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Validation of prediction equations for estimating resting energy expenditure in obese Chinese children.

Abstract

OBJECTIVES

(1) To examine the validity of existing prediction equations (PREE) for estimating resting energy expenditure (REE) in obese Chinese children, (2) to correlate the measured REE (MREE) with anthropometric and biochemical parameters and (3) to derive a new PREE for local use.

DESIGN

Cross-sectional study.

SUBJECTS

100 obese children (71 boys) were studied.

MEASUREMENTS

All subjects underwent physical examination and anthropometric measurement. Upper and central body fat distribution was signified by centrality and conicity index respectively, and REE was measured by indirect calorimetry. Fat free mass (FFM) were measured by DEXA scan. Thirteen existing prediction equations for estimating REE were compared with MREE among these obese children. Fasting blood for glucose, lipid profile and insulin were obtained.

RESULTS

The overall, male and female median MREEs were 7.1 mJ/d (IR 6.2-8.4), 7.3 mJ/d (IR 6.3-9.7) and 6.9 mJ/d (IR 5.6-8.1) respectively. No sex difference was noted in MREE (p=0.203). Most of the equations except Schofield equation underestimated REE of our children. By multiple linear regression, MREE was positively correlated with FFM (p<0.0001), conicity index (p<0.001) and centrality index (p=0.001). A new equation for estimating REE for local use was derived as: REE=(17.4*logFFM)+(11.4*conicity index)-(2.4*centrality index)-31.3. The mean difference of new PREE-MREE was -0.011 mJ/d (SD 1.51) with an interclass correlation coefficient of 0.91.

CONCLUSION

None of the existing prediction equations were accurate in their estimation of REE, when applied to obese Chinese children. A new prediction equation has been derived for local use.

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  • Authors+Show Affiliations

    ,

    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR. dorothychan@cuhk.edu.hk

    , , , , , , ,

    Source

    MeSH

    Adolescent
    Blood Glucose
    Body Fat Distribution
    Body Mass Index
    Calorimetry, Indirect
    Child
    Cross-Sectional Studies
    Energy Metabolism
    Female
    Humans
    Insulin
    Linear Models
    Lipids
    Male
    Mathematics
    Obesity
    Rest
    Waist Circumference

    Pub Type(s)

    Journal Article
    Validation Studies

    Language

    eng

    PubMed ID

    19713185

    Citation

    Chan, Dorothy F Y., et al. "Validation of Prediction Equations for Estimating Resting Energy Expenditure in Obese Chinese Children." Asia Pacific Journal of Clinical Nutrition, vol. 18, no. 2, 2009, pp. 251-6.
    Chan DF, Li AM, Chan MH, et al. Validation of prediction equations for estimating resting energy expenditure in obese Chinese children. Asia Pac J Clin Nutr. 2009;18(2):251-6.
    Chan, D. F., Li, A. M., Chan, M. H., So, H. K., Chan, I. H., Yin, J. A., ... Nelson, E. A. (2009). Validation of prediction equations for estimating resting energy expenditure in obese Chinese children. Asia Pacific Journal of Clinical Nutrition, 18(2), pp. 251-6.
    Chan DF, et al. Validation of Prediction Equations for Estimating Resting Energy Expenditure in Obese Chinese Children. Asia Pac J Clin Nutr. 2009;18(2):251-6. PubMed PMID: 19713185.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Validation of prediction equations for estimating resting energy expenditure in obese Chinese children. AU - Chan,Dorothy F Y, AU - Li,Albert M, AU - Chan,Michael H M, AU - So,Hung Kwan, AU - Chan,Iris H S, AU - Yin,Jane A T, AU - Lam,Christopher W K, AU - Fok,Tai Fai, AU - Nelson,Edmund A S, PY - 2009/8/29/entrez PY - 2009/8/29/pubmed PY - 2009/10/2/medline SP - 251 EP - 6 JF - Asia Pacific journal of clinical nutrition JO - Asia Pac J Clin Nutr VL - 18 IS - 2 N2 - OBJECTIVES: (1) To examine the validity of existing prediction equations (PREE) for estimating resting energy expenditure (REE) in obese Chinese children, (2) to correlate the measured REE (MREE) with anthropometric and biochemical parameters and (3) to derive a new PREE for local use. DESIGN: Cross-sectional study. SUBJECTS: 100 obese children (71 boys) were studied. MEASUREMENTS: All subjects underwent physical examination and anthropometric measurement. Upper and central body fat distribution was signified by centrality and conicity index respectively, and REE was measured by indirect calorimetry. Fat free mass (FFM) were measured by DEXA scan. Thirteen existing prediction equations for estimating REE were compared with MREE among these obese children. Fasting blood for glucose, lipid profile and insulin were obtained. RESULTS: The overall, male and female median MREEs were 7.1 mJ/d (IR 6.2-8.4), 7.3 mJ/d (IR 6.3-9.7) and 6.9 mJ/d (IR 5.6-8.1) respectively. No sex difference was noted in MREE (p=0.203). Most of the equations except Schofield equation underestimated REE of our children. By multiple linear regression, MREE was positively correlated with FFM (p<0.0001), conicity index (p<0.001) and centrality index (p=0.001). A new equation for estimating REE for local use was derived as: REE=(17.4*logFFM)+(11.4*conicity index)-(2.4*centrality index)-31.3. The mean difference of new PREE-MREE was -0.011 mJ/d (SD 1.51) with an interclass correlation coefficient of 0.91. CONCLUSION: None of the existing prediction equations were accurate in their estimation of REE, when applied to obese Chinese children. A new prediction equation has been derived for local use. SN - 0964-7058 UR - https://www.unboundmedicine.com/medline/citation/19713185/Validation_of_prediction_equations_for_estimating_resting_energy_expenditure_in_obese_Chinese_children_ L2 - http://apjcn.nhri.org.tw/server/APJCN/18/2/251.pdf DB - PRIME DP - Unbound Medicine ER -