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[Mechanisms of reconsolidation and extinction of fear memory].
Nihon Shinkei Seishin Yakurigaku Zasshi. 2009 Jun; 29(3):125-33.NS

Abstract

Reconsolidation and extinction of fear memories are induced by re-exposure to the conditioned stimulus (CS) but they appear to be opposite processes; as the fear memory is maintained or inhibited through reconsolidation and extinction, respectively. More importantly, reconsolidation and extinction are thought to be potential targets for the treatment of Post Traumatic Stress Disorder (PTSD). From this view, it is important to understand mechanisms by which reactivated fear memories are reconsolidated or extinguished. Here, we review processes for fear memory regulation including consolidation, reconsolidation and extinction, and discuss implications of fear memory regulation with PTSD.

Authors+Show Affiliations

Kida S
Department of Bioscience, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, 156-8502 Japan. kida@nodai.ac.jp
Fukushima H
No affiliation info available
Mamiya N
No affiliation info available

MeSH

Extinction, PsychologicalFearHumansMemoryStress Disorders, Post-Traumatic

Pub Type(s)

English Abstract
Journal Article
Review

Language

jpn

PubMed ID

19663263

Citation

Kida, Satoshi, et al. "[Mechanisms of Reconsolidation and Extinction of Fear Memory]." Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology, vol. 29, no. 3, 2009, pp. 125-33.
Kida S, Fukushima H, Mamiya N. [Mechanisms of reconsolidation and extinction of fear memory]. Nihon Shinkei Seishin Yakurigaku Zasshi. 2009;29(3):125-33.
Kida, S., Fukushima, H., & Mamiya, N. (2009). [Mechanisms of reconsolidation and extinction of fear memory]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology, 29(3), 125-33.
Kida S, Fukushima H, Mamiya N. [Mechanisms of Reconsolidation and Extinction of Fear Memory]. Nihon Shinkei Seishin Yakurigaku Zasshi. 2009;29(3):125-33. PubMed PMID: 19663263.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Mechanisms of reconsolidation and extinction of fear memory]. AU - Kida,Satoshi, AU - Fukushima,Hotaka, AU - Mamiya,Nori, PY - 2009/8/12/entrez PY - 2009/8/12/pubmed PY - 2009/9/4/medline SP - 125 EP - 33 JF - Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology JO - Nihon Shinkei Seishin Yakurigaku Zasshi VL - 29 IS - 3 N2 - Reconsolidation and extinction of fear memories are induced by re-exposure to the conditioned stimulus (CS) but they appear to be opposite processes; as the fear memory is maintained or inhibited through reconsolidation and extinction, respectively. More importantly, reconsolidation and extinction are thought to be potential targets for the treatment of Post Traumatic Stress Disorder (PTSD). From this view, it is important to understand mechanisms by which reactivated fear memories are reconsolidated or extinguished. Here, we review processes for fear memory regulation including consolidation, reconsolidation and extinction, and discuss implications of fear memory regulation with PTSD. SN - 1340-2544 UR - https://www.unboundmedicine.com/medline/citation/19663263/[Mechanisms_of_reconsolidation_and_extinction_of_fear_memory]_ L2 - https://medlineplus.gov/memory.html DB - PRIME DP - Unbound Medicine ER -