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Diagnosis and surgical management of spontaneous hepatic rupture associated with HELLP syndrome.
J Surg Educ. 2009 May-Jun; 66(3):163-7.JS

Abstract

Spontaneous hepatic rupture with hemoperitoneum is an uncommon but devastating complication of hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. Although the syndrome has been considered a variant of preeclampsia/eclampsia, its pathogenesis is not completely understood. Hepatic rupture increases the perinatal and maternal morbidity and mortality. This report describes 3 cases of extensive spontaneous hepatic rupture in pregnant women with HELLP syndrome. Early diagnosis and adequate tertiary management of this rare but life-threatening condition reduce the high maternal and newborn mortality.

Authors+Show Affiliations

Intensive Care Unit, Mitera Hospital of Athens, Greece.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19712916

Citation

Pavlis, Theodoros, et al. "Diagnosis and Surgical Management of Spontaneous Hepatic Rupture Associated With HELLP Syndrome." Journal of Surgical Education, vol. 66, no. 3, 2009, pp. 163-7.
Pavlis T, Aloizos S, Aravosita P, et al. Diagnosis and surgical management of spontaneous hepatic rupture associated with HELLP syndrome. J Surg Educ. 2009;66(3):163-7.
Pavlis, T., Aloizos, S., Aravosita, P., Mystakelli, C., Petrochilou, D., Dimopoulos, N., & Gourgiotis, S. (2009). Diagnosis and surgical management of spontaneous hepatic rupture associated with HELLP syndrome. Journal of Surgical Education, 66(3), 163-7. https://doi.org/10.1016/j.jsurg.2009.04.001
Pavlis T, et al. Diagnosis and Surgical Management of Spontaneous Hepatic Rupture Associated With HELLP Syndrome. J Surg Educ. 2009 May-Jun;66(3):163-7. PubMed PMID: 19712916.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis and surgical management of spontaneous hepatic rupture associated with HELLP syndrome. AU - Pavlis,Theodoros, AU - Aloizos,Stavros, AU - Aravosita,Paraskevi, AU - Mystakelli,Christina, AU - Petrochilou,Dimitra, AU - Dimopoulos,Nikitas, AU - Gourgiotis,Stavros, PY - 2009/02/17/received PY - 2009/03/23/revised PY - 2009/04/06/accepted PY - 2009/8/29/entrez PY - 2009/8/29/pubmed PY - 2009/12/16/medline SP - 163 EP - 7 JF - Journal of surgical education JO - J Surg Educ VL - 66 IS - 3 N2 - Spontaneous hepatic rupture with hemoperitoneum is an uncommon but devastating complication of hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. Although the syndrome has been considered a variant of preeclampsia/eclampsia, its pathogenesis is not completely understood. Hepatic rupture increases the perinatal and maternal morbidity and mortality. This report describes 3 cases of extensive spontaneous hepatic rupture in pregnant women with HELLP syndrome. Early diagnosis and adequate tertiary management of this rare but life-threatening condition reduce the high maternal and newborn mortality. SN - 1878-7452 UR - https://www.unboundmedicine.com/medline/citation/19712916/Diagnosis_and_surgical_management_of_spontaneous_hepatic_rupture_associated_with_HELLP_syndrome_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1931-7204(09)00061-0 DB - PRIME DP - Unbound Medicine ER -