Tags

Type your tag names separated by a space and hit enter

Public health projects for preventing the recurrence of neural tube defects in the United States.
Birth Defects Res A Clin Mol Teratol. 2009 Nov; 85(11):935-8.BD

Abstract

BACKGROUND

The recurrence risk for neural tube defects (NTDs) in subsequent pregnancies is approximately 3%, or 40 times the background risk. Prevention projects target these high-risk women to increase their folic acid consumption during the periconceptional period, a behavior which decreases their recurrence risk by at least 85%. This study surveyed birth defect surveillance programs to assess their NTD recurrence prevention activities and to identify components of intervention projects that might be implemented in states with limited resources.

METHODS

In 2005, the National Birth Defects Prevention Network developed and distributed an online survey to primary state birth defects surveillance contacts for the purpose of gathering information on NTD recurrence prevention activities in the United States.

RESULTS

Responses came from 37 contacts in 34 states and Puerto Rico. There were 13 active NTD recurrence prevention projects, four past projects, and three planned projects. Fifteen past and present projects recommended that women with a prior NTD-affected birth take 4.0 mg of folic acid daily, and four projects provided folic acid to the women. Reasons given for not having an NTD recurrence prevention project included staffing limitations (53%), lack of funds (47%), lack of priority (18%), and confidentiality/privacy concerns (6%).

CONCLUSIONS

Only 15 states and Puerto Rico had or were planning NTD recurrence prevention projects. An NTD recurrence prevention project using minimal resources should consist of timely case ascertainment, educational materials, and mechanisms for disseminating these materials.

Authors+Show Affiliations

JC Self Research Institute of Human Genetics, Greenwood Genetic Center, 113 Gregor Mendel Circle, Greenwood, SC 29646, USA. julianne@ggc.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

19626670

Citation

Collins, Julianne S., et al. "Public Health Projects for Preventing the Recurrence of Neural Tube Defects in the United States." Birth Defects Research. Part A, Clinical and Molecular Teratology, vol. 85, no. 11, 2009, pp. 935-8.
Collins JS, Canfield MA, Pearson K, et al. Public health projects for preventing the recurrence of neural tube defects in the United States. Birth Defects Res A Clin Mol Teratol. 2009;85(11):935-8.
Collins, J. S., Canfield, M. A., Pearson, K., Kirby, R. S., Case, A. P., Mai, C. T., Major, J., & Mulinare, J. (2009). Public health projects for preventing the recurrence of neural tube defects in the United States. Birth Defects Research. Part A, Clinical and Molecular Teratology, 85(11), 935-8. https://doi.org/10.1002/bdra.20619
Collins JS, et al. Public Health Projects for Preventing the Recurrence of Neural Tube Defects in the United States. Birth Defects Res A Clin Mol Teratol. 2009;85(11):935-8. PubMed PMID: 19626670.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Public health projects for preventing the recurrence of neural tube defects in the United States. AU - Collins,Julianne S, AU - Canfield,Mark A, AU - Pearson,Kay, AU - Kirby,Russell S, AU - Case,Amy P, AU - Mai,Cara T, AU - Major,Judy, AU - Mulinare,Joe, AU - ,, PY - 2009/7/24/entrez PY - 2009/7/25/pubmed PY - 2010/1/26/medline SP - 935 EP - 8 JF - Birth defects research. Part A, Clinical and molecular teratology JO - Birth Defects Res A Clin Mol Teratol VL - 85 IS - 11 N2 - BACKGROUND: The recurrence risk for neural tube defects (NTDs) in subsequent pregnancies is approximately 3%, or 40 times the background risk. Prevention projects target these high-risk women to increase their folic acid consumption during the periconceptional period, a behavior which decreases their recurrence risk by at least 85%. This study surveyed birth defect surveillance programs to assess their NTD recurrence prevention activities and to identify components of intervention projects that might be implemented in states with limited resources. METHODS: In 2005, the National Birth Defects Prevention Network developed and distributed an online survey to primary state birth defects surveillance contacts for the purpose of gathering information on NTD recurrence prevention activities in the United States. RESULTS: Responses came from 37 contacts in 34 states and Puerto Rico. There were 13 active NTD recurrence prevention projects, four past projects, and three planned projects. Fifteen past and present projects recommended that women with a prior NTD-affected birth take 4.0 mg of folic acid daily, and four projects provided folic acid to the women. Reasons given for not having an NTD recurrence prevention project included staffing limitations (53%), lack of funds (47%), lack of priority (18%), and confidentiality/privacy concerns (6%). CONCLUSIONS: Only 15 states and Puerto Rico had or were planning NTD recurrence prevention projects. An NTD recurrence prevention project using minimal resources should consist of timely case ascertainment, educational materials, and mechanisms for disseminating these materials. SN - 1542-0760 UR - https://www.unboundmedicine.com/medline/citation/19626670/Public_health_projects_for_preventing_the_recurrence_of_neural_tube_defects_in_the_United_States_ L2 - https://doi.org/10.1002/bdra.20619 DB - PRIME DP - Unbound Medicine ER -