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Cell based therapy for Duchenne muscular dystrophy.
J Cell Physiol. 2009 Dec; 221(3):526-34.JC

Abstract

Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy.

Authors+Show Affiliations

Stem Cell Laboratory, Department of Neurological Science, Centro Dino Ferrari, University of Milan, Fondazione IRCCS Policlinico Mangiagalli Regina Elena, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

19688776

Citation

Farini, Andrea, et al. "Cell Based Therapy for Duchenne Muscular Dystrophy." Journal of Cellular Physiology, vol. 221, no. 3, 2009, pp. 526-34.
Farini A, Razini P, Erratico S, et al. Cell based therapy for Duchenne muscular dystrophy. J Cell Physiol. 2009;221(3):526-34.
Farini, A., Razini, P., Erratico, S., Torrente, Y., & Meregalli, M. (2009). Cell based therapy for Duchenne muscular dystrophy. Journal of Cellular Physiology, 221(3), 526-34. https://doi.org/10.1002/jcp.21895
Farini A, et al. Cell Based Therapy for Duchenne Muscular Dystrophy. J Cell Physiol. 2009;221(3):526-34. PubMed PMID: 19688776.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cell based therapy for Duchenne muscular dystrophy. AU - Farini,Andrea, AU - Razini,Paola, AU - Erratico,Silvia, AU - Torrente,Yvan, AU - Meregalli,Mirella, PY - 2009/8/19/entrez PY - 2009/8/19/pubmed PY - 2009/11/17/medline SP - 526 EP - 34 JF - Journal of cellular physiology JO - J. Cell. Physiol. VL - 221 IS - 3 N2 - Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy. SN - 1097-4652 UR - https://www.unboundmedicine.com/medline/citation/19688776/Cell_based_therapy_for_Duchenne_muscular_dystrophy_ L2 - https://doi.org/10.1002/jcp.21895 DB - PRIME DP - Unbound Medicine ER -