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Tardive dyskinesia in a patient treated with quetiapine.
World J Biol Psychiatry. 2009; 10(1):54-7.WJ

Abstract

Quetiapine is an atypical antipsychotic that is believed to have a low D2 binding affinity in striatal and extrastriatal regions. We report the case of a female patient with the diagnosis of schizoaffective disorder (using DSM-IV-TR criteria) who initially received amisulpride for 3 months, discontinued gradually because of persistent and distressing extra-pyramidal symptoms, and who developed tardive dyskinesia 3 months later after the initiation of quetiapine. A trial with ziprasidone resulted in a further worsening of tardive dyskinesia symptoms. A further trial with aripiprazole, improved her tardive dyskinesia symptoms. Although, it is under consideration the possibility that the improvement could have been due to the discontinuation of quetiapine, we conclude that aripiprazole improved the TD symptoms.

Authors+Show Affiliations

Second Department of Psychiatry, University of Athens, Medical School, "Attikon" General Hospital, Greece.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19673087

Citation

Rizos, Emmanouil, et al. "Tardive Dyskinesia in a Patient Treated With Quetiapine." The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry, vol. 10, no. 1, 2009, pp. 54-7.
Rizos E, Douzenis A, Gournellis R, et al. Tardive dyskinesia in a patient treated with quetiapine. World J Biol Psychiatry. 2009;10(1):54-7.
Rizos, E., Douzenis, A., Gournellis, R., Christodoulou, C., & Lykouras, L. P. (2009). Tardive dyskinesia in a patient treated with quetiapine. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry, 10(1), 54-7.
Rizos E, et al. Tardive Dyskinesia in a Patient Treated With Quetiapine. World J Biol Psychiatry. 2009;10(1):54-7. PubMed PMID: 19673087.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tardive dyskinesia in a patient treated with quetiapine. AU - Rizos,Emmanouil, AU - Douzenis,Athanassios, AU - Gournellis,Rossetos, AU - Christodoulou,Christos, AU - Lykouras,Lefteris P, PY - 2009/8/13/entrez PY - 2009/8/13/pubmed PY - 2009/8/20/medline SP - 54 EP - 7 JF - The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry JO - World J Biol Psychiatry VL - 10 IS - 1 N2 - Quetiapine is an atypical antipsychotic that is believed to have a low D2 binding affinity in striatal and extrastriatal regions. We report the case of a female patient with the diagnosis of schizoaffective disorder (using DSM-IV-TR criteria) who initially received amisulpride for 3 months, discontinued gradually because of persistent and distressing extra-pyramidal symptoms, and who developed tardive dyskinesia 3 months later after the initiation of quetiapine. A trial with ziprasidone resulted in a further worsening of tardive dyskinesia symptoms. A further trial with aripiprazole, improved her tardive dyskinesia symptoms. Although, it is under consideration the possibility that the improvement could have been due to the discontinuation of quetiapine, we conclude that aripiprazole improved the TD symptoms. SN - 1562-2975 UR - https://www.unboundmedicine.com/medline/citation/19673087/Tardive_dyskinesia_in_a_patient_treated_with_quetiapine_ L2 - https://www.tandfonline.com/doi/full/10.1080/15622970701362550 DB - PRIME DP - Unbound Medicine ER -