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Prevalence of alcohol consumption and risk of ocular diseases in a general population: the Beijing Eye Study.
Ophthalmology 2009; 116(10):1872-9O

Abstract

OBJECTIVE

To examine the associations between alcohol consumption and ocular diseases in the adult population of mainland China.

DESIGN

Population-based study.

PARTICIPANTS

The Beijing Eye Study, performed in 2001, included 4439 subjects (age 40+ years) of 5324 individuals invited to participate (response rate 83.4%). The study was conducted in both a rural region (1973 subjects) and an urban region of Greater Beijing (2466 subjects).

METHODS

All participants underwent an interview, including questions about alcohol consumption and a detailed ophthalmic examination, including photography of the cornea, lens, and fundus.

MAIN OUTCOME MEASURES

Consumption of alcohol and systemic and ophthalmic parameters.

RESULTS

Information on alcohol consumption was obtained on 4141 subjects (93.3%), of whom 549 (13.3%) reported they consumed beer or wine. In multivariate analysis, alcohol consumption was significantly associated with the systemic parameters of lower age (P = 0.001), male gender (P<0.001), rural region (P<0.001), lower level of education (P = 0.01), and smoking (P<0.001). Alcohol consumption was not a significant risk factor for the prevalences of age-related macular degeneration (P = 0.24), open-angle glaucoma (P = 0.51), angle-closure glaucoma (P = 0.75), diabetic retinopathy (P = 0.35), retinal vein occlusion (P = 0.39), pterygium (P = 0.08), trachoma (P = 0.053), epiretinal membrane (P = 0.09), non-glaucomatous optic nerve atrophy (P = 0.55), dry eye (P = 0.86), cortical cataract (P = 0.67), subcapsular posterior cataract (P = 0.62), or nuclear cataract (P = 0.76), or with the ocular parameters of refractive error (P = 0.99), intraocular pressure (P = 0.19), retinal artery diameters (temporal inferior: P = 0.60), retinal vein diameters (temporal inferior: P = 0.41), or size of alpha zone and beta zone of parapapillary atrophy (P = 0.68).

CONCLUSIONS

When adjusted for the systemic parameters of age, gender, rural/urban region, level of education, and smoking, self-reported moderate consumption of alcohol does not have a significant effect on the prevalence of major ocular diseases or the physiologic parameters of intraocular pressure and refractive error.

Authors+Show Affiliations

Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. xlbio@yahoo.cnNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19712977

Citation

Xu, Liang, et al. "Prevalence of Alcohol Consumption and Risk of Ocular Diseases in a General Population: the Beijing Eye Study." Ophthalmology, vol. 116, no. 10, 2009, pp. 1872-9.
Xu L, You QS, Jonas JB. Prevalence of alcohol consumption and risk of ocular diseases in a general population: the Beijing Eye Study. Ophthalmology. 2009;116(10):1872-9.
Xu, L., You, Q. S., & Jonas, J. B. (2009). Prevalence of alcohol consumption and risk of ocular diseases in a general population: the Beijing Eye Study. Ophthalmology, 116(10), pp. 1872-9. doi:10.1016/j.ophtha.2009.04.014.
Xu L, You QS, Jonas JB. Prevalence of Alcohol Consumption and Risk of Ocular Diseases in a General Population: the Beijing Eye Study. Ophthalmology. 2009;116(10):1872-9. PubMed PMID: 19712977.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of alcohol consumption and risk of ocular diseases in a general population: the Beijing Eye Study. AU - Xu,Liang, AU - You,Qi Sheng, AU - Jonas,Jost B, Y1 - 2009/08/26/ PY - 2008/11/05/received PY - 2009/03/27/revised PY - 2009/04/03/accepted PY - 2009/8/29/entrez PY - 2009/8/29/pubmed PY - 2009/10/17/medline SP - 1872 EP - 9 JF - Ophthalmology JO - Ophthalmology VL - 116 IS - 10 N2 - OBJECTIVE: To examine the associations between alcohol consumption and ocular diseases in the adult population of mainland China. DESIGN: Population-based study. PARTICIPANTS: The Beijing Eye Study, performed in 2001, included 4439 subjects (age 40+ years) of 5324 individuals invited to participate (response rate 83.4%). The study was conducted in both a rural region (1973 subjects) and an urban region of Greater Beijing (2466 subjects). METHODS: All participants underwent an interview, including questions about alcohol consumption and a detailed ophthalmic examination, including photography of the cornea, lens, and fundus. MAIN OUTCOME MEASURES: Consumption of alcohol and systemic and ophthalmic parameters. RESULTS: Information on alcohol consumption was obtained on 4141 subjects (93.3%), of whom 549 (13.3%) reported they consumed beer or wine. In multivariate analysis, alcohol consumption was significantly associated with the systemic parameters of lower age (P = 0.001), male gender (P<0.001), rural region (P<0.001), lower level of education (P = 0.01), and smoking (P<0.001). Alcohol consumption was not a significant risk factor for the prevalences of age-related macular degeneration (P = 0.24), open-angle glaucoma (P = 0.51), angle-closure glaucoma (P = 0.75), diabetic retinopathy (P = 0.35), retinal vein occlusion (P = 0.39), pterygium (P = 0.08), trachoma (P = 0.053), epiretinal membrane (P = 0.09), non-glaucomatous optic nerve atrophy (P = 0.55), dry eye (P = 0.86), cortical cataract (P = 0.67), subcapsular posterior cataract (P = 0.62), or nuclear cataract (P = 0.76), or with the ocular parameters of refractive error (P = 0.99), intraocular pressure (P = 0.19), retinal artery diameters (temporal inferior: P = 0.60), retinal vein diameters (temporal inferior: P = 0.41), or size of alpha zone and beta zone of parapapillary atrophy (P = 0.68). CONCLUSIONS: When adjusted for the systemic parameters of age, gender, rural/urban region, level of education, and smoking, self-reported moderate consumption of alcohol does not have a significant effect on the prevalence of major ocular diseases or the physiologic parameters of intraocular pressure and refractive error. SN - 1549-4713 UR - https://www.unboundmedicine.com/medline/citation/19712977/Prevalence_of_alcohol_consumption_and_risk_of_ocular_diseases_in_a_general_population:_the_Beijing_Eye_Study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(09)00366-2 DB - PRIME DP - Unbound Medicine ER -