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Association of white blood cell count and peripheral arterial disease in patients with and without traditional risk factors.
Angiology. 2010 May; 61(4):382-7.A

Abstract

Peripheral arterial disease (PAD) is an inflammatory process. The association between white blood cell (WBC) count and PAD in those with and without traditional risk factors is not clear. We examined data from the National Health and Nutrition Examination Survey (NHANES) 1999 to 2004. A total of 5260 participants were included. The result showed that the prevalence of PAD rose from 2.8% +/- 0.5% in the lowest quartile of plasma WBC count to 8.0% +/- 1.2% in the highest quartile. In subgroup analysis, the graded association between WBC count and PAD was significant in patients without hypertension, diabetes, smoking, chronic kidney disease (CKD), and in patients with or without hypercholesterolemia but not significant in patients with hypertension, smoking, diabetes, or CKD. In those without hypertension, diabetes, smoking, or CKD, the cutoff value for WBC count was 6.75 x 10(9)/L. We concluded that the positive association between WBC count and PAD can be demonstrated in this national survey.

Authors+Show Affiliations

Cardiovascular Center, National Taiwan University Hospital, Yun-Lin Branch, Douliou, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19689993

Citation

Chen, Jien-Jiun, et al. "Association of White Blood Cell Count and Peripheral Arterial Disease in Patients With and Without Traditional Risk Factors." Angiology, vol. 61, no. 4, 2010, pp. 382-7.
Chen JJ, Lin LY, Lee HH, et al. Association of white blood cell count and peripheral arterial disease in patients with and without traditional risk factors. Angiology. 2010;61(4):382-7.
Chen, J. J., Lin, L. Y., Lee, H. H., Lai, L. P., Lin, J. L., Huang, J. J., & Tseng, C. D. (2010). Association of white blood cell count and peripheral arterial disease in patients with and without traditional risk factors. Angiology, 61(4), 382-7. https://doi.org/10.1177/0003319709344575
Chen JJ, et al. Association of White Blood Cell Count and Peripheral Arterial Disease in Patients With and Without Traditional Risk Factors. Angiology. 2010;61(4):382-7. PubMed PMID: 19689993.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association of white blood cell count and peripheral arterial disease in patients with and without traditional risk factors. AU - Chen,Jien-Jiun, AU - Lin,Lian-Yu, AU - Lee,Hsiu-Hao, AU - Lai,Lin-Ping, AU - Lin,Jiunn-Lee, AU - Huang,Juey-Jen, AU - Tseng,Chuen-Den, Y1 - 2009/08/18/ PY - 2009/8/20/entrez PY - 2009/8/20/pubmed PY - 2010/7/16/medline SP - 382 EP - 7 JF - Angiology JO - Angiology VL - 61 IS - 4 N2 - Peripheral arterial disease (PAD) is an inflammatory process. The association between white blood cell (WBC) count and PAD in those with and without traditional risk factors is not clear. We examined data from the National Health and Nutrition Examination Survey (NHANES) 1999 to 2004. A total of 5260 participants were included. The result showed that the prevalence of PAD rose from 2.8% +/- 0.5% in the lowest quartile of plasma WBC count to 8.0% +/- 1.2% in the highest quartile. In subgroup analysis, the graded association between WBC count and PAD was significant in patients without hypertension, diabetes, smoking, chronic kidney disease (CKD), and in patients with or without hypercholesterolemia but not significant in patients with hypertension, smoking, diabetes, or CKD. In those without hypertension, diabetes, smoking, or CKD, the cutoff value for WBC count was 6.75 x 10(9)/L. We concluded that the positive association between WBC count and PAD can be demonstrated in this national survey. SN - 1940-1574 UR - https://www.unboundmedicine.com/medline/citation/19689993/Association_of_white_blood_cell_count_and_peripheral_arterial_disease_in_patients_with_and_without_traditional_risk_factors_ L2 - https://journals.sagepub.com/doi/10.1177/0003319709344575?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -