diagnostic accuracy for identifying children at risk, measured by the area under the curve (AUC), of all anthropometric indices were significantly higher than what would be expected by chance (AUC >0.5). BMI cut-offs for overweight had similar sensitivity (58.8% to 75%) and specificity (60% to 71.2%) values, whereas specificity (94.4% to 99.7%) was markedly higher than sensitivity (9.3% to 52.6%) for obesity cut-offs. CONCLUSION: BMI, WC and WHt can be used to identify children and adolescents aged 8.2-17.3 years with a clustering of cardiovascular risk factors. SN - 1747-7174 UR - https://www.unboundmedicine.com/medline/citation/19626520/Linking_definition_of_childhood_and_adolescent_obesity_to_current_health_outcomes_ L2 - https://doi.org/10.3109/17477160903111730 DB - PRIME DP - Unbound Medicine ER -