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Phenolic-linked variation in strawberry cultivars for potential dietary management of hyperglycemia and related complications of hypertension.
Bioresour Technol. 2010 Jan; 101(1):404-13.BT

Abstract

Fruit extracts of different strawberry cultivars were evaluated for their potential to contribute to the dietary management of hyperglycemia-linked to type 2 diabetes and related hypertension. In vitro inhibition of alpha-amylase, alpha-glucosidase, and angiotensin-1-converting enzyme (ACE) activity was evaluated using fruit extracts and correlated to phenolic content and antioxidant activity. There were significant differences between cultivars in both phenolic-linked antioxidant activity and inhibitory activity for the targeted disease relevant enzymes. Honeoye, Idea, and Jewel cultivars exhibited moderate alpha-amylase inhibition. Strawberry cultivars, in general, exhibited uniform alpha-glucosidase inhibition with Ovation having the highest inhibitory activity. Water extracts of Jewel and Ovation cultivars had moderate ACE inhibition compared to low inhibition observed in other cultivars. Strawberry cultivars with combined inhibitory potential against alpha-glucosidase and ACE and with moderate or low alpha-amylase inhibitory potential could be targeted for potential management of hyperglycemia-linked type 2 diabetes and related complication of hypertension.

Authors+Show Affiliations

Department of Plant, Soil, and Insect Sciences, University of Massachusetts, Amherst, MA 01003, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19695871

Citation

Cheplick, Susan, et al. "Phenolic-linked Variation in Strawberry Cultivars for Potential Dietary Management of Hyperglycemia and Related Complications of Hypertension." Bioresource Technology, vol. 101, no. 1, 2010, pp. 404-13.
Cheplick S, Kwon YI, Bhowmik P, et al. Phenolic-linked variation in strawberry cultivars for potential dietary management of hyperglycemia and related complications of hypertension. Bioresour Technol. 2010;101(1):404-13.
Cheplick, S., Kwon, Y. I., Bhowmik, P., & Shetty, K. (2010). Phenolic-linked variation in strawberry cultivars for potential dietary management of hyperglycemia and related complications of hypertension. Bioresource Technology, 101(1), 404-13. https://doi.org/10.1016/j.biortech.2009.07.068
Cheplick S, et al. Phenolic-linked Variation in Strawberry Cultivars for Potential Dietary Management of Hyperglycemia and Related Complications of Hypertension. Bioresour Technol. 2010;101(1):404-13. PubMed PMID: 19695871.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phenolic-linked variation in strawberry cultivars for potential dietary management of hyperglycemia and related complications of hypertension. AU - Cheplick,Susan, AU - Kwon,Young-In, AU - Bhowmik,Prasanta, AU - Shetty,Kalidas, Y1 - 2009/08/19/ PY - 2007/03/22/received PY - 2009/07/22/revised PY - 2009/07/23/accepted PY - 2009/8/22/entrez PY - 2009/8/22/pubmed PY - 2009/12/16/medline SP - 404 EP - 13 JF - Bioresource technology JO - Bioresour Technol VL - 101 IS - 1 N2 - Fruit extracts of different strawberry cultivars were evaluated for their potential to contribute to the dietary management of hyperglycemia-linked to type 2 diabetes and related hypertension. In vitro inhibition of alpha-amylase, alpha-glucosidase, and angiotensin-1-converting enzyme (ACE) activity was evaluated using fruit extracts and correlated to phenolic content and antioxidant activity. There were significant differences between cultivars in both phenolic-linked antioxidant activity and inhibitory activity for the targeted disease relevant enzymes. Honeoye, Idea, and Jewel cultivars exhibited moderate alpha-amylase inhibition. Strawberry cultivars, in general, exhibited uniform alpha-glucosidase inhibition with Ovation having the highest inhibitory activity. Water extracts of Jewel and Ovation cultivars had moderate ACE inhibition compared to low inhibition observed in other cultivars. Strawberry cultivars with combined inhibitory potential against alpha-glucosidase and ACE and with moderate or low alpha-amylase inhibitory potential could be targeted for potential management of hyperglycemia-linked type 2 diabetes and related complication of hypertension. SN - 1873-2976 UR - https://www.unboundmedicine.com/medline/citation/19695871/Phenolic_linked_variation_in_strawberry_cultivars_for_potential_dietary_management_of_hyperglycemia_and_related_complications_of_hypertension_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0960-8524(09)00969-9 DB - PRIME DP - Unbound Medicine ER -