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Potential of Ginkgo biloba L. leaves in the management of hyperglycemia and hypertension using in vitro models.
Bioresour Technol. 2009 Dec; 100(24):6599-609.BT

Abstract

Leaves from four different Ginkgo biloba L. trees (1 and 2--females; 3 and 4--males), grown at the same conditions, were collected during a period of 5 months (from June to October, 2007). Water and 12% ethanol extracts were analyzed for total phenolics content, antioxidant activity, phenolic profile, and the potential in vitro inhibitory effects on alpha-amylase, alpha-glucosidase, and Angiotensin I-Converting Enzyme (ACE) enzymes related to the management of diabetes and hypertension. The results indicated a significant difference among the trees in all functional benefits evaluated in the leaf extracts and also found important seasonal variation related to the same functional parameters. In general, the aqueous extracts had higher total phenolic content than the ethanolic extracts. Also, no correlation was found between total phenolics and antioxidant activity. In relation to the ACE inhibition, only ethanolic extracts had inhibitory activity.

Authors+Show Affiliations

Laboratório de Química, Bioquímica e Biologia Molecular de Alimentos, Departamento de Alimentos e Nutrição Experimental, FCF, Universidade de São Paulo, Av. Prof. Lineu Prestes 580, Bloco 14, 05508-900 São Paulo, SP, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19665890

Citation

Pinto, Marcia Da Silva, et al. "Potential of Ginkgo Biloba L. Leaves in the Management of Hyperglycemia and Hypertension Using in Vitro Models." Bioresource Technology, vol. 100, no. 24, 2009, pp. 6599-609.
Pinto Mda S, Kwon YI, Apostolidis E, et al. Potential of Ginkgo biloba L. leaves in the management of hyperglycemia and hypertension using in vitro models. Bioresour Technol. 2009;100(24):6599-609.
Pinto, M. d. a. . S., Kwon, Y. I., Apostolidis, E., Lajolo, F. M., Genovese, M. I., & Shetty, K. (2009). Potential of Ginkgo biloba L. leaves in the management of hyperglycemia and hypertension using in vitro models. Bioresource Technology, 100(24), 6599-609. https://doi.org/10.1016/j.biortech.2009.07.021
Pinto Mda S, et al. Potential of Ginkgo Biloba L. Leaves in the Management of Hyperglycemia and Hypertension Using in Vitro Models. Bioresour Technol. 2009;100(24):6599-609. PubMed PMID: 19665890.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Potential of Ginkgo biloba L. leaves in the management of hyperglycemia and hypertension using in vitro models. AU - Pinto,Marcia Da Silva, AU - Kwon,Young-In, AU - Apostolidis,Emmanouil, AU - Lajolo,Franco Maria, AU - Genovese,Maria Inés, AU - Shetty,Kalidas, Y1 - 2009/08/08/ PY - 2008/04/10/received PY - 2009/07/07/revised PY - 2009/07/07/accepted PY - 2009/8/12/entrez PY - 2009/8/12/pubmed PY - 2009/12/16/medline SP - 6599 EP - 609 JF - Bioresource technology JO - Bioresour Technol VL - 100 IS - 24 N2 - Leaves from four different Ginkgo biloba L. trees (1 and 2--females; 3 and 4--males), grown at the same conditions, were collected during a period of 5 months (from June to October, 2007). Water and 12% ethanol extracts were analyzed for total phenolics content, antioxidant activity, phenolic profile, and the potential in vitro inhibitory effects on alpha-amylase, alpha-glucosidase, and Angiotensin I-Converting Enzyme (ACE) enzymes related to the management of diabetes and hypertension. The results indicated a significant difference among the trees in all functional benefits evaluated in the leaf extracts and also found important seasonal variation related to the same functional parameters. In general, the aqueous extracts had higher total phenolic content than the ethanolic extracts. Also, no correlation was found between total phenolics and antioxidant activity. In relation to the ACE inhibition, only ethanolic extracts had inhibitory activity. SN - 1873-2976 UR - https://www.unboundmedicine.com/medline/citation/19665890/Potential_of_Ginkgo_biloba_L__leaves_in_the_management_of_hyperglycemia_and_hypertension_using_in_vitro_models_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0960-8524(09)00890-6 DB - PRIME DP - Unbound Medicine ER -