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CSWS-related autistic regression versus autistic regression without CSWS.
Epilepsia. 2009 Aug; 50 Suppl 7:18-20.E

Abstract

Continuous spike-waves during slow-wave sleep (CSWS) and Landau-Kleffner syndrome (LKS) are two clinical epileptic syndromes that are associated with the electroencephalography (EEG) pattern of electrical status epilepticus during slow wave sleep (ESES). Autistic regression occurs in approximately 30% of children with autism and is associated with an epileptiform EEG in approximately 20%. The behavioral phenotypes of CSWS, LKS, and autistic regression overlap. However, the differences in age of regression, degree and type of regression, and frequency of epilepsy and EEG abnormalities suggest that these are distinct phenotypes. CSWS with autistic regression is rare, as is autistic regression associated with ESES. The pathophysiology and as such the treatment implications for children with CSWS and autistic regression are distinct from those with autistic regression without CSWS.

Authors+Show Affiliations

Miami Children's Hospital, Miami Children's Hospital Dan Marino Center, 2900 South Commerce Parkway, Weston, Florida, U.S.A. tuchman@att.net

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19682044

Citation

Tuchman, Roberto. "CSWS-related Autistic Regression Versus Autistic Regression Without CSWS." Epilepsia, vol. 50 Suppl 7, 2009, pp. 18-20.
Tuchman R. CSWS-related autistic regression versus autistic regression without CSWS. Epilepsia. 2009;50 Suppl 7:18-20.
Tuchman, R. (2009). CSWS-related autistic regression versus autistic regression without CSWS. Epilepsia, 50 Suppl 7, 18-20. https://doi.org/10.1111/j.1528-1167.2009.02212.x
Tuchman R. CSWS-related Autistic Regression Versus Autistic Regression Without CSWS. Epilepsia. 2009;50 Suppl 7:18-20. PubMed PMID: 19682044.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - CSWS-related autistic regression versus autistic regression without CSWS. A1 - Tuchman,Roberto, PY - 2009/8/18/entrez PY - 2009/8/18/pubmed PY - 2009/9/12/medline SP - 18 EP - 20 JF - Epilepsia JO - Epilepsia VL - 50 Suppl 7 N2 - Continuous spike-waves during slow-wave sleep (CSWS) and Landau-Kleffner syndrome (LKS) are two clinical epileptic syndromes that are associated with the electroencephalography (EEG) pattern of electrical status epilepticus during slow wave sleep (ESES). Autistic regression occurs in approximately 30% of children with autism and is associated with an epileptiform EEG in approximately 20%. The behavioral phenotypes of CSWS, LKS, and autistic regression overlap. However, the differences in age of regression, degree and type of regression, and frequency of epilepsy and EEG abnormalities suggest that these are distinct phenotypes. CSWS with autistic regression is rare, as is autistic regression associated with ESES. The pathophysiology and as such the treatment implications for children with CSWS and autistic regression are distinct from those with autistic regression without CSWS. SN - 1528-1167 UR - https://www.unboundmedicine.com/medline/citation/19682044/CSWS_related_autistic_regression_versus_autistic_regression_without_CSWS_ L2 - https://doi.org/10.1111/j.1528-1167.2009.02212.x DB - PRIME DP - Unbound Medicine ER -