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Comorbidity of depressive and anxiety disorders for older Americans in the national comorbidity survey-replication.
Am J Geriatr Psychiatry. 2009 Sep; 17(9):782-92.AJ

Abstract

OBJECTIVE

To identify age differences in the 12-month and lifetime comorbidity of depressive and anxiety disorders for adults (18-64 years) compared with older adults (65 years and older) in a nationally representative sample of community-dwelling adults in the United States.

DESIGN

Cross-sectional epidemiologic study, using data from the National Comorbidity Survey-Replication public use dataset.

SETTING

Community-based epidemiologic survey.

PARTICIPANTS

Representative national sample of community-dwelling adults in the United States.

MEASUREMENTS

The World Health Organization Composite International Diagnostic Interview was used to assess Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition psychiatric disorders.

RESULTS

More than half of respondents with a 12-month major depressive disorder (MDD) had a comorbid anxiety disorder or dysthymia (18-64 years = 60.6%; 65 years and older = 51.8%). High rates of MDD were also found for those with anxiety disorders across both age groups, highest in the 18-64 years group for generalized anxiety disorder (28.5%) and highest in the 65 years and older group for panic disorder (36.7%). Age group did not predict 12-month diagnosis of a comorbid anxiety disorder among those with a depressive disorder in multivariate logistic regression. Onset of anxiety disorders preceded onset of depressive disorders for most older adults (77.6%).

CONCLUSIONS

Depressive and anxiety disorders frequently cooccurred in this representative sample of community-dwelling adults. Older adults experienced comorbidity to a similar extent as younger adults, suggesting high rates of comorbidity across the lifespan.

Authors+Show Affiliations

Department of Medical Psychology, Amsterdam Medical Center, University of Amsterdam, Amsterdam, The Netherlands.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19700950

Citation

King-Kallimanis, Bellinda, et al. "Comorbidity of Depressive and Anxiety Disorders for Older Americans in the National Comorbidity Survey-replication." The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry, vol. 17, no. 9, 2009, pp. 782-92.
King-Kallimanis B, Gum AM, Kohn R. Comorbidity of depressive and anxiety disorders for older Americans in the national comorbidity survey-replication. Am J Geriatr Psychiatry. 2009;17(9):782-92.
King-Kallimanis, B., Gum, A. M., & Kohn, R. (2009). Comorbidity of depressive and anxiety disorders for older Americans in the national comorbidity survey-replication. The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry, 17(9), 782-92. https://doi.org/10.1097/JGP.0b013e3181ad4d17
King-Kallimanis B, Gum AM, Kohn R. Comorbidity of Depressive and Anxiety Disorders for Older Americans in the National Comorbidity Survey-replication. Am J Geriatr Psychiatry. 2009;17(9):782-92. PubMed PMID: 19700950.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comorbidity of depressive and anxiety disorders for older Americans in the national comorbidity survey-replication. AU - King-Kallimanis,Bellinda, AU - Gum,Amber M, AU - Kohn,Robert, PY - 2009/8/25/entrez PY - 2009/8/25/pubmed PY - 2009/10/21/medline SP - 782 EP - 92 JF - The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry JO - Am J Geriatr Psychiatry VL - 17 IS - 9 N2 - OBJECTIVE: To identify age differences in the 12-month and lifetime comorbidity of depressive and anxiety disorders for adults (18-64 years) compared with older adults (65 years and older) in a nationally representative sample of community-dwelling adults in the United States. DESIGN: Cross-sectional epidemiologic study, using data from the National Comorbidity Survey-Replication public use dataset. SETTING: Community-based epidemiologic survey. PARTICIPANTS: Representative national sample of community-dwelling adults in the United States. MEASUREMENTS: The World Health Organization Composite International Diagnostic Interview was used to assess Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition psychiatric disorders. RESULTS: More than half of respondents with a 12-month major depressive disorder (MDD) had a comorbid anxiety disorder or dysthymia (18-64 years = 60.6%; 65 years and older = 51.8%). High rates of MDD were also found for those with anxiety disorders across both age groups, highest in the 18-64 years group for generalized anxiety disorder (28.5%) and highest in the 65 years and older group for panic disorder (36.7%). Age group did not predict 12-month diagnosis of a comorbid anxiety disorder among those with a depressive disorder in multivariate logistic regression. Onset of anxiety disorders preceded onset of depressive disorders for most older adults (77.6%). CONCLUSIONS: Depressive and anxiety disorders frequently cooccurred in this representative sample of community-dwelling adults. Older adults experienced comorbidity to a similar extent as younger adults, suggesting high rates of comorbidity across the lifespan. SN - 1545-7214 UR - https://www.unboundmedicine.com/medline/citation/19700950/Comorbidity_of_depressive_and_anxiety_disorders_for_older_Americans_in_the_national_comorbidity_survey_replication_ L2 - https://linkinghub.elsevier.com/retrieve/pii/00019442-200909000-00009 DB - PRIME DP - Unbound Medicine ER -