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Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article.
J Neurosurg Pediatr. 2009 Aug; 4(2):113-7.JN

Abstract

OBJECT

The purpose of this study was to describe the surgical treatment and outcomes of patients with intracranial extension of juvenile nasopharyngeal angiofibroma (JNA).

METHODS

Twenty-one patients who underwent operations for JNAs between 1994 and 2008 were enrolled in the study. Seven patients (33%) had intracranial tumor extension. The middle cranial fossa and cavernous sinus were involved in 4 patients who underwent operations via the combined infratemporal fossa-midfacial degloving approach. The anterior skull base was involved in 3 patients who underwent the subcranialmidfacial degloving approach.

RESULTS

Complete tumor removal was achieved in all patients. Postoperative complications included 1 case of soft-tissue infection. None of the patients had tumor recurrence after a mean follow-up of 42 months (range 29-85 months). No adjuvant therapy was required in any patient.

CONCLUSIONS

Combined approaches can be used effectively for treatment of JNAs with intracranial extension without the need for adjuvant therapy.

Authors+Show Affiliations

Skull Base Surgery Service, Tel-Aviv University, Tel-Aviv, Israel.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19645542

Citation

Margalit, Nevo, et al. "Surgical Treatment of Juvenile Nasopharyngeal Angiofibroma With Intracranial Extension. Clinical Article." Journal of Neurosurgery. Pediatrics, vol. 4, no. 2, 2009, pp. 113-7.
Margalit N, Wasserzug O, De-Row A, et al. Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article. J Neurosurg Pediatr. 2009;4(2):113-7.
Margalit, N., Wasserzug, O., De-Row, A., Abergel, A., Fliss, D. M., & Gil, Z. (2009). Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article. Journal of Neurosurgery. Pediatrics, 4(2), 113-7. https://doi.org/10.3171/2009.4.PEDS08321
Margalit N, et al. Surgical Treatment of Juvenile Nasopharyngeal Angiofibroma With Intracranial Extension. Clinical Article. J Neurosurg Pediatr. 2009;4(2):113-7. PubMed PMID: 19645542.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article. AU - Margalit,Nevo, AU - Wasserzug,Oshri, AU - De-Row,Ari, AU - Abergel,Avraham, AU - Fliss,Dan M, AU - Gil,Ziv, PY - 2009/8/4/entrez PY - 2009/8/4/pubmed PY - 2009/10/9/medline SP - 113 EP - 7 JF - Journal of neurosurgery. Pediatrics JO - J Neurosurg Pediatr VL - 4 IS - 2 N2 - OBJECT: The purpose of this study was to describe the surgical treatment and outcomes of patients with intracranial extension of juvenile nasopharyngeal angiofibroma (JNA). METHODS: Twenty-one patients who underwent operations for JNAs between 1994 and 2008 were enrolled in the study. Seven patients (33%) had intracranial tumor extension. The middle cranial fossa and cavernous sinus were involved in 4 patients who underwent operations via the combined infratemporal fossa-midfacial degloving approach. The anterior skull base was involved in 3 patients who underwent the subcranialmidfacial degloving approach. RESULTS: Complete tumor removal was achieved in all patients. Postoperative complications included 1 case of soft-tissue infection. None of the patients had tumor recurrence after a mean follow-up of 42 months (range 29-85 months). No adjuvant therapy was required in any patient. CONCLUSIONS: Combined approaches can be used effectively for treatment of JNAs with intracranial extension without the need for adjuvant therapy. SN - 1933-0707 UR - https://www.unboundmedicine.com/medline/citation/19645542/Surgical_treatment_of_juvenile_nasopharyngeal_angiofibroma_with_intracranial_extension__Clinical_article_ L2 - https://thejns.org/doi/10.3171/2009.4.PEDS08321 DB - PRIME DP - Unbound Medicine ER -