Tags

Type your tag names separated by a space and hit enter

MRI of the knee at 3T: first clinical results with an isotropic PDfs-weighted 3D-TSE-sequence.
Invest Radiol. 2009 Sep; 44(9):585-97.IR

Abstract

PURPOSE

To clinically evaluate MRI of the knee using a highly resolved isotropic fat-saturated (fs) proton-density weighted 3D-TSE-sequence (SPACE) at 3T.

MATERIALS AND METHODS

Imaging was performed on a 3T-scanner (Magnetom TRIO). For technical evaluation, sagittally orientated SPACE-datasets (repetition-time [TR], 1200 milliseconds/[TE], 30 milliseconds/voxel-size, 0.5 mm3/acquisition time, 10:35 minutes) were acquired from the dominant knee of 10 healthy volunteers. In the 3 major anatomic planes, 0.5, 1, and 2 mm thick reconstructions were performed. Signal-to-noise (SNR), SNR-efficiency, contrast-to-noise (CNR) ratios, and anatomic detail visualization were compared with a state-of-the-art 2D-TSE-sequence in 3 imaging planes (TR, 3200 milliseconds/TE, 30 milliseconds/acquisition time, 12:34 minutes). Sixty patients with cartilage and meniscus pathologies were examined with these techniques. Patient SPACE-datasets were assessed in 1-mm thick reconstructions. Arthroscopical correlation was available for 18 patients. Lesion detection and diagnostic confidence were assessed by 2 radiologists independently. Statistical analysis was performed using 95% confidence intervals, Wilcoxon signed rank tests, and Weighted-kappa.

RESULTS

SNR-efficiency of SPACE was 4 to 5 times higher than for 2D-TSE-sequences. SNR and CNR of 1-mm thick SPACE-reconstructions were comparable to 2D-TSE-sequences and provided superior visualization of small structures such as meniscal roots.Correlation with arthroscopy did not show significant differences between 2D- and 3D-sequences. One reader detected significantly more cartilage abnormalities with the 2D-TSE-sequence (131 vs. 151, P = 0.04), probably because of an unfamiliar fluid/cartilage contrast. Diagnostic confidence was significantly higher for meniscus abnormalities for SPACE for 1 reader. Intersequence-correlation was excellent (kappa = 0.82-0.92). Interreader-correlation was good to excellent (kappa = 0.71-0.80), intrareader-correlation was excellent (kappa = 0.90-0.92) for both sequences.

CONCLUSIONS

Time-efficient 3D-TSE-imaging of the knee at 3T is feasible with adequate SNR and CNR and excellent anatomic detail visualization. Detection and visualization of meniscus and cartilage pathologies is comparable to standard 2D-TSE-sequences. 3D-TSE-sequences with consecutive multiplanar reconstruction may become a valuable component of future knee-MRI protocols.

Authors+Show Affiliations

Department of Clinical Radiology, University Hospitals Munich, Campus Grosshadern, Munich, Germany. mike.notohamiprodjo@med.uni-muenchen.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

19668001

Citation

Notohamiprodjo, Mike, et al. "MRI of the Knee at 3T: First Clinical Results With an Isotropic PDfs-weighted 3D-TSE-sequence." Investigative Radiology, vol. 44, no. 9, 2009, pp. 585-97.
Notohamiprodjo M, Horng A, Pietschmann MF, et al. MRI of the knee at 3T: first clinical results with an isotropic PDfs-weighted 3D-TSE-sequence. Invest Radiol. 2009;44(9):585-97.
Notohamiprodjo, M., Horng, A., Pietschmann, M. F., Müller, P. E., Horger, W., Park, J., Crispin, A., del Olmo, J. R., Weckbach, S., Herrmann, K. A., Reiser, M. F., & Glaser, C. (2009). MRI of the knee at 3T: first clinical results with an isotropic PDfs-weighted 3D-TSE-sequence. Investigative Radiology, 44(9), 585-97. https://doi.org/10.1097/RLI.0b013e3181b4c1a1
Notohamiprodjo M, et al. MRI of the Knee at 3T: First Clinical Results With an Isotropic PDfs-weighted 3D-TSE-sequence. Invest Radiol. 2009;44(9):585-97. PubMed PMID: 19668001.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - MRI of the knee at 3T: first clinical results with an isotropic PDfs-weighted 3D-TSE-sequence. AU - Notohamiprodjo,Mike, AU - Horng,Annie, AU - Pietschmann,Matthias F, AU - Müller,Peter E, AU - Horger,Wilhelm, AU - Park,Jaeseok, AU - Crispin,Alexander, AU - del Olmo,José Raya Garcia, AU - Weckbach,Sabine, AU - Herrmann,Karin A, AU - Reiser,Maximilian F, AU - Glaser,Christian, PY - 2009/8/12/entrez PY - 2009/8/12/pubmed PY - 2009/11/6/medline SP - 585 EP - 97 JF - Investigative radiology JO - Invest Radiol VL - 44 IS - 9 N2 - PURPOSE: To clinically evaluate MRI of the knee using a highly resolved isotropic fat-saturated (fs) proton-density weighted 3D-TSE-sequence (SPACE) at 3T. MATERIALS AND METHODS: Imaging was performed on a 3T-scanner (Magnetom TRIO). For technical evaluation, sagittally orientated SPACE-datasets (repetition-time [TR], 1200 milliseconds/[TE], 30 milliseconds/voxel-size, 0.5 mm3/acquisition time, 10:35 minutes) were acquired from the dominant knee of 10 healthy volunteers. In the 3 major anatomic planes, 0.5, 1, and 2 mm thick reconstructions were performed. Signal-to-noise (SNR), SNR-efficiency, contrast-to-noise (CNR) ratios, and anatomic detail visualization were compared with a state-of-the-art 2D-TSE-sequence in 3 imaging planes (TR, 3200 milliseconds/TE, 30 milliseconds/acquisition time, 12:34 minutes). Sixty patients with cartilage and meniscus pathologies were examined with these techniques. Patient SPACE-datasets were assessed in 1-mm thick reconstructions. Arthroscopical correlation was available for 18 patients. Lesion detection and diagnostic confidence were assessed by 2 radiologists independently. Statistical analysis was performed using 95% confidence intervals, Wilcoxon signed rank tests, and Weighted-kappa. RESULTS: SNR-efficiency of SPACE was 4 to 5 times higher than for 2D-TSE-sequences. SNR and CNR of 1-mm thick SPACE-reconstructions were comparable to 2D-TSE-sequences and provided superior visualization of small structures such as meniscal roots.Correlation with arthroscopy did not show significant differences between 2D- and 3D-sequences. One reader detected significantly more cartilage abnormalities with the 2D-TSE-sequence (131 vs. 151, P = 0.04), probably because of an unfamiliar fluid/cartilage contrast. Diagnostic confidence was significantly higher for meniscus abnormalities for SPACE for 1 reader. Intersequence-correlation was excellent (kappa = 0.82-0.92). Interreader-correlation was good to excellent (kappa = 0.71-0.80), intrareader-correlation was excellent (kappa = 0.90-0.92) for both sequences. CONCLUSIONS: Time-efficient 3D-TSE-imaging of the knee at 3T is feasible with adequate SNR and CNR and excellent anatomic detail visualization. Detection and visualization of meniscus and cartilage pathologies is comparable to standard 2D-TSE-sequences. 3D-TSE-sequences with consecutive multiplanar reconstruction may become a valuable component of future knee-MRI protocols. SN - 1536-0210 UR - https://www.unboundmedicine.com/medline/citation/19668001/MRI_of_the_knee_at_3T:_first_clinical_results_with_an_isotropic_PDfs_weighted_3D_TSE_sequence_ L2 - https://doi.org/10.1097/RLI.0b013e3181b4c1a1 DB - PRIME DP - Unbound Medicine ER -