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beta-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term.
Appetite 2009; 53(3):338-44A

Abstract

Dietary fibre consumption may help to control appetite and to reduce calorie intake. Underlying molecular mechanisms were not fully investigated. The aim of this study was to evaluate the effect of barley beta-glucans on short-term appetite and on satiety-related hormones in healthy subjects. Fourteen volunteers were selected and randomly assigned to have isocaloric breakfasts including a 3% beta-glucan-enriched bread (betaGB) or a control bread (CB). Post-breakfast individual self-records of appetite ratings and measure of calorie intake at an ad libitum lunch as well as measure of blood glucose, insulin, ghrelin and PYY concentrations, were performed. betaGB determined a significant higher reduction of hunger and increase of fullness and satiety than CB. Accordingly, a 19% reduction of energy intake at lunch subsequent to betaGB consumption compared to CB, was recorded. A 23% lower AUC(60-180) of plasma ghrelin and a 16% higher total AUC of PYY response after betaGB than CB consumption, independent from insulin response, was found. Glucose response was also blunted by betaGB vs CB. Barley beta-glucans were able to control appetite in the short term by modulating sensations and reducing energy intake. Data suggested for the first time that satiety effect of beta-glucans are mediated by ghrelin and PYY.

Authors+Show Affiliations

Department of Food Science, University of Naples, via Università 100, 80055 Portici (NA), Italy. paola.vitaglione@unina.it

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19631705

Citation

Vitaglione, Paola, et al. "Beta-Glucan-enriched Bread Reduces Energy Intake and Modifies Plasma Ghrelin and Peptide YY Concentrations in the Short Term." Appetite, vol. 53, no. 3, 2009, pp. 338-44.
Vitaglione P, Lumaga RB, Stanzione A, et al. Beta-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term. Appetite. 2009;53(3):338-44.
Vitaglione, P., Lumaga, R. B., Stanzione, A., Scalfi, L., & Fogliano, V. (2009). Beta-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term. Appetite, 53(3), pp. 338-44. doi:10.1016/j.appet.2009.07.013.
Vitaglione P, et al. Beta-Glucan-enriched Bread Reduces Energy Intake and Modifies Plasma Ghrelin and Peptide YY Concentrations in the Short Term. Appetite. 2009;53(3):338-44. PubMed PMID: 19631705.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - beta-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term. AU - Vitaglione,Paola, AU - Lumaga,Roberta Barone, AU - Stanzione,Antonio, AU - Scalfi,Luca, AU - Fogliano,Vincenzo, Y1 - 2009/07/23/ PY - 2009/04/09/received PY - 2009/07/08/revised PY - 2009/07/15/accepted PY - 2009/7/28/entrez PY - 2009/7/28/pubmed PY - 2010/2/18/medline SP - 338 EP - 44 JF - Appetite JO - Appetite VL - 53 IS - 3 N2 - Dietary fibre consumption may help to control appetite and to reduce calorie intake. Underlying molecular mechanisms were not fully investigated. The aim of this study was to evaluate the effect of barley beta-glucans on short-term appetite and on satiety-related hormones in healthy subjects. Fourteen volunteers were selected and randomly assigned to have isocaloric breakfasts including a 3% beta-glucan-enriched bread (betaGB) or a control bread (CB). Post-breakfast individual self-records of appetite ratings and measure of calorie intake at an ad libitum lunch as well as measure of blood glucose, insulin, ghrelin and PYY concentrations, were performed. betaGB determined a significant higher reduction of hunger and increase of fullness and satiety than CB. Accordingly, a 19% reduction of energy intake at lunch subsequent to betaGB consumption compared to CB, was recorded. A 23% lower AUC(60-180) of plasma ghrelin and a 16% higher total AUC of PYY response after betaGB than CB consumption, independent from insulin response, was found. Glucose response was also blunted by betaGB vs CB. Barley beta-glucans were able to control appetite in the short term by modulating sensations and reducing energy intake. Data suggested for the first time that satiety effect of beta-glucans are mediated by ghrelin and PYY. SN - 1095-8304 UR - https://www.unboundmedicine.com/medline/citation/19631705/beta_Glucan_enriched_bread_reduces_energy_intake_and_modifies_plasma_ghrelin_and_peptide_YY_concentrations_in_the_short_term_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0195-6663(09)00579-0 DB - PRIME DP - Unbound Medicine ER -