Tags

Type your tag names separated by a space and hit enter

Fatigue in Japanese patients with Parkinson's disease: a study using Parkinson fatigue scale.
Mov Disord. 2009 Oct 15; 24(13):1977-83.MD

Abstract

The objective of this multicenter cross-sectional study was to determine the prevalence of fatigue and factors contributing to it in a large sample of Japanese patients with Parkinson's disease (PD). We used the 16-item Parkinson Fatigue Scale (PFS-16), which was designed to assess fatigue exclusively associated with PD. We carried out this study using PFS-16, the Unified Parkinson's Disease Rating Scale, Zung's Self-Rating Depression Scale, Parkinson's Disease Sleep Scale (PDSS), and the PD quality of life (QOL) scale (PDQ-39) by interview using questionnaires and physical examination by neurologists in 361 nondemented PD patients. Fatigue (an average PFS score of 3.3 or greater) was revealed in 151 patients (41.8%). Multiple logistic regression analysis indicated that the significant independent variables related to the presence of fatigue were the scores of PDSS and PDQ-39. Depression score was not a significant contributing factor. Our study revealed that the prevalence of fatigue in Japanese PD patients is as high as that in Western countries, and that fatigue is a relatively independent symptom, although sleep disturbance may be associated with fatigue. Since fatigue is significantly related to QOL reduction, therapeutic interventions including treatment of sleep disturbance are important.

Authors+Show Affiliations

Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410-2295, Japan. sgz02202@nifty.ne.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19672993

Citation

Okuma, Yasuyuki, et al. "Fatigue in Japanese Patients With Parkinson's Disease: a Study Using Parkinson Fatigue Scale." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 24, no. 13, 2009, pp. 1977-83.
Okuma Y, Kamei S, Morita A, et al. Fatigue in Japanese patients with Parkinson's disease: a study using Parkinson fatigue scale. Mov Disord. 2009;24(13):1977-83.
Okuma, Y., Kamei, S., Morita, A., Yoshii, F., Yamamoto, T., Hashimoto, S., Utsumi, H., Hatano, T., Hattori, N., Matsumura, M., Takahashi, K., Nogawa, S., Watanabe, Y., Miyamoto, T., Miyamoto, M., & Hirata, K. (2009). Fatigue in Japanese patients with Parkinson's disease: a study using Parkinson fatigue scale. Movement Disorders : Official Journal of the Movement Disorder Society, 24(13), 1977-83. https://doi.org/10.1002/mds.22731
Okuma Y, et al. Fatigue in Japanese Patients With Parkinson's Disease: a Study Using Parkinson Fatigue Scale. Mov Disord. 2009 Oct 15;24(13):1977-83. PubMed PMID: 19672993.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fatigue in Japanese patients with Parkinson's disease: a study using Parkinson fatigue scale. AU - Okuma,Yasuyuki, AU - Kamei,Satoshi, AU - Morita,Akihiko, AU - Yoshii,Fumihito, AU - Yamamoto,Toshimasa, AU - Hashimoto,Shiori, AU - Utsumi,Hiroya, AU - Hatano,Taku, AU - Hattori,Nobutaka, AU - Matsumura,Miyuki, AU - Takahashi,Kazushi, AU - Nogawa,Shigeru, AU - Watanabe,Yuka, AU - Miyamoto,Tomoyuki, AU - Miyamoto,Masayuki, AU - Hirata,Koichi, PY - 2009/8/13/entrez PY - 2009/8/13/pubmed PY - 2010/1/12/medline SP - 1977 EP - 83 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 24 IS - 13 N2 - The objective of this multicenter cross-sectional study was to determine the prevalence of fatigue and factors contributing to it in a large sample of Japanese patients with Parkinson's disease (PD). We used the 16-item Parkinson Fatigue Scale (PFS-16), which was designed to assess fatigue exclusively associated with PD. We carried out this study using PFS-16, the Unified Parkinson's Disease Rating Scale, Zung's Self-Rating Depression Scale, Parkinson's Disease Sleep Scale (PDSS), and the PD quality of life (QOL) scale (PDQ-39) by interview using questionnaires and physical examination by neurologists in 361 nondemented PD patients. Fatigue (an average PFS score of 3.3 or greater) was revealed in 151 patients (41.8%). Multiple logistic regression analysis indicated that the significant independent variables related to the presence of fatigue were the scores of PDSS and PDQ-39. Depression score was not a significant contributing factor. Our study revealed that the prevalence of fatigue in Japanese PD patients is as high as that in Western countries, and that fatigue is a relatively independent symptom, although sleep disturbance may be associated with fatigue. Since fatigue is significantly related to QOL reduction, therapeutic interventions including treatment of sleep disturbance are important. SN - 1531-8257 UR - https://www.unboundmedicine.com/medline/citation/19672993/Fatigue_in_Japanese_patients_with_Parkinson's_disease:_a_study_using_Parkinson_fatigue_scale_ L2 - https://doi.org/10.1002/mds.22731 DB - PRIME DP - Unbound Medicine ER -