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Palindromic rheumatism: longterm outcomes of 60 patients diagnosed in 1967-84.
J Rheumatol. 2009 Sep; 36(9):1873-5.JR

Abstract

OBJECTIVE

To study longterm outcomes of 60 patients with palindromic rheumatism (PR) diagnosed in 1967-1984.

METHODS

A cohort of patients with PR was identified in Jyväskylä Central Hospital in 1967-84, and reexamined in 1984-86. In 2006, medical records of the patients were reviewed to analyze the proportion of patients who had developed chronic rheumatoid arthritis (RA), had joint replacement surgery, or had died. Patients' health status was reviewed by mail questionnaires including functional status on the Health Assessment Questionnaire (HAQ), pain, and the number of painful joints.

RESULTS

Forty patients developed chronic RA over the observation period of over 20 years, among whom 38 patients within 10 years and 2 patients after 10 years. Twenty-four patients had died by 2006, 17 (42%) in the RA group and 7 (35%) in the non-RA group. Nine patients, all in the RA group (23%), had received 1 or more joint replacements. The mean HAQ score was 0.57 in the non-RA survivors (mean age 70 yrs), compared to 0.89 in the RA group (mean age 66 yrs) (p = 0.020, adjusted for age). Pain scores and the number of painful joints were similar between the groups.

CONCLUSION

Two-thirds of the patients with PR developed chronic arthritis. The risk to develop chronic arthritis remained over 10 years. The RA group was characterized with functional declines and having joint replacements as longterm outcomes of the disease.

Authors+Show Affiliations

Jyväskylä Central Hospital, Jyväskylä, Finland. tuulikki_sokka@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19648311

Citation

Koskinen, Essi, et al. "Palindromic Rheumatism: Longterm Outcomes of 60 Patients Diagnosed in 1967-84." The Journal of Rheumatology, vol. 36, no. 9, 2009, pp. 1873-5.
Koskinen E, Hannonen P, Sokka T. Palindromic rheumatism: longterm outcomes of 60 patients diagnosed in 1967-84. J Rheumatol. 2009;36(9):1873-5.
Koskinen, E., Hannonen, P., & Sokka, T. (2009). Palindromic rheumatism: longterm outcomes of 60 patients diagnosed in 1967-84. The Journal of Rheumatology, 36(9), 1873-5. https://doi.org/10.3899/jrheum.090025
Koskinen E, Hannonen P, Sokka T. Palindromic Rheumatism: Longterm Outcomes of 60 Patients Diagnosed in 1967-84. J Rheumatol. 2009;36(9):1873-5. PubMed PMID: 19648311.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Palindromic rheumatism: longterm outcomes of 60 patients diagnosed in 1967-84. AU - Koskinen,Essi, AU - Hannonen,Pekka, AU - Sokka,Tuulikki, Y1 - 2009/07/31/ PY - 2009/8/4/entrez PY - 2009/8/4/pubmed PY - 2009/11/17/medline SP - 1873 EP - 5 JF - The Journal of rheumatology JO - J Rheumatol VL - 36 IS - 9 N2 - OBJECTIVE: To study longterm outcomes of 60 patients with palindromic rheumatism (PR) diagnosed in 1967-1984. METHODS: A cohort of patients with PR was identified in Jyväskylä Central Hospital in 1967-84, and reexamined in 1984-86. In 2006, medical records of the patients were reviewed to analyze the proportion of patients who had developed chronic rheumatoid arthritis (RA), had joint replacement surgery, or had died. Patients' health status was reviewed by mail questionnaires including functional status on the Health Assessment Questionnaire (HAQ), pain, and the number of painful joints. RESULTS: Forty patients developed chronic RA over the observation period of over 20 years, among whom 38 patients within 10 years and 2 patients after 10 years. Twenty-four patients had died by 2006, 17 (42%) in the RA group and 7 (35%) in the non-RA group. Nine patients, all in the RA group (23%), had received 1 or more joint replacements. The mean HAQ score was 0.57 in the non-RA survivors (mean age 70 yrs), compared to 0.89 in the RA group (mean age 66 yrs) (p = 0.020, adjusted for age). Pain scores and the number of painful joints were similar between the groups. CONCLUSION: Two-thirds of the patients with PR developed chronic arthritis. The risk to develop chronic arthritis remained over 10 years. The RA group was characterized with functional declines and having joint replacements as longterm outcomes of the disease. SN - 0315-162X UR - https://www.unboundmedicine.com/medline/citation/19648311/Palindromic_rheumatism:_longterm_outcomes_of_60_patients_diagnosed_in_1967_84_ L2 - http://www.jrheum.org/cgi/pmidlookup?view=long&pmid=19648311 DB - PRIME DP - Unbound Medicine ER -