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Pharmacotherapy of cryptococcosis.
Expert Opin Pharmacother. 2009 Oct; 10(15):2433-43.EO

Abstract

Cryptococcus neoformans is an opportunistic fungal pathogen that causes central nervous system and pulmonary disease among immunocompromised patients. Recent studies highlight the high incidence of cryptococcosis among patients in certain resource-poor areas, where there is also a high incidence of AIDS. Despite the availability of antifungal agents with anticryptococcal activity, the mortality and treatment-failure rates associated with cryptococcosis remain unacceptably high. This article reviews current treatment strategies and the basis for these strategies, as well as prospects for future approaches to the treatment of cryptococcosis.

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Publisher Full Text

Authors+Show Affiliations

Ritter M
Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA.
Goldman DL
No affiliation info available

MeSH

AIDS-Related Opportunistic InfectionsAcquired Immunodeficiency SyndromeAnimalsAntifungal AgentsClinical Trials as TopicCryptococcosisCryptococcus neoformansHumansImmunocompromised HostOpportunistic Infections

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19708853

Citation

Ritter, Michele, and David L. Goldman. "Pharmacotherapy of Cryptococcosis." Expert Opinion On Pharmacotherapy, vol. 10, no. 15, 2009, pp. 2433-43.
Ritter M, Goldman DL. Pharmacotherapy of cryptococcosis. Expert Opin Pharmacother. 2009;10(15):2433-43.
Ritter, M., & Goldman, D. L. (2009). Pharmacotherapy of cryptococcosis. Expert Opinion On Pharmacotherapy, 10(15), 2433-43. https://doi.org/10.1517/14656560903200642
Ritter M, Goldman DL. Pharmacotherapy of Cryptococcosis. Expert Opin Pharmacother. 2009;10(15):2433-43. PubMed PMID: 19708853.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pharmacotherapy of cryptococcosis. AU - Ritter,Michele, AU - Goldman,David L, PY - 2009/8/28/entrez PY - 2009/8/28/pubmed PY - 2009/11/18/medline SP - 2433 EP - 43 JF - Expert opinion on pharmacotherapy JO - Expert Opin Pharmacother VL - 10 IS - 15 N2 - Cryptococcus neoformans is an opportunistic fungal pathogen that causes central nervous system and pulmonary disease among immunocompromised patients. Recent studies highlight the high incidence of cryptococcosis among patients in certain resource-poor areas, where there is also a high incidence of AIDS. Despite the availability of antifungal agents with anticryptococcal activity, the mortality and treatment-failure rates associated with cryptococcosis remain unacceptably high. This article reviews current treatment strategies and the basis for these strategies, as well as prospects for future approaches to the treatment of cryptococcosis. SN - 1744-7666 UR - https://www.unboundmedicine.com/medline/citation/19708853/Pharmacotherapy_of_cryptococcosis_ L2 - https://www.tandfonline.com/doi/full/10.1517/14656560903200642 DB - PRIME DP - Unbound Medicine ER -