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Comparison of patients with juvenile psoriatic arthritis and nonpsoriatic juvenile idiopathic arthritis: how different are they?
J Rheumatol. 2009 Sep; 36(9):2033-41.JR

Abstract

OBJECTIVE

To compare the clinical features and outcome between patients with juvenile psoriatic arthritis (JPsA) and non-JPsA juvenile idiopathic arthritis (JIA).

METHODS

Fifty-three children with JPsA, 32 with < 5 joints in the first 6 months of disease (oligo-JPsA) and 21 (> or = 5 joints) polyarticular-onset (poly-JPsA) were compared to 53 patients with JIA who were matched by sex, age, date of diagnosis, and articular onset pattern.

RESULTS

There was no difference in the percentage of patients between the oligoarticular groups who developed extended oligoarthritis or in the percentage of patients who were positive for antinuclear antibodies. The only differences were that 25% of patients with oligo-JPsA had dactylitis compared to 0% of patients with oligo-JIA (p < 0.01) and 50% had nail pitting as compared to 18.7% (p < 0.05). In polyarticular patients the percentages with dactylitis were similar (19% vs 38%; p = 0.25). The frequency of uveitis was identical in the oligoarticular patients but a higher rate was seen in poly-JPsA compared to poly-JIA (23.8% vs 0%; p = 0.02), while contractures were more frequent in poly-JIA compared to poly-JPsA during the course of the illness (47.6% vs 14.3%; p = 0.03) but not at last followup (14.3% vs 4.7%; p = 0.6). At last followup the mean Childhood Health Assessment Questionnaire scores were similar in both the polyarticular and oligoarticular groups.

CONCLUSION

There were only a few differences between patients with JPsA and JIA regarding disease onset, disease course, and outcome. We suggest that large, longterm prospective studies are required to accurately determine whether subdividing JIA according to psoriasis is worthwhile.

Authors+Show Affiliations

Division of Rheumatology, Hospital for Sick Children, Toronto, Ontario, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

19648305

Citation

Butbul, Yonatan Aviel, et al. "Comparison of Patients With Juvenile Psoriatic Arthritis and Nonpsoriatic Juvenile Idiopathic Arthritis: How Different Are They?" The Journal of Rheumatology, vol. 36, no. 9, 2009, pp. 2033-41.
Butbul YA, Tyrrell PN, Schneider R, et al. Comparison of patients with juvenile psoriatic arthritis and nonpsoriatic juvenile idiopathic arthritis: how different are they? J Rheumatol. 2009;36(9):2033-41.
Butbul, Y. A., Tyrrell, P. N., Schneider, R., Dhillon, S., Feldman, B. M., Laxer, R. M., Saurenmann, R. K., Spiegel, L., Cameron, B., Tse, S. M., & Silverman, E. D. (2009). Comparison of patients with juvenile psoriatic arthritis and nonpsoriatic juvenile idiopathic arthritis: how different are they? The Journal of Rheumatology, 36(9), 2033-41. https://doi.org/10.3899/jrheum.080674
Butbul YA, et al. Comparison of Patients With Juvenile Psoriatic Arthritis and Nonpsoriatic Juvenile Idiopathic Arthritis: How Different Are They. J Rheumatol. 2009;36(9):2033-41. PubMed PMID: 19648305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of patients with juvenile psoriatic arthritis and nonpsoriatic juvenile idiopathic arthritis: how different are they? AU - Butbul,Yonatan Aviel, AU - Tyrrell,Pascal N, AU - Schneider,Rayfel, AU - Dhillon,Sandeep, AU - Feldman,Brian M, AU - Laxer,Ronald M, AU - Saurenmann,Rotraud K, AU - Spiegel,Lynn, AU - Cameron,Bonnie, AU - Tse,Shirley M, AU - Silverman,Earl D, Y1 - 2009/07/31/ PY - 2009/8/4/entrez PY - 2009/8/4/pubmed PY - 2009/11/17/medline SP - 2033 EP - 41 JF - The Journal of rheumatology JO - J Rheumatol VL - 36 IS - 9 N2 - OBJECTIVE: To compare the clinical features and outcome between patients with juvenile psoriatic arthritis (JPsA) and non-JPsA juvenile idiopathic arthritis (JIA). METHODS: Fifty-three children with JPsA, 32 with < 5 joints in the first 6 months of disease (oligo-JPsA) and 21 (> or = 5 joints) polyarticular-onset (poly-JPsA) were compared to 53 patients with JIA who were matched by sex, age, date of diagnosis, and articular onset pattern. RESULTS: There was no difference in the percentage of patients between the oligoarticular groups who developed extended oligoarthritis or in the percentage of patients who were positive for antinuclear antibodies. The only differences were that 25% of patients with oligo-JPsA had dactylitis compared to 0% of patients with oligo-JIA (p < 0.01) and 50% had nail pitting as compared to 18.7% (p < 0.05). In polyarticular patients the percentages with dactylitis were similar (19% vs 38%; p = 0.25). The frequency of uveitis was identical in the oligoarticular patients but a higher rate was seen in poly-JPsA compared to poly-JIA (23.8% vs 0%; p = 0.02), while contractures were more frequent in poly-JIA compared to poly-JPsA during the course of the illness (47.6% vs 14.3%; p = 0.03) but not at last followup (14.3% vs 4.7%; p = 0.6). At last followup the mean Childhood Health Assessment Questionnaire scores were similar in both the polyarticular and oligoarticular groups. CONCLUSION: There were only a few differences between patients with JPsA and JIA regarding disease onset, disease course, and outcome. We suggest that large, longterm prospective studies are required to accurately determine whether subdividing JIA according to psoriasis is worthwhile. SN - 0315-162X UR - https://www.unboundmedicine.com/medline/citation/19648305/Comparison_of_patients_with_juvenile_psoriatic_arthritis_and_nonpsoriatic_juvenile_idiopathic_arthritis:_how_different_are_they L2 - http://www.jrheum.org/cgi/pmidlookup?view=long&amp;pmid=19648305 DB - PRIME DP - Unbound Medicine ER -