Tags

Type your tag names separated by a space and hit enter

Prevalence and determinants of age-related macular degeneration in central Sri Lanka: the Kandy Eye Study.
Br J Ophthalmol. 2010 Feb; 94(2):150-3.BJ

Abstract

AIMS

To determine the prevalence, associations and risk factors for age-related macular degeneration (ARMD) in central Sri Lanka.

METHODS

The study was a population-based, cross-sectional survey of residents aged > or = 40 years in rural Sri Lanka. ARMD was assessed on dilated fundoscopy using the International Age-Related Maculopathy Epidemiology Study Group classification system.

RESULTS

Of the 1721 subjects identified, 1375 participated (79.9%). Of the participants, 1013 were aged > or = 50 years (73.6%). The prevalence of any ARMD (adjusted for study design) was 4.72 (95% CI 2.22 to 7.20)% with 3.82 (95% CI 1.60 to 6.04)% early ARMD and 1.70 (95% CI 0.14 to 3.27)% late ARMD. Age (p<0.001) and Sinhalese ethnicity (p = 0.016) were significantly associated with ARMD. Men had a tendency toward a higher prevalence of ARMD than women, although this was not statistically significant (p = 0.081). Ocular risk factors such as cortical cataract (p = 0.024) and pseudophakia (p = 0.003) were associated with ARMD on the univariate but not multivariate analyses. Illiteracy and the identification of social supports were significantly associated with ARMD on univariate analyses. However, only social support was statistically significant after multivariate analysis (p = 0.024).

CONCLUSIONS

Although the prevalence of ARMD is slightly lower in Sri Lanka than surrounding regions, it contributes to a higher proportion of visual impairment, including blindness. Risk factors include age and Sinhalese ethnicity.

Authors+Show Affiliations

South Australian Institute of Ophthalmology, North Terrace, Adelaide, South Australia, Australia 5000. lgoold@med.usyd.edu.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19713196

Citation

Goold, L A., et al. "Prevalence and Determinants of Age-related Macular Degeneration in Central Sri Lanka: the Kandy Eye Study." The British Journal of Ophthalmology, vol. 94, no. 2, 2010, pp. 150-3.
Goold LA, Edussuriya K, Sennanayake S, et al. Prevalence and determinants of age-related macular degeneration in central Sri Lanka: the Kandy Eye Study. Br J Ophthalmol. 2010;94(2):150-3.
Goold, L. A., Edussuriya, K., Sennanayake, S., Senaratne, T., Selva, D., Sullivan, T. R., & Casson, R. J. (2010). Prevalence and determinants of age-related macular degeneration in central Sri Lanka: the Kandy Eye Study. The British Journal of Ophthalmology, 94(2), 150-3. https://doi.org/10.1136/bjo.2009.163808
Goold LA, et al. Prevalence and Determinants of Age-related Macular Degeneration in Central Sri Lanka: the Kandy Eye Study. Br J Ophthalmol. 2010;94(2):150-3. PubMed PMID: 19713196.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and determinants of age-related macular degeneration in central Sri Lanka: the Kandy Eye Study. AU - Goold,L A, AU - Edussuriya,K, AU - Sennanayake,S, AU - Senaratne,T, AU - Selva,D, AU - Sullivan,T R, AU - Casson,R J, Y1 - 2009/08/26/ PY - 2009/8/29/entrez PY - 2009/8/29/pubmed PY - 2010/3/6/medline SP - 150 EP - 3 JF - The British journal of ophthalmology JO - Br J Ophthalmol VL - 94 IS - 2 N2 - AIMS: To determine the prevalence, associations and risk factors for age-related macular degeneration (ARMD) in central Sri Lanka. METHODS: The study was a population-based, cross-sectional survey of residents aged > or = 40 years in rural Sri Lanka. ARMD was assessed on dilated fundoscopy using the International Age-Related Maculopathy Epidemiology Study Group classification system. RESULTS: Of the 1721 subjects identified, 1375 participated (79.9%). Of the participants, 1013 were aged > or = 50 years (73.6%). The prevalence of any ARMD (adjusted for study design) was 4.72 (95% CI 2.22 to 7.20)% with 3.82 (95% CI 1.60 to 6.04)% early ARMD and 1.70 (95% CI 0.14 to 3.27)% late ARMD. Age (p<0.001) and Sinhalese ethnicity (p = 0.016) were significantly associated with ARMD. Men had a tendency toward a higher prevalence of ARMD than women, although this was not statistically significant (p = 0.081). Ocular risk factors such as cortical cataract (p = 0.024) and pseudophakia (p = 0.003) were associated with ARMD on the univariate but not multivariate analyses. Illiteracy and the identification of social supports were significantly associated with ARMD on univariate analyses. However, only social support was statistically significant after multivariate analysis (p = 0.024). CONCLUSIONS: Although the prevalence of ARMD is slightly lower in Sri Lanka than surrounding regions, it contributes to a higher proportion of visual impairment, including blindness. Risk factors include age and Sinhalese ethnicity. SN - 1468-2079 UR - https://www.unboundmedicine.com/medline/citation/19713196/Prevalence_and_determinants_of_age_related_macular_degeneration_in_central_Sri_Lanka:_the_Kandy_Eye_Study_ L2 - http://bjo.bmj.com/cgi/pmidlookup?view=long&amp;pmid=19713196 DB - PRIME DP - Unbound Medicine ER -