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Prehospital fibrinolytic therapy followed by urgent percutaneous coronary intervention in patients with ST-elevation myocardial infarction.
Future Cardiol. 2009 Jul; 5(4):403-11.FC

Abstract

In patients with ST-segment elevation myocardial infarction (STEMI) the shorter the reperfusion time, the better the outcome is, regardless of the reperfusion method. Effective, early and rapid reperfusion is the most important goal in the treatment of patients with STEMI. In majority cases of STEMI, transport or transfer to a percutaneous coronary intervention (PCI)-capable center will occur, sometimes bypassing the closest hospital facilities that are not PCI centers. The timely optimal reperfusion strategy might be a prehospital initiated pharmacological reperfusion with subsequent PCI. Reduced-dose prehospital fibrinolysis allows safe transport of STEMI patients to PCI centers for urgent culprit artery PCI, and may be a superior approach compared with transporting patients to the closest non-PCI hospital for fibrinolytic therapy. In this review we will discuss the evidence regarding reperfusion strategies in STEMI patients.

Authors+Show Affiliations

Division of Cardiology, University of Texas Health Science Center at Houston TX, USA. ekrem.yeter@uth.tmc.eduNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

19656064

Citation

Yeter, Ekrem, and Ali E. Denktas. "Prehospital Fibrinolytic Therapy Followed By Urgent Percutaneous Coronary Intervention in Patients With ST-elevation Myocardial Infarction." Future Cardiology, vol. 5, no. 4, 2009, pp. 403-11.
Yeter E, Denktas AE. Prehospital fibrinolytic therapy followed by urgent percutaneous coronary intervention in patients with ST-elevation myocardial infarction. Future Cardiol. 2009;5(4):403-11.
Yeter, E., & Denktas, A. E. (2009). Prehospital fibrinolytic therapy followed by urgent percutaneous coronary intervention in patients with ST-elevation myocardial infarction. Future Cardiology, 5(4), 403-11. https://doi.org/10.2217/fca.09.22
Yeter E, Denktas AE. Prehospital Fibrinolytic Therapy Followed By Urgent Percutaneous Coronary Intervention in Patients With ST-elevation Myocardial Infarction. Future Cardiol. 2009;5(4):403-11. PubMed PMID: 19656064.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prehospital fibrinolytic therapy followed by urgent percutaneous coronary intervention in patients with ST-elevation myocardial infarction. AU - Yeter,Ekrem, AU - Denktas,Ali E, PY - 2009/8/7/entrez PY - 2009/8/7/pubmed PY - 2009/10/30/medline SP - 403 EP - 11 JF - Future cardiology JO - Future Cardiol VL - 5 IS - 4 N2 - In patients with ST-segment elevation myocardial infarction (STEMI) the shorter the reperfusion time, the better the outcome is, regardless of the reperfusion method. Effective, early and rapid reperfusion is the most important goal in the treatment of patients with STEMI. In majority cases of STEMI, transport or transfer to a percutaneous coronary intervention (PCI)-capable center will occur, sometimes bypassing the closest hospital facilities that are not PCI centers. The timely optimal reperfusion strategy might be a prehospital initiated pharmacological reperfusion with subsequent PCI. Reduced-dose prehospital fibrinolysis allows safe transport of STEMI patients to PCI centers for urgent culprit artery PCI, and may be a superior approach compared with transporting patients to the closest non-PCI hospital for fibrinolytic therapy. In this review we will discuss the evidence regarding reperfusion strategies in STEMI patients. SN - 1744-8298 UR - https://www.unboundmedicine.com/medline/citation/19656064/Prehospital_fibrinolytic_therapy_followed_by_urgent_percutaneous_coronary_intervention_in_patients_with_ST_elevation_myocardial_infarction_ L2 - http://www.futuremedicine.com/doi/full/10.2217/fca.09.22?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -