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[Targeted UVB-308 nm (NUVB) therapy with excimer laser in the treatment of atopic dermatitis and other inflammatory dermatoses].
Hautarzt. 2009 Nov; 60(11):898-906.H

Abstract

UVB 311 nm phototherapy (NUVB) is used successfully in the treatment of psoriasis or atopic dermatitis and is often chosen as "first-line" therapy. In a prospective study we investigated the efficacy of the targeted UVB 308 phototherapy by excimer laser in the treatment of 57 patients with localized, mild therapy-resistant atopic dermatitis. We achieved a complete remission (CR) in nearly 85% and a partial remission (PR) in 15% after 10 treatments during 6-8 weeks in all patients. A mean reduction in patient-reported pruritus was one hallmark after 3-4 treatments. 48 other patients with lichen simplex chronicus Vidal, nodular prurigo, granuloma anulare, alopezia areata (AA) and lichen ruber planus were also treated by targeted NUVB. We found higher rates of CR and PR only in patients with AA and in patients with oral Lichen ruber mucosae. These results and the systematically reviewing of the current medical literature shows that targeted NUVB by excimer laser cannot be successfully transferred for all inflammatory skin diseases. In particular, Excimer UVB treatment expands the therapeutic options in patients with localized and therapy-resistant atopic dermatitis enormously.

Authors+Show Affiliations

Haut- und Allergieklinik, Klinikum Hanau GmbH, 63450 Hanau.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

19711024

Citation

Wollenschläger, I, et al. "[Targeted UVB-308 Nm (NUVB) Therapy With Excimer Laser in the Treatment of Atopic Dermatitis and Other Inflammatory Dermatoses]." Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, vol. 60, no. 11, 2009, pp. 898-906.
Wollenschläger I, Hermann J, Ockenfels HM. [Targeted UVB-308 nm (NUVB) therapy with excimer laser in the treatment of atopic dermatitis and other inflammatory dermatoses]. Hautarzt. 2009;60(11):898-906.
Wollenschläger, I., Hermann, J., & Ockenfels, H. M. (2009). [Targeted UVB-308 nm (NUVB) therapy with excimer laser in the treatment of atopic dermatitis and other inflammatory dermatoses]. Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, 60(11), 898-906. https://doi.org/10.1007/s00105-009-1828-8
Wollenschläger I, Hermann J, Ockenfels HM. [Targeted UVB-308 Nm (NUVB) Therapy With Excimer Laser in the Treatment of Atopic Dermatitis and Other Inflammatory Dermatoses]. Hautarzt. 2009;60(11):898-906. PubMed PMID: 19711024.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Targeted UVB-308 nm (NUVB) therapy with excimer laser in the treatment of atopic dermatitis and other inflammatory dermatoses]. AU - Wollenschläger,I, AU - Hermann,J, AU - Ockenfels,H M, PY - 2009/8/28/entrez PY - 2009/8/28/pubmed PY - 2010/4/9/medline SP - 898 EP - 906 JF - Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete JO - Hautarzt VL - 60 IS - 11 N2 - UVB 311 nm phototherapy (NUVB) is used successfully in the treatment of psoriasis or atopic dermatitis and is often chosen as "first-line" therapy. In a prospective study we investigated the efficacy of the targeted UVB 308 phototherapy by excimer laser in the treatment of 57 patients with localized, mild therapy-resistant atopic dermatitis. We achieved a complete remission (CR) in nearly 85% and a partial remission (PR) in 15% after 10 treatments during 6-8 weeks in all patients. A mean reduction in patient-reported pruritus was one hallmark after 3-4 treatments. 48 other patients with lichen simplex chronicus Vidal, nodular prurigo, granuloma anulare, alopezia areata (AA) and lichen ruber planus were also treated by targeted NUVB. We found higher rates of CR and PR only in patients with AA and in patients with oral Lichen ruber mucosae. These results and the systematically reviewing of the current medical literature shows that targeted NUVB by excimer laser cannot be successfully transferred for all inflammatory skin diseases. In particular, Excimer UVB treatment expands the therapeutic options in patients with localized and therapy-resistant atopic dermatitis enormously. SN - 1432-1173 UR - https://www.unboundmedicine.com/medline/citation/19711024/[Targeted_UVB_308_nm__NUVB__therapy_with_excimer_laser_in_the_treatment_of_atopic_dermatitis_and_other_inflammatory_dermatoses]_ L2 - https://dx.doi.org/10.1007/s00105-009-1828-8 DB - PRIME DP - Unbound Medicine ER -